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Autor:
Kazuto Nishio, Soichi Fumita, Kazuhiko Nakagawa, Junko Tanizaki, Isamu Okamoto, Wataru Okamoto
Publikováno v:
Oncogene. 30:4097-4106
Lapatinib, a dual tyrosine kinase inhibitor of the epidermal growth factor receptor and human epidermal growth factor receptor 2 (HER2), is clinically active in patients with breast cancer positive for HER2 amplification. The mechanism of this anti-t