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Autor:
Kazuaki Okamoto, Hiroaki Nozawa, Shigenobu Emoto, Koji Murono, Kazuhito Sasaki, Soichiro Ishihara
Publikováno v:
Oncology. 100:576-582
Introduction: Adjuvant chemotherapy improves the prognosis of patients with colorectal cancer (CRC) following radical resection. However, the safety and efficacy of oxaliplatin-based chemotherapeutic regimens for elderly patients remains to be elucid
Autor:
Hidetoshi Yasuoka, Atsushi Naganuma, Eishin Kurihara, Tsutomu Kobatake, Masashi Ijima, Yuki Tamura, Yuhei Suzuki, Takashi Hoshino, Fumiya Ishida, Hisashi Hosaka, Takeshi Hatanaka, Sachiko Yoshida, Ryusuke Aihara, Yasuo Hosouchi, Norihiro Ishii, Kenichiro Araki, Ken Shirabe, Toshio Uraoka, Satoru Kakizaki
Publikováno v:
Oncology. 100:449-459
Introduction: This retrospective study investigated the efficacy and safety of nano-liposomal irinotecan (nal-IRI) plus 5-fluorouracil/L-leucovorin (5-FU/l-LV) treatment in the second-line or later setting for advanced pancreatic cancer under real-wo
Autor:
Mohammed B. Allaw, Jeffrey M. Switchenko, Lana Khalil, Christina Wu, Olatunji B. Alese, Mehmet Akce, Amber Draper, Aaron T. Jones, Bassel El-Rayes, Walid Shaib
Publikováno v:
Oncology
Background: The 2 approved somatostatin analogs (SSAs) in the first-line treatment of advanced, well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are octreotide long-acting release (Sandostatin LAR) and somatuline depot (Lan
Autor:
Takahito Negishi, Akira Matsunobu, Makoto Endo, Ryouhei Yokoyama, Shuhei Kusano, Nobuki Furubayashi, Kenichi Taguchi, Yoshiyuki Shioyama, Keiichiro Iida, Toshifumi Fujiwara, Nokitaka Setsu, Yoshihiro Matsumoto, Yasuharu Nakashima, Kenichi Kohashi, Hidetaka Yamamoto, Yoshinao Oda, Motonobu Nakamura
Publikováno v:
Oncology. 100:148-154
Introduction: Radiation-associated sarcoma (RAS) is one of the most life-threatening complications associated with the treatment of malignant neoplasms. Because all RAS patients have a history of radiotherapy, there have been no effective treatment o
Publikováno v:
Oncology. 100:155-162
Introduction: Not only the 21-gene recurrence score (RS) assay but also online prognostic tools and immunohistochemical prognostic models predict chemotherapy benefits for women with early breast cancer (BC). Multigene assays, including Oncotype DX,
Autor:
Tadashi Shiraishi, Takeshi Toyozumi, Haruhito Sakata, Kentaro Murakami, Masayuki Kano, Yasunori Matsumoto, Masaya Yokoyama, Koichiro Okada, Toshiki Kamata, Takahiro Ryuzaki, Kazuya Kinoshita, Soichiro Hirasawa, Hisahiro Matsubara
Publikováno v:
Oncology. 100:39-47
Introduction: We determined the soluble programmed cell death-1 ligand-1 (sPD-L1) concentration in patients with esophageal squamous cell carcinoma (ESCC), and confirmed the PD-L1 expression in resected specimens. Methods: Blood samples were collecte
Autor:
Atsushi Naganuma, Takaaki Tanaka, Atsushi Hiraoka, Satoshi Yasuda, Kazuya Kariyama, Noritomo Shimada, Shinichiro Nakamura, Satoru Kakizaki, Michitaka Imai, Koichi Takaguchi, Takuya Nagano, Toshifumi Tada, Akemi Tsutsui, Takashi Kumada, Takeshi Hatanaka, Kazuhiro Nouso, Toru Ishikawa, Kunihiko Tsuji, Hidenori Toyoda, Hiroshi Shibata, Ei Itobayashi
Publikováno v:
Oncology
Background/Aim: With the development of systemic treatment methods for unresectable hepatocellular carcinoma (uHCC), the concept of unsuitable for transcatheter arterial chemoembolization (TACE) has become important. This study aimed to establish a s
Autor:
Ines Beilmann-Lehtonen, Ulf-Håkan Stenman, Caj Haglund, Tuomas Kaprio, Kajsa Björkman, Camilla Böckelman
Publikováno v:
Oncology. 100:22-30
Objectives: Colorectal cancer is the third most common cancer worldwide, with an obvious need for more accurate prognostics. Previous studies identified C-reactive protein (CRP) as a prognostic serum biomarker for colorectal cancer, whereas the bioma
Autor:
Mariko Kobayashi, Satoshi Saitoh, Nozomu Muraishi, Masahiro Kobayashi, Fumitaka Suzuki, Kenji Ikeda, Norio Akuta, Yasuji Arase, Shunichiro Fujiyama, Hiromitsu Kumada, Tetsuya Hosaka, Hitomi Sezaki, Yusuke Kawamura, Yoshiyuki Suzuki
Publikováno v:
Oncology
Introduction: It is unclear whether the relationships between changes in fibrosis and circulating microRNA-122 (miR-122) dynamics might influence the prognosis of nonalcoholic fatty liver disease (NAFLD). Methods: This study investigates the impact o
Autor:
Masaki Mori, Yoshihiro Matsumoto, Yuki Ando, Koshi Mimori, Akihiro Kitagawa, Taro Tobo, Takaaki Masuda, Yusuke Nakano, Yuta Kobayashi, Junichi Takahashi, Tadashi Abe, Tomoharu Yoshizumi, Keisuke Kosai
Publikováno v:
Oncology. 100:101-113
Introduction: Fanconi anemia complementation group E (FANCE) is a Fanconi anemia (FA) pathway gene that regulates DNA repair. We evaluated the clinical relevance of FANCE expression in hepatocellular carcinoma (HCC). Methods: First, the associations