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Publikováno v:
Oncology Reports
TRAIL‑R2 (DR5), one of the death receptors, can activate the extrinsic apoptosis pathway, while cellular FLICE‑inhibitory protein (c‑FLIP) can inhibit this pathway. Both of them play important roles in the occurrence and development of most tum
Publikováno v:
Oncology Reports.
Establishing a prognostic genetic signature closely related to the tumor immune microenvironment (TIME) to predict clinical outcomes is necessary. Using the Gene Expression Omnibus (GEO) database of a non‑small cell lung cancer (NSCLC) cohort and t
Autor:
Yue Zhou, Fang Wang, Pan Liang, Song-Wei Yue, Jianbo Gao, Junqiang Dong, Yonggao Zhang, Yijuan Wei, Wenlong Zhai, Hua Guo
Publikováno v:
Oncology Reports.
The differential expression of a featured set of genes may serve as a diagnostic biomarker in hepatocellular carcinoma (HCC) patients. The aim of this study was to identify prognostic biomarkers for the diagnosis and survival of HCC based on the anal
Publikováno v:
Oncology Reports. 38:1043-1050
B7-H3 is an immune regulatory molecule whose aberrant expression in tumors is associated with adverse outcomes. Upregulation of B7-H3 may promote tumor cell proliferation and metastasis in vitro, but the role of B7-H3 in cervical cancer has not yet b
Autor:
Ji Sang Kim, Yun-Sok Ha, Xuan Mei Piao, Ho Sun Shon, Sang Cheol Lee, Hyung Yoon Yoon, Seok Joong Yun, Sang-Won Kim, Ghil Suk Yoon, Sang Keun Lee, Ho Won Kang, Sung Min Kim, Yong-June Kim, Keun Ho Ryu, Wooyeong Jang, Sung Pil Seo, Won-Tae Kim, Wun-Jae Kim, Young Joon Byun, Tae Gyun Kwon
Publikováno v:
Oncology Reports.
The present study aimed to identify novel methylation markers of clear cell renal cell carcinoma (ccRCC) using microarray methylation analysis and evaluate their prognostic relevance in patient samples. To identify cancer‑specific methylated biomar
Autor:
Gerd Otto, Christoph Düber, Maria Hoppe‑Lotichius, Frank Simon, Anja Lautem, Arno Schad, Tim Zimmermann, Hauke Lang, Jens Mittler, Johanna Vollmar, Peter R. Galle
Publikováno v:
Oncology Reports.
Hepatocellular carcinoma (HCC) is one of the most common human malignancies, the incidence of which is growing worldwide. The prognosis of HCC is very poor and it is often accompanied by a high rate of recurrence. Conventional chemotherapeutic approa
Autor:
Deyin Xing, Jiayun Lu
Publikováno v:
Oncol Rep
Adenoid cystic carcinomas (ACCs) and adenoid basal carcinomas (ABCs) in the lower female genital tract are very rare. Data on the clinicopathologic features and survival outcomes of ACCs and ABCs in the lower female genital tract are limited to case
Publikováno v:
Oncology Reports
Increased expression of interleukin 6 (IL-6) is associated with poor prognosis and chemoresistance in many different carcinomas, but its role in head and neck squamous cell carcinoma (HNSCC) is still unsettled. Analyzing tumorous mRNA expression data
Autor:
Mingquan Chen, Ning Li, Qi Cheng, Suxia Bao, Jianming Zheng, Mengqi Zhu, Chong Huang, Qingxia Ling, Shengsen Chen, Kangkang Yu
Publikováno v:
Oncology Reports
Dual oxidase 1 (DUOX1), which is the main source of reactive oxygen species (ROS) production in the airway, can be silenced in human lung cancer and hepatocellular carcinomas. However, the prognostic value of DUOX1 expression in hepatocellular carcin
Autor:
Kwang Jae Cho, Seung-Hyun Jung, In Chul Nam, Seon Hee Yim, Yeun-Jun Chung, Sung-Won Park, Min-Sik Kim, Young Hoon Joo
Publikováno v:
Oncology Reports. 35:2207-2215
Although concomitant chemoradiotherapy (CCRT) has recently become a mainstay of a primary treatment modality in advanced head and neck squamous cell carcinoma (HNSCC), some of the patients experience CCRT failure. If we can predict the CCRT outcomes,