Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andres J. Klein-Szanto"'
Autor:
Koji Tanaka, Yoshiaki Kita, Jeffrey D. Winkler, Andres J. Klein-Szanto, Douglas S. Darling, Hiroshi Nakagawa, Satish Srinivasan, Manti Guha, Anil K. Rustgi, Ravi K. Amaravadi, Narayan G. Avadhani, Kelly A. Whelan, Mitsuteru Natsuizaka, Prasanna M. Chandramouleeswaran, Shoji Natsugoe
Publikováno v:
Oncogene
High CD44 expression is associated with enhanced malignant potential in esophageal squamous cell carcinoma (ESCC), among the deadliest of all human carcinomas. Although alterations in autophagy and CD44 expression are associated with poor patient out
Autor:
Andres J. Klein-Szanto, Elizabeth P. Henske, Tiffiney R. Hartman, Emmanuelle Nicolas, Tahseen Al-Saleem, T P Cash, M. C. Simon
Publikováno v:
Oncogene. 28:1594-1604
Birt-Hogg-Dubé (BHD) syndrome is a tumor-suppressor gene disorder characterized by skin tumors, cystic lung disease and renal cell carcinoma. Very little is known about the molecular pathogenesis of BHD. Clinical similarities between BHD and tuberou
Autor:
Anil K. Rustgi, Sabrina Kim, Munenori Takaoka, Kenji Oyama, Wafik S. El-Deiry, Meenhard Herlyn, Claudia D. Andl, Andres J. Klein-Szanto, Hiroshi Nakagawa, J A Diehl, Takaomi Okawa
Publikováno v:
Oncogene. 26:2353-2364
Epidermal growth factor receptor (EGFR) overexpression and activation is critical in the initiation and progression of cancers, especially those of epithelial origin. EGFR activation is associated with the induction of divergent signal transduction p
Autor:
Lawrence C. Kenyon, Andres J. Klein-Szanto, Alfredo Fusco, Carlo M. Croce, Ivana De Martino, Rosa Visone, Gustavo Baldassarre, Francesca Pentimalli, Andrea Ciarmiello, Monica Fedele, Giuseppe Viglietto, Sabrina Battista, Claudio Arra
Publikováno v:
Oncogene (Basingstoke) 24 (2005): 3427–3435. doi:10.1038/sj.onc.1208501
info:cnr-pdr/source/autori:Fedele M; Pentimalli F; Baldassarre G; Battista S; Klein-Szanto AJ; Kenyon L; Visone R; De Martino I; Ciarmiello A; Arra C; Viglietto G; Croce CM; Fusco A./titolo:Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone%2Fprolactin cell pituitary adenomas and natural killer cell lymphomas./doi:10.1038%2Fsj.onc.1208501/rivista:Oncogene (Basingstoke)/anno:2005/pagina_da:3427/pagina_a:3435/intervallo_pagine:3427–3435/volume:24
info:cnr-pdr/source/autori:Fedele M; Pentimalli F; Baldassarre G; Battista S; Klein-Szanto AJ; Kenyon L; Visone R; De Martino I; Ciarmiello A; Arra C; Viglietto G; Croce CM; Fusco A./titolo:Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone%2Fprolactin cell pituitary adenomas and natural killer cell lymphomas./doi:10.1038%2Fsj.onc.1208501/rivista:Oncogene (Basingstoke)/anno:2005/pagina_da:3427/pagina_a:3435/intervallo_pagine:3427–3435/volume:24
Overexpression of HMGA1 proteins is a constant feature of human carcinomas. Moreover, rearrangements of this gene have been detected in several human benign tumors of mesenchymal origin. To define the role of these proteins in cell transformation in
Autor:
Mitsuteru Natsuizaka, Phyllis A. Gimotty, Devraj Basu, Andres J. Klein-Szanto, Nicole D. Facompre, Ann Marie Egloff, Shingo Kagawa, Anil K. Rustgi, Seiji Naganuma, J A Diehl, Kelly A. Whelan, Kwok K. Wong, Shinya Ohashi, Hiroshi Nakagawa, Hideaki Kinugasa, Adam J. Bass
Publikováno v:
Oncogene
Notch activity regulates tumor biology in a context-dependent and complex manner. Notch may act as an oncogene or a tumor-suppressor gene even within the same tumor type. Recently, Notch signaling has been implicated in cellular senescence. Yet, it r
Autor:
R. S. Yeung, Guang-Hui Xiao, A E Kisielewski, Shao-Chen Liu, K Bleicher, Tamra L. Goodrow, J Sina, Andres J. Klein-Szanto, M Novara
Publikováno v:
Oncogene. 17:83-91
The FHIT gene has been implicated as a tumor suppressor gene in human malignancies. To determine if FHIT alterations play a role in human squamous cell carcinogenesis of the head and neck (HNSCC), we examined the gene and its product by RT-PCR, SSCP,
Autor:
Caitlin G. Howe, Fang Xiao, Andres J. Klein-Szanto, Xiang Hua, Denise C. Connolly, Thuy-Vy Do, Shane W. O'Brien, Harsh B. Pathak, Samuel Litwin, Andrew K. Godwin, Marisa A. Maglaty, Laura E. Bickel, Russell J. Schilder, Jeffrey Ecsedy, Erica A. Golemis
Publikováno v:
Oncogene. 33(5)
Aurora kinase A (AURKA) localizes to centrosomes and mitotic spindles where it mediates mitotic progression and chromosomal stability. Overexpression of AURKA is common in cancer, resulting in acquisition of alternate non-mitotic functions. In the cu
Autor:
Maria Shubina, Victoria Serzhanova, Mineo Kurokawa, Sachiko Seo, Brian L. Egleston, Joy L. Little, Grace Loudon, Andres J. Klein-Szanto, Eugene Izumchenko, Michael F. Ochs, Erica A. Golemis, Erica Parise
Publikováno v:
Oncogene. 33(4)
Overexpression of the NEDD9/HEF1/Cas-L scaffolding protein is frequent, and drives invasion and metastasis in breast, head and neck, colorectal, melanoma, lung and other types of cancer. We have examined the consequences of genetic ablation of Nedd9
Autor:
Karl-Heinz Braunewell, Andres J. Klein-Szanto, Anatilde M Gonzalez Guerrico, Jonathan Chernoff, Robert E. Page, Zahara M. Jaffer
Publikováno v:
Oncogene. 24(14)
Tumor cell invasion is a highly integrated and complex process comprising several biologically distinct functions such as cell adhesion, motility, proteolysis, etc. Visinin-like protein-1 (VILIP-1), a member of the neuronal EF-hand calcium-sensor pro
Autor:
Kristine L Skele, Deborah A. Altomare, Joseph R. Testa, Hui Qin Wang, Assunta De Rienzo, Andres J. Klein-Szanto, Andrew K. Godwin
Publikováno v:
Oncogene. 23(34)
Activation of the PI3K/AKT pathway may contribute to tumorigenesis. AKT mediates survival signals that protect cells from apoptosis and, thus, is a potentially important therapeutic target. To determine the frequency of AKT activation in human ovaria