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of 474
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Autor:
Min Zhang, Zhen Xiang, Feng Wang, Rong Shan, Ling Li, Juan Chen, Bao‑An Liu, Juan Huang, Lun‑Quan Sun, Wei‑Bing Zhou
Publikováno v:
Oncology Reports
Breast cancer (BRCA) is one of the most common malignancies encountered in women worldwide. Lipid metabolism has been found to be involved in cancer progression. Steroidogenic acute regulatory protein‑related lipid transfer 4 (STARD4) is an importa
Publikováno v:
Oncology Reports
TRAIL‑R2 (DR5), one of the death receptors, can activate the extrinsic apoptosis pathway, while cellular FLICE‑inhibitory protein (c‑FLIP) can inhibit this pathway. Both of them play important roles in the occurrence and development of most tum
Autor:
Meijuan Hua, Huiyun Yang, Weiling Li, Tieliang Ma, Hongdi Zhu, Xiaofang Yan, Yan Ren, Haifeng Wu, Xin Zuo
Publikováno v:
Oncology Reports
Endometrial carcinoma (EC) is the most common cancer in women worldwide, yet little is known about the underlying molecular basis of EC development. LINC01224, a novel long non-coding (lnc)RNA, was recently identified as an oncogene in various types
Autor:
Cuimeng Tian, Jianhui Li, Ji Ming Wang, Teng Ma, Jiaqiang Huang, Shuye Lin, Keqiang Chen, Bin Liu, Wanghua Gong
Publikováno v:
Oncology Reports
Disruption in mucins (MUCs) is involved in cancer development and metastasis and is thus used as a biomarker. Non-small cell lung carcinoma (NSCLC) is characterized by heterogeneous genetic and epigenetic alterations. Lung adenocarcinoma (LUAD) and s
Autor:
Jin Liang, Xiao Chen, Minjie He, Hongxing Zhang, Chuanzheng Sun, Min Hong, Yuanyuan Xu, Weiqing Liu, Change Gao, Zhaoming Zhong
Publikováno v:
Oncology Reports
The primary reasons for the treatment failure of patients with oral tongue squamous cell carcinoma (OTSCC) are metastasis and tumor recurrence. Identifying the exact mechanisms underlying metastasis is a key point in improving patient prognosis. It h
Publikováno v:
Oncology Reports.
Establishing a prognostic genetic signature closely related to the tumor immune microenvironment (TIME) to predict clinical outcomes is necessary. Using the Gene Expression Omnibus (GEO) database of a non‑small cell lung cancer (NSCLC) cohort and t
Autor:
Yue Zhou, Fang Wang, Pan Liang, Song-Wei Yue, Jianbo Gao, Junqiang Dong, Yonggao Zhang, Yijuan Wei, Wenlong Zhai, Hua Guo
Publikováno v:
Oncology Reports.
The differential expression of a featured set of genes may serve as a diagnostic biomarker in hepatocellular carcinoma (HCC) patients. The aim of this study was to identify prognostic biomarkers for the diagnosis and survival of HCC based on the anal
Publikováno v:
Oncology Reports
Glucose-regulated protein 78 (GRP78) was revealed to be associated with the radioresistance of nasopharyngeal carcinoma (NPC) in our previous study. GRP78 is a highly expressed cell surface protein, and holds great promise as a cancer specific target
Publikováno v:
Oncology Reports.
Cancer‑associated fibroblasts (CAFs) are known to be essential in cancer initiation and development. However, the role of CAFs in promoting ovarian cancer (OC) invasion remains to be fully elucidated. To address this in the present study, 49 clinic
Autor:
Xu Ding, Yang Zheng, Zhao Wang, Wei Zhang, Yibo Dong, Wantao Chen, Jiang Li, Weiming Chu, Yi Zhong, Li Mao, Xiaomeng Song, Yunong Wu
Publikováno v:
Oncology Reports
Notch1 signaling is essential for tissue development and tumor progression. This signaling pathway has also been implicated in oral leukoplakia (OL) and oral squamous cell carcinoma (OSCC). However, the role of Notch1 expression in OL and its maligna