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Autor:
Kukiko Sakihama, Shinjiro Nagao, Akiko Fujimura, Kazunori Nakayama, Shu Ichimiya, Hideya Onishi, Yasuhiro Oyama, Satoko Koga, Akira Imaizumi, Yoshinao Oda, Masafumi Nakamura
Publikováno v:
Oncology Reports
We previously reported that Hedgehog (Hh) signal was enhanced in gallbladder cancer (GBC) and was involved in the induction of malignant phenotype of GBC. In recent years, therapeutics that target Hh signaling have focused on molecules downstream of
Publikováno v:
Oncology Reports
Hsa_circ_0016760 expression has been reported to be increased in non‑small cell lung cancer (NSCLC). The present study was designed to explore the role and mechanism of hsa_circ_0016760 in regulating NSCLC progression. In total, 60NSCLC patients we
Publikováno v:
Oncology Reports
The aim of the present study was to investigate the effects of microRNA (miR)‑29b‑3p gene promoter methylation on angiogenesis, invasion, and migration in human pancreatic cancer. Prediction of promoter methylation of miR‑29b‑3p was performed
Autor:
Tiefu Xiong, Hongrui Zhan, Yawen Li, Zeng Zhang, Qiong Deng, Fangfang Chen, Liping Chen, Jing Ye
Publikováno v:
Oncology Reports
The long noncoding RNA cancer susceptibility candidate 9 (CASC9) has been revealed to be an oncogenic gene in several types of cancer, and high CASC9 expression is related to tumorigenesis and cancer progression. However, the role of CASC9 in bladder
Autor:
Min Zhang, Zhen Xiang, Feng Wang, Rong Shan, Ling Li, Juan Chen, Bao‑An Liu, Juan Huang, Lun‑Quan Sun, Wei‑Bing Zhou
Publikováno v:
Oncology Reports
Breast cancer (BRCA) is one of the most common malignancies encountered in women worldwide. Lipid metabolism has been found to be involved in cancer progression. Steroidogenic acute regulatory protein‑related lipid transfer 4 (STARD4) is an importa
Autor:
Charulochana Subramony, Amit Reddy, Sejong Bae, Logan Fair, Christian R. Gomez, W. Shannon Orr, Veena Shenoy, Christopher J. Lahr, Marcelo J. Sakiyama, Sameer Al Diffalha, Sumit Agarwal, Ingrid Espinoza, Upender Manne, Xinchun Zhou, Teja Poosarla
Publikováno v:
Oncology Reports
In colorectal cancer (CRC), high expression of trefoil factor 3 (TFF3) is associated with tumor progression and reduced patient survival; however, bioinformatics analyses of public 'omics' databases show low TFF3 expression in CRCs as compared to nor
Autor:
Fangyuan Li, Zhang Sumei, Anqi Wang, Dan Guo, Bo Long, Xiaoxiao Zhao, Binglu Li, Jian Sun, Dingyan Cao
Publikováno v:
Oncology Reports
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Circular RNAs (circRNAs) are a novel class of RNAs, with higher stability and tissue specificity, which may be of value as novel clinical markers. High‑throughput RNA sequ
Publikováno v:
Oncology Reports
Kindlin‑2 plays a carcinogenic or tumor‑suppressor role in various tumors. However, its role in cervical cancer remains unclear. In the present study, kindlin‑2 expression was first analyzed using public expression data and clinical specimens.
Autor:
Shumpei Ishikawa, Satoshi Wada, Makoto Watanabe, Yutaro Kubota, Masahiko Murakami, Kiyoshi Yoshimura, Ryotaro Ohkuma, Hirotsugu Ariizumi, Masafumi Takimoto, Kazuyuki Hamada, Midori Shida, Atsushi Horiike, Junji Tsurutani, Kiyohiro Ando, Rie Onoue, Daisuke Komura, Yuya Hirasawa, Erica Yada, Tomoko Norose, Tetsuro Sasada, Shinichi Kobayashi, Nobuyuki Ohike, Takuya Tsunoda, Takeshi Aoki, Tomoyuki Ishiguro
Publikováno v:
Oncology Reports
Pancreatic cancer has extremely poor prognosis, warranting the discovery of novel therapeutic and prognostic markers. The expression of polymeric immunoglobulin receptor (pIgR), a key component of the mucosal immune system, is increased in several ca
BMI-1 promotes invasion and metastasis in endometrial adenocarcinoma and is a poor prognostic factor
Publikováno v:
Oncology Reports
Endometrial adenocarcinoma is one of the most common types of gynecological malignancies and its incidence and mortality rates are increasing. Due to tumor recurrence and metastasis, the overall five‑year survival rate of patients with endometrial