Zobrazeno 1 - 10
of 246
pro vyhledávání: ''
Autor:
Thomas Wolfram Paul Friedl, Wolfgang Janni, Davut Dayan, Amelie de Gregorio, Jens Huober, Nikolaus de Gregorio, Eva Hering, Peter Widschwendter, Inga Bekes
Publikováno v:
Oncology. 99:780-789
Introduction: Ki67 as a proliferative marker has prognostic and therapeutic relevance in early breast cancer (EBC). However, standard cutoffs for distinguishing low and high Ki67 do not exist. Material and Methods: Data from all patients treated at t
Autor:
Francesca Platini, Alba Bianco, Carlo Resteghini, Donata Galbiati, Massimo Milione, Cristiana Bergamini, Paolo Bossi, Lisa Licitra, Salvatore Alfieri, Stefano Cavalieri, Federica Perrone, Laura D. Locati
Publikováno v:
Oncology. 97:112-118
Background: Recurrent or metastatic (R/M) skin squamous cell carcinoma (sSCC) not amenable of surgery or irradiation may benefit from systemic therapies. Epidermal growth factor receptor (EGFR) inhibitors and, more recently, immune checkpoint blocker
Publikováno v:
Oncology. 98(12)
Background: Circulating tumor cells (CTCs) have been identified and shown to have prognostic and predictive roles in several types of carcinoma. More recently, aneuploid CTCs have become subject of a growing interest, as aneuploidy is considered a ha
Autor:
Kazuto Harada, Jeffrey H. Lee, Mariela A. Blum Murphy, Manoop S. Bhutani, Irene Thomas, Dilsa Mizrak Kaya, Graciela M. Nogueras González, Jane E. Rogers, Brian Weston, Jaffer A. Ajani, Prajnan Das, Brian D. Badgwell
Publikováno v:
Oncology. 98(8)
Background: Preoperative induction chemotherapy followed by chemoradiation yields better R0 resection rates, pathologic complete response (pCR) rates and improved survival for localized gastric adenocarcinoma (GAC). We report the effect of three-drug
Publikováno v:
Oncology. 94(4):233-242
Objective: The aim of this study was to characterize the expression of hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12), an enzyme involved in the synthesis of arachidonic acid (AA), in ovarian cancer, and to study its coexpression with its ups
Autor:
Masashi Takano, Kento Kato, Hiroki Ishibashi, Junko Hirata, Tadashi Aoyama, Hideki Iwahashi, Morikazu Miyamoto, Hitoshi Tsuda, Hiroaki Soyama, Hiroko Matuura, Tomoyuki Yoshikawa, Ayako Suzuki, Kenichi Furuya
Publikováno v:
Oncology. 93:29-35
Objective: Most of the endometrial carcinomas are detected in early stages and have a better prognosis; however, predictive factors for recurrence have not been determined. Methods: Patients with grade 1 endometrioid carcinoma (EG1) according to the
Autor:
Maria Blettner, Rolf Kreienberg, Catharina Bartmann, Mathias Krockenberger, Achim Wöckel, J Diessner, Sebastian Häusler, Tanja Stüber, I. Novopashenny, Manfred Wischnewsky, Roland Stein, Wolfgang Janni
Publikováno v:
Oncology. 92:317-324
Objective: To identify subgroups of patients with pT1 pN0 breast cancer (BC) who might not profit from adjuvant systemic therapy (AST). Methods: Data of 3,774 pT1 pN0 BC patients from 17 certified BC centres within the BRENDA study group were collect
Publikováno v:
Oncology. 93:122-126
Objective: The aim of this study was to evaluate disease-specific survival and cost related to radioactive iodine therapy (RAI) utilization in patients with early-stage papillary thyroid carcinoma (PTC). Methods: This was a retrospective cohort study
Publikováno v:
Oncology. 92:190-196
Background: Although squamous cell anal carcinomas are relatively rare, their incidence has been increasing steadily. Because of the limited data, treatment of metastatic disease is a major therapeutic challenge. In this study, we report the safety a
Autor:
Tomoko So, Soichi Oka, Hidetaka Uramoto, Masaru Takenaka, Takeshi Hanagiri, Sohsuke Yamada, Akihiro Taira, Shinji Shinohara, Yasuhiro Chikaishi, Fumihiro Tanaka
Publikováno v:
Oncology. 90:327-338
Background/Objectives: CD44 is often expressed in various types of tumor cells and involved in a number of biological behaviors of malignancy. The present study focused on the clinical significance of the expression of CD44st and CD44v6 in non-small