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Autor:
Julia Salleron, Jean‑Christophe Faivre, C. Pflumio, Gilles Dolivet, Xavier Sastre‑Garau, Jacques Thomas, Lionnel Geoffrois, Christian Borel
Publikováno v:
Oncology Reports. 45:1273-1283
The immune landscape of head and neck squamous cell carcinoma in pretreated areas remains poorly documented. We aimed to assess the tumor microenvironment for biomarkers of antitumor immune responses in tumors in previously irradiated areas compared
Publikováno v:
Oncology Reports
TRAIL‑R2 (DR5), one of the death receptors, can activate the extrinsic apoptosis pathway, while cellular FLICE‑inhibitory protein (c‑FLIP) can inhibit this pathway. Both of them play important roles in the occurrence and development of most tum
Publikováno v:
Oncology Reports.
Establishing a prognostic genetic signature closely related to the tumor immune microenvironment (TIME) to predict clinical outcomes is necessary. Using the Gene Expression Omnibus (GEO) database of a non‑small cell lung cancer (NSCLC) cohort and t
Autor:
Li-Li Wang, Sheng‑You Liao, Yi Ding, Michael Q. Zhang, Li Yu, Na Lv, Sai Huang, Yong‑Hui Li, Baoli Zhu, Yang Chen, Wen‑Wen Liu, Liang Sun, Yi Zhao, Chao Lv, Qian Xiong
Publikováno v:
Oncology Reports
Single‑cell RNA sequencing (scRNA‑seq) of bone marrow or peripheral blood samples from patients with acute myeloid leukemia (AML) enables the characterization of heterogeneous malignant cells. A total of 87 cells from two patients with t(8;21) AM
Publikováno v:
Oncology reports. 42(4)
MicroRNAs (miRNAs/miRs) act as markers for various cancers, including bladder cancer (BC). Plasma miRNAs are potential biomarkers for the noninvasive diagnosis and long‑term surveillance of BC. The aim of the present study was to identify diagnosti
Publikováno v:
Oncology Reports. 36:1901-1908
The present study aimed to analyze the role and mechanism of miR-15b in hepatocellular carcinoma (HCC) after curative hepatectomy. Tissue samples from 13 patients with HCC who were operated on at the Chinese PLA General Hospital from March 2014 to Ma
Autor:
Bing-Hua Jiao, Jun Li, Yizhou Wang, Xuying Wan, Aimin Huang, Feng Shen, Zhenlin Yan, Kui Wang, Jingfeng Liu, Yong Xia, Lehua Shi, Yongjie Zhang, Jian Liu
Publikováno v:
Oncology Reports. 34:3174-3186
Notch1 has previously been implicated in the carcinogenesis of hepatocellular carcinoma (HCC). The present study aimed to investigate the prognostic value of Notch1 in early stage HCC patients after hepatectomy. The differential expression of Notch1
Publikováno v:
Oncology Reports
Lung cancer is the most common cause of cancer-related deaths, and early diagnosis and targeted therapy are extremely important in the treatment of this disease. Sperm-associated antigen 4 (SPAG4) was recently found to be a novel cancer biomarker. In
Publikováno v:
Oncology reports. 41(2)
Mitochondrial (mt) DNA has been long suggested to contribute to carcinogenesis, and a variety of mutations in mtDNA have been confirmed to be related to various early stages of cancers; these data revealed that the detection of mtDNA in clinical samp
Autor:
Hao� Tian, Jian‑Zhong� Wu, Xia He, Kai� Ding, Xiao‑Hong� Wang, Li� Yin, You‑You� Xia
Publikováno v:
Oncology Reports.
Raf-1 proto-oncogene, serine/threonine kinase (Raf1) acts as a part of the RAS/RAF/MEK/ERK signaling pathway and regulates cell migration, apoptosis and differentiation. However, few studies are available on the expression and clinical significance o