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BMI-1 promotes invasion and metastasis in endometrial adenocarcinoma and is a poor prognostic factor
Publikováno v:
Oncology Reports
Endometrial adenocarcinoma is one of the most common types of gynecological malignancies and its incidence and mortality rates are increasing. Due to tumor recurrence and metastasis, the overall five‑year survival rate of patients with endometrial
Publikováno v:
Oncology Reports
TRAIL‑R2 (DR5), one of the death receptors, can activate the extrinsic apoptosis pathway, while cellular FLICE‑inhibitory protein (c‑FLIP) can inhibit this pathway. Both of them play important roles in the occurrence and development of most tum
Publikováno v:
Oncology Reports
Metastasis‑associated lung adenocarcinoma transcript 1 (MALAT1) is a long non‑coding RNA that is overexpressed in various human cancers, including breast cancer. Evidence has associated the function of the α‑2,8‑sialyltransferase (ST8SIA) fa
Autor:
Natalia Glatzel-Plucinska, Piotr Dziegiel, Adam Rzechonek, Aleksandra Piotrowska, Marzenna Podhorska-Okolow
Publikováno v:
Oncology Reports
Lung cancer is one of the most frequently diagnosed neoplasms and the leading cause of cancer‑related mortality worldwide. Its predominant subtype is non‑small cell lung cancer (NSCLC), which accounts for over 80% of the cases. Surprisingly, the
Autor:
Cuimeng Tian, Jianhui Li, Ji Ming Wang, Teng Ma, Jiaqiang Huang, Shuye Lin, Keqiang Chen, Bin Liu, Wanghua Gong
Publikováno v:
Oncology Reports
Disruption in mucins (MUCs) is involved in cancer development and metastasis and is thus used as a biomarker. Non-small cell lung carcinoma (NSCLC) is characterized by heterogeneous genetic and epigenetic alterations. Lung adenocarcinoma (LUAD) and s
Publikováno v:
Oncology Reports
Alternative mRNA splicing (AS) contributes greatly to expanding the diversity and function of the proteome. Increasing evidence has suggested that dysregulation of mRNA splicing may be associated with various types of cancer. In the present study, RN
Publikováno v:
Oncology Reports
Epithelial-mesenchymal transition (EMT) is a critical step in the acquisition of metastatic and invasive power for tumor cells. Colorectal adenocarcinoma (CRC) is a common cancer where metastasis is directly linked to patient survival. Recent studies
Publikováno v:
Oncology Reports
Colorectal cancer (CRC) has one of the highest mortality rates in the worldwide and its incidence has been increasing in recent years. Protein tyrosine kinase-7 (PTK7) is an inactive member of receptor protein tyrosine kinase (RPTK)-like molecules, w
Publikováno v:
Oncology Reports
Aberrant expression of argininosuccinate synthetase (ASS1, also known as ASS) has been found in cancer cells and is involved in the carcinogenesis of gastric cancer. The aim of the present study was to investigate the level of ASS expression in human
Autor:
Hisafumi Kinoshita, Toru Hisaka, Hiroyuki Horiuchi, Akihiko Kawahara, Ryuichi Kawahara, Shinji Uchida, Hirohisa Yano, Yoshiki Naito, Yusuke Ishida, Masamichi Nakayama, Yoshinobu Okabe, Hiroto Ishikawa, Masanori Akashi, Kazuo Shirozu, Tomoki Taira, Masayoshi Kage, Kazuhiro Mikagi, Yusuke Kawashima
Publikováno v:
Oncology Reports
We classified resected intraductal papillary mucinous neoplasms (IPMNs) into four subtypes (gastric, intestinal, pancreatobiliary and oncocytic) according to their morphological features and mucin expression, determined their clinicopathological char