Zobrazeno 1 - 10
of 427
pro vyhledávání: ''
Autor:
Ratna K. Vadlamudi, Jinyou Liu, Suryavathi Viswanadhapalli, Gangadhara R. Sareddy, Mei Zhou, Lauren Garcia, Rajeshwar Rao Tekmal, Binoj C. Nair, Edward R. Kost, Tyler J. Curiel, Rong Li, Manjeet K. Rao
Publikováno v:
Oncotarget
Ovarian cancer is the deadliest of all gynecologic cancers. Despite success with initial chemotherapy, the majority of patients relapse with an incurable disease. Development of chemotherapy resistance is a major factor for poor long-term survival in
Publikováno v:
Oncotarget
UBC9 is an E2-conjugating enzyme that is required for SUMOylation and has been implicated in regulating several critical cellular pathways. UBC9 is overexpressed in certain tumors, such as lung adenocarcinoma, ovarian carcinoma and melanoma, which im
Autor:
Hongchuan Jin, Jinye Xu, Zhinong Jiang, Qiqi Shi, Yu Weng, Jianwei Zhou, Xian Wang, Wenxia Xu, Xiaoling Qian, Jiaqiu Li, Lifeng Feng
Publikováno v:
Oncotarget
Chemotherapy is the major choice for the cancer treatment of early and advanced stages. However, intrinsic or acquired drug resistance significantly restricts the clinical efficacy of chemotherapy. It is critical to develop novel approaches to detect
Autor:
Osamu Nagano, Isao Sakaguchi, Hironori Tashiro, Koichi Fujimoto, Chenyan Li, Hidetaka Katabuchi, Takeshi Motohara, Hideyuki Saya, Dashdemberel Narantuya, Shingo Tayama
Publikováno v:
Oncotarget
// Shingo Tayama 1, * , Takeshi Motohara 1, * , Dashdemberel Narantuya 1 , Chenyan Li 1 , Koichi Fujimoto 1 , Isao Sakaguchi 1 , Hironori Tashiro 2 , Hideyuki Saya 3 , Osamu Nagano 3 and Hidetaka Katabuchi 1 1 Department of Obstetrics and Gynecology,
Autor:
Shih-Pin Chiou, Chuang-Yu Lin, Yi-Wen Chen, I-An Wang, Yuh-Jin Liang, Yu-Ju Lin, Ming-Yi Ho, Ya-Hui Wang, Tsung-Lung Chou, Li-Tzu Li, John Yu, Chen-Yu Wang
Publikováno v:
Oncotarget
// Yuh-Jin Liang 1 , Chen-Yu Wang 2 , I-An Wang 1 , Yi-Wen Chen 1 , Li-Tzu Li 1 , Chuang-Yu Lin 1 , Ming-Yi Ho 1 , Tsung-Lung Chou 1 , Ya-Hui Wang 1 , Shih-Pin Chiou 1 , Yu-Ju Lin 1 and John Yu 1, 3 1 Institute of Stem Cell and Translational Cancer R
Autor:
Jin Shu, Li-Li Zhuang, Jun Qian, Ling Li, Lan-Bo Zhou, Guo-Ping Zhou, Hai-Guo Yu, Rui Jin, Zhi-Dan Fan, Lu-Lu Wang
Publikováno v:
Oncotarget
Interferon regulatory factor 5 (IRF5) plays a critical role in the induction of type I interferon, proinflammatory cytokines and chemokines, and participates in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus (SLE). Howev
Publikováno v:
Oncotarget
// Nandini Kundu 1, 2 , Angelika Brekman 1, 3 , Jun Yeob Kim 1 , Gu Xiao 1 , Chong Gao 1, 2 and Jill Bargonetti 1, 2, 3, 4 1 The Department of Biological Sciences Hunter College, City University of New York, New York, NY 10065, USA 2 PhD Program in B
Autor:
Hans Petter Eikesdal, Per Eystein Lønning, Stian Knappskog, Synnøve Yndestad, Eilin Austreid, Ida Svanberg
Publikováno v:
Oncotarget
OncoTarget
41227-41241
OncoTarget
41227-41241
Anthracyclines are key components of human breast cancer chemotherapy. Here, we explored the role of Akt signaling in anthracycline resistance. The antitumor activity of doxorubicin and Akt inhibitor A-443654 alone or combined was examined in estroge
Autor:
Pierre Vandenberghe, Perrine Hague, Christophe Erneux, Pieter Demetter, Vincent Vc Manganiello, Steven Sc Hockman, Jean-Marie Vanderwinden
Publikováno v:
Oncotarget
// Pierre Vandenberghe 1 , Perrine Hague 1 , Steven C. Hockman 2 , Vincent C. Manganiello 2, ** , Pieter Demetter 3 , Christophe Erneux 4, * and Jean-Marie Vanderwinden 1, * 1 Laboratory of Neurophysiology, Faculty of Medicine, Universite Libre de Br
Autor:
Shing-Jyh Chang, Hsin-Yueh Yeo, Kuo-Ming Chang, Tze-Chien Chen, Yung-Jen Chuang, Zih-Yin Lai, Ya-Tse Chen
Publikováno v:
Oncotarget
// Zih-Yin Lai 1 , Hsin-Yueh Yeo 1 , Ya-Tse Chen 1 , Kuo-Ming Chang 2 , Tze-Chien Chen 3 , Yung-Jen Chuang 1 and Shing-Jyh Chang 4 1 Department of Medical Science and Institute of Bioinformatics and Structural Biology, National Tsing Hua University,