Zobrazeno 1 - 10
of 19
pro vyhledávání: ''
Autor:
Keltouma Driouch, Sandra Geraci, Michele Iuliani, Philippe Clézardin, Martine Croset, Bruno Vincenzi, Klaus Pantel, Francesco Pantano, Giulia Ribelli, Natalia Bednarz-Knoll, Edith Bonnelye, Daniele Santini, Giuseppe Tonini, Harriet Wikman, Florian Bonin, Sofia Sousa, Saw See Hong, Sonia Simonetti
Publikováno v:
Oncogene
Oncogene, In press, ⟨10.1038/s41388-020-01603-6⟩
Oncogene, Nature Publishing Group, In press, ⟨10.1038/s41388-020-01603-6⟩
Oncogene, In press, ⟨10.1038/s41388-020-01603-6⟩
Oncogene, Nature Publishing Group, In press, ⟨10.1038/s41388-020-01603-6⟩
Bone metastasis remains a major cause of mortality and morbidity in breast cancer. Therefore, there is an urgent need to better select high-risk patients in order to adapt patient’s treatment and prevent bone recurrence. Here, we found that integri
Autor:
Elinor Löverli, Joel S. Parker, Charles M. Perou, Arian Lundberg, Jonas Bergh, Nicholas P. Tobin, Linda S. Lindström
Publikováno v:
Oncogene
BackgroundPan-cancer genomic analyses based on the magnitude of pathway activity are currently lacking. Focusing on the cell cycle, we examined the DNA mutations and chromosome arm-level aneuploidy within tumours with low, intermediate and high cell
Autor:
W. Samantha N. Jayasekara, Beena Kumar, Emily Stone, Venessa T. Chin, Mark J. Cowley, Rachael A. McCloy, Alvaro Gonzalez-Rajal, Prudence A. Russell, Jason E. Cain, Tracy L. Leong, Anthony T. Papenfuss, Daniel P Steinfort, Muhammad Alamgeer, Louis Irving, Velimir Gayevskiy, Fernando J. Rossello, Marshall Plit, Daniel J. Gough, Vishal Boolell, Andrew S. Field, D. Neil Watkins, Marie Liesse Asselin-Labat, Adrian Havryk, Kieren D. Marini, Vinod Ganju, Marc R. De Massy, Anette Szczepny, Barton R Jennings
Publikováno v:
Oncogene
Our understanding of genomic heterogeneity in lung cancer is largely based on the analysis of early-stage surgical specimens. Here we used endoscopic sampling of paired primary and intrathoracic metastatic tumors from 11 lung cancer patients to map g
Autor:
Vary Shahryari, Z. L. Tabatabai, Guoren Deng, Rajvir Dahiya, Thao Ly Yang, Yuichiro Tanaka, Kirandeep Sekhon, Soichiro Yamamura, Sharanjot Saini, Shahana Majid, Yozo Mitsui, Christine L. Hsieh, Nathan Bucay, George A. Calin
Publikováno v:
Oncogene
A major genomic alteration in prostate cancer (PCa) is frequent loss of chromosome (chr) 8p with a common region of loss of heterozygosity (LOH) at chr8p22 locus. Genomic studies implicate this locus in the initiation of clinically significant PCa an
Publikováno v:
Oncogene
Our previous studies demonstrated that Jab1/Csn5 overexpression is correlated with low survival rates in cancer patients, including nasopharyngeal carcinoma (NPC), breast cancer and hepatocellular carcinoma, and contributes to NPC's resistance to rad
Autor:
Daoyan Wei, Ming Quan, Keping Xie, Dacheng Xie, Tian Xia, Zhiliang Jia, Jiujie Cui, Yong Gao, Suyun Huang, Liang Wang
Publikováno v:
Oncogene
Purpose Hepatocyte growth factor (HGF)/Met signaling plays critical roles in pancreatic ductal adenocarcinoma (PDA) development and progression and is considered a potential therapeutic target for this disease. However, the mechanism of aberrant acti
Autor:
Zhiqiang Qin, Augusto C. Ochoa, Luis Del Valle, Denise Whitby, Lu Dai, Erik K. Flemington, Wendell Miley
Publikováno v:
Oncogene
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of several human cancers such as Kaposi's sarcoma (KS), which represents the most common AIDS-associated malignancy that lacks effective treatment options. Despite its clear role i
Autor:
Josep M. Llovet, Augusto Villanueva, Sebastiao N. Martins-Filho, M. Isabel Fiel, Johann von Felden, Myron Schwartz, Carlos Villacorta-Martin, Amanda J. Craig, Milind Mahajan, Delia D'Avola, Ashley Stueck, Swan N. Thung, Ismail Labgaa, Parissa Tabrizian, Stephen C. Ward, Daniela Sia, Scott L. Friedman, Celina Ang
Publikováno v:
Oncogene
Cellular components of solid tumors including DNA are released into the bloodstream, but data on circulating-free DNA (cfDNA) in hepatocellular carcinoma (HCC) are still scarce. This study aimed at analyzing mutations in cfDNA and their correlation w
Autor:
Peter Truesdell, Jalna Meens, Joseph Ahn, Kathleen Watt, Harish Chander, Andrew W.B. Craig, Xiaolong Yang
Publikováno v:
Oncogene
Aberrant epidermal growth factor receptor (EGFR) signaling in non-small cell lung cancer (NSCLC) is linked to tumor progression, metastasis and poor survival rates. Here we report the role of Cdc42-interacting protein 4 (CIP4) in the regulation of NS
Publikováno v:
Oncogene
The orphan nuclear receptor TR3 (NR41A and Nur77) is overexpressed in most lung cancer patients and is a negative prognostic factor for patient survival. The function of TR3 was investigated in non-small-cell lung cancer A549 and H460 cells, and knoc