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Autor:
Kukiko Sakihama, Shinjiro Nagao, Akiko Fujimura, Kazunori Nakayama, Shu Ichimiya, Hideya Onishi, Yasuhiro Oyama, Satoko Koga, Akira Imaizumi, Yoshinao Oda, Masafumi Nakamura
Publikováno v:
Oncology Reports
We previously reported that Hedgehog (Hh) signal was enhanced in gallbladder cancer (GBC) and was involved in the induction of malignant phenotype of GBC. In recent years, therapeutics that target Hh signaling have focused on molecules downstream of
Publikováno v:
Oncology Reports
Emerging evidence has indicated that histone modification and its related regulators are involved in the progression of multiple myeloma (MM) cells. In the present study, the expression of Jumonji C domain‑containing 2 (JMJD2) was examined in both
Publikováno v:
Oncology Reports
Hsa_circ_0016760 expression has been reported to be increased in non‑small cell lung cancer (NSCLC). The present study was designed to explore the role and mechanism of hsa_circ_0016760 in regulating NSCLC progression. In total, 60NSCLC patients we
Publikováno v:
Oncology Reports
The aim of the present study was to investigate the effects of microRNA (miR)‑29b‑3p gene promoter methylation on angiogenesis, invasion, and migration in human pancreatic cancer. Prediction of promoter methylation of miR‑29b‑3p was performed
Publikováno v:
Oncology Reports
Currently, the prognosis of acute myeloid leukemia (AML) is poor. In the AML microenvironment, bone marrow (BM) mesenchymal stem cells (BMMSCs) serve an important role in protecting AML cells from chemotherapy‑induced apoptosis. The present study a
Autor:
Tiefu Xiong, Hongrui Zhan, Yawen Li, Zeng Zhang, Qiong Deng, Fangfang Chen, Liping Chen, Jing Ye
Publikováno v:
Oncology Reports
The long noncoding RNA cancer susceptibility candidate 9 (CASC9) has been revealed to be an oncogenic gene in several types of cancer, and high CASC9 expression is related to tumorigenesis and cancer progression. However, the role of CASC9 in bladder
Autor:
Min Zhang, Zhen Xiang, Feng Wang, Rong Shan, Ling Li, Juan Chen, Bao‑An Liu, Juan Huang, Lun‑Quan Sun, Wei‑Bing Zhou
Publikováno v:
Oncology Reports
Breast cancer (BRCA) is one of the most common malignancies encountered in women worldwide. Lipid metabolism has been found to be involved in cancer progression. Steroidogenic acute regulatory protein‑related lipid transfer 4 (STARD4) is an importa
Autor:
Charulochana Subramony, Amit Reddy, Sejong Bae, Logan Fair, Christian R. Gomez, W. Shannon Orr, Veena Shenoy, Christopher J. Lahr, Marcelo J. Sakiyama, Sameer Al Diffalha, Sumit Agarwal, Ingrid Espinoza, Upender Manne, Xinchun Zhou, Teja Poosarla
Publikováno v:
Oncology Reports
In colorectal cancer (CRC), high expression of trefoil factor 3 (TFF3) is associated with tumor progression and reduced patient survival; however, bioinformatics analyses of public 'omics' databases show low TFF3 expression in CRCs as compared to nor
Publikováno v:
Oncology Reports
Long non‑coding RNA growth arrest specific 5 (GAS5) exerts inhibitory effects through the modulation of several target microRNAs (miRs) in cancer. However, its potential roles and underlying relationship during colorectal cancer (CRC) progression a
Autor:
Wei‑Yi Zhang, Jia‑Lin Feng, Li‑Xuan Liu, Hao‑Lian Zhan, Ming‑Kai Li, Ling‑Fei Wu, Rui‑Pei Chen
Publikováno v:
Oncology Reports
Esophageal squamous cell carcinoma (ESCC) is the main subtype of esophageal cancer in China, and the prognosis of patients remains poor mainly due to the occurrence of lymph node and distant metastasis. The long non‑coding RNA (lncRNA) maternally e