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Publikováno v:
Oncology Reports
Clear cell renal cell carcinoma (ccRCC) is one of the most common types of malignant tumors and early detection contributes to a better prognosis. Finding new biomarkers for the diagnosis or treatment remains meaningful. DEF6 guanine nucleotide excha
Autor:
Zhiguo Zhou, Zhixue Ren, Ruoying Deng, Zhicong Wang, Li Jing, Yibing Liu, Yi zhang, Shuai Shi, Li Feng
Publikováno v:
Oncology Reports
Colorectal cancer (CRC) is the third most common cancer worldwide. At present, there are limited effective biomarkers of CRC. The present study aimed to identify potential signatures associated with the tumorigenesis and prognosis of CRC using public
Autor:
Shumpei Ishikawa, Satoshi Wada, Makoto Watanabe, Yutaro Kubota, Masahiko Murakami, Kiyoshi Yoshimura, Ryotaro Ohkuma, Hirotsugu Ariizumi, Masafumi Takimoto, Kazuyuki Hamada, Midori Shida, Atsushi Horiike, Junji Tsurutani, Kiyohiro Ando, Rie Onoue, Daisuke Komura, Yuya Hirasawa, Erica Yada, Tomoko Norose, Tetsuro Sasada, Shinichi Kobayashi, Nobuyuki Ohike, Takuya Tsunoda, Takeshi Aoki, Tomoyuki Ishiguro
Publikováno v:
Oncology Reports
Pancreatic cancer has extremely poor prognosis, warranting the discovery of novel therapeutic and prognostic markers. The expression of polymeric immunoglobulin receptor (pIgR), a key component of the mucosal immune system, is increased in several ca
BMI-1 promotes invasion and metastasis in endometrial adenocarcinoma and is a poor prognostic factor
Publikováno v:
Oncology Reports
Endometrial adenocarcinoma is one of the most common types of gynecological malignancies and its incidence and mortality rates are increasing. Due to tumor recurrence and metastasis, the overall five‑year survival rate of patients with endometrial
Autor:
Kai Xu, Dao‑Ying Yuan, Bin Zhang, Keyi Li, Jun Li, Li‑Ping Sun, Zhen Meng, Bo Zou, Jian‑Lin Liu, Jing Cui
Publikováno v:
Oncology Reports
Oral squamous cell carcinoma (OSCC), with high potential for metastasis, is the most common malignant tumor of the head and neck. Cancer‑associated fibroblasts (CAFs) are the main stromal cells in the microenvironment and aggravate tumor progressio
Autor:
Hisamori Kato, Mitsuyo Yoshihara, Tomoyuki Yokose, Yohei Miyagi, Shinya Sato, Etsuko Miyagi, Shohei Myoba, Yoshiyasu Nakamura, Yukihide Ota, Norihisa Ohtake, Shiro Koizume, Tomoko Takahashi
Publikováno v:
Oncology Reports
Tissue factor pathway inhibitor‑2 (TFPI‑2) is a promising candidate as a serum biomarker of ovarian clear cell carcinoma (OCCC), a lethal histological subtype of epithelial ovarian cancer (EOC). TFPI‑2 is a secreted serine protease inhibitor th
Autor:
Shi‑Quan Liu, Jin‑Xiu Zhang, Si‑Man Li, Zhe Ye, Ye Zhu, Jie‑An Huang, Peng Peng, Lan Lin, Meng‑Bin Qin, Qian Song, Li‑Hua Xie
Publikováno v:
Oncology Reports
Tricellulin is a tight‑junction transmembrane protein that regulates cell‑cell interactions. Altered tricellulin expression could promote tumor cell invasions and metastasis in human cancers. The present study assessed tricellulin expression in c
Publikováno v:
Oncology Reports
Endometrial cancer is one of the three major malignant tumors of the female reproductive system. Although cyclin-dependent kinase 9 (CDK9) has a definitive pathogenic role in various types of cancer, little is known concerning its function in endomet
Publikováno v:
Oncology Reports
As the major component of the tumor matrix, collagen greatly influences tumor invasion and prognosis. The present study compared the remodeling of collagen and collagenase in 56 patients with colorectal cancer (CRC) using Sirius red stain and immunoh
Autor:
Yu Zhang, Xiufang Zhang, Xiaoning Luo, Jue He, Huabin Zhu, Jinghua Zhong, Nanying Zhong, Fuping Tu, Li Huang, Xiangcai Wang, Zheng Guo
Publikováno v:
Oncology Reports
Colorectal cancer (CRC) is a common cancer worldwide, and its treatment strategies are limited. The underlying mechanism of CRC progression remains to be determined. Telomere maintenance 2 (TELO2) is a mTOR-interacting protein. Both the role and mole