Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dan Li"'
Autor:
Shouhai Zhu, Chunjun Zhao, Han Liu, Ting Kang, Zhenshu Xu, Yan Sun, Zhi Qiao, Shuhong Shen, Maolin Ge, Shifen Wang, Dan Li, Hua Xiao
Publikováno v:
Oncogene
MLL undergoes multiple distinct chromosomal translocations to yield aggressive leukemia with dismal outcomes. Besides their well-established role in leukemogenesis, MLL fusions also possess latent tumor-suppressive activity, which can be exploited as
Publikováno v:
Oncogene. 40(3)
The key component in the UFM1 conjugation system, UFM1-binding and PCI domain-containing protein 1 (UFBP1), regulates many biological processes. Recently it has been shown that low UFBP1 protein level is associated with the worse outcome of gastric c
Autor:
Dong M. Shin, Dan Li, Yibin Kang, Chaoyun Pan, Kelly R. Magliocca, Jaemoo Chun, Sumin Kang, Gina N. Alesi, Zhuo Georgia Chen, Jun Fan, Fadlo R. Khuri, Lingtao Jin
Publikováno v:
Oncogene. 36:3797-3806
Metastases remain the major cause of death from cancer. Recent molecular advances have highlighted the importance of metabolic alterations in cancer cells, including the Warburg effect that describes an increased glycolysis in cancer cells. However,
Autor:
Liduan Zheng, Xiang Zhao, Dehua Yang, Qiangsong Tong, Hong Mei, Jiarui Pu, Kun Huang, Hongxia Qu, Xuan Xiang, Dan Li
Publikováno v:
Oncogene. 35:3565-3576
Previous studies have indicated the important roles of MYCN in tumorigenesis and progression of neuroblastoma (NB), the most common extracranial solid tumor derived from neural crest in childhood. However, the regulatory mechanisms of MYCN expression
Autor:
Karen L. Wendt, Laura A. Augustine, Emily C. Sibala, Shane R. Stecklein, Sumedha Gunewardena, Roy A. Jensen, Easwari Kumaraswamy, Dan Li
Publikováno v:
Oncogene. 34:4333-4346
Breast cancer 1 (BRCA1)-associated breast cancers are mostly basal-like high-grade ductal carcinomas that frequently overexpress epidermal growth factor receptor (EGFR). Aberrant EGFR expression is correlated with disease progression, resistance to r
Autor:
Yajun Chen, Huajie Song, Hong Mei, Kai Huang, Xiaojing Wang, Wanju Jiao, Qiangsong Tong, Dan Li, Feng Yang, Erhu Fang, Liduan Zheng
Publikováno v:
Oncogene. 37(20)
Recent studies reveal the emerging functions of enhancer RNAs (eRNAs) in gene expression. However, the roles of eRNAs in regulating the expression of heparanase (HPSE), an established endo-β-D-glucuronidase essential for cancer invasion and metastas
Autor:
Yajun Chen, Kai Huang, Liduan Zheng, Xiaojing Wang, Wanju Jiao, Huajie Song, Qiangsong Tong, Feng Yang, Erhu Fang, Dan Li, Ye Lin, Hong Mei
Publikováno v:
Oncogene
Emerging studies have indicated the essential functions of long noncoding RNAs (lncRNAs) during cancer progression. However, whether lncRNAs contribute to the upregulation of v-ets erythroblastosis virus E26 oncogene homolog 1 (Ets-1), an established
Autor:
Zhongwei Lv, Dan Li, Yu-Shui Ma, Cheng-You Jia, Bo Wu, Xianzhao Deng, Youben Fan, Xiao-Ping Zhang, Haidong Cai, Lin Liu
Publikováno v:
Oncogene
Anaplastic thyroid cancer (ATC) is associated with poor prognosis and is often untreatable. MicroRNA 483-3p (miR-483) and partitioning-defective 3 (Pard3), a member of the Pard family, have functions and regulatory mechanisms in ATC. The abnormal reg
Autor:
Wen Jun Zhou, Dan Dan Li, Jun Tang, Yi Xin Zeng, Guo Kai Feng, Jun Ma, Shu-Na Chen, R. Deng, Xiao Feng Zhu, Liang Ping Xia
Publikováno v:
Oncogene. 30:944-955
An elevated DNA-repair capacity in cancer cells leads to radiation resistance and severely limits the efficacy of radiation therapy. Activation of Akt is tightly associated with resistance to radiotherapy, and Mre11 protein has important role during
Publikováno v:
Oncogene. 35(25)
Because malignant cells have altered, usually accelerated, energy consumption, targeting metabolic signaling represents a prevailing strategy for tumor therapy. Phosphoinositide-dependent kinase 1 (PDK1) is a proximal signaling molecule of phosphatid