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Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner
Autor:
Jessica R Doll, Claire A. Chougnet, Traci E. Stankiewicz, Maria E. Moreno-Fernandez, Vishakha Sharma, Jarren R Oates, Senad Divanovic, Maha Almanan, David A. Hildeman, Michelle S M A Damen
Publikováno v:
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-13 (2021)
Nutrition & Diabetes
Nutrition & Diabetes
Background Understanding gender-associated bias in aging and obesity-driven metabolic derangements has been hindered by the inability to model severe obesity in female mice. Methods Here, using chow- or high fat diet (HFD)-feeding regimens at standar
Autor:
Chun Liang, Changyu Li, Man Hei Cheung, Yu Dong, Meiai Lin, Yitao Chen, Wenjun Xu, Zhongxia Lu, Xin Wang
Publikováno v:
Nutrition & Diabetes, Vol 10, Iss 1, Pp 1-12 (2020)
Nutrition & Diabetes
Nutrition & Diabetes
Objectives The study aimed to examine the anti-diabetic effects of Gynura divaricata (GD) and the underlying mechanism. Methods Information about the chemical compositions of GD was obtained from extensive literature reports. Potential target genes w
Publikováno v:
Nutrition & Diabetes, Vol 10, Iss 1, Pp 1-11 (2020)
Nutrition & Diabetes
Nutrition & Diabetes
Backgrounds Mitochondria plays a critical role in the development and pathogenesis of nonalcoholic fatty liver disease (NAFLD). Neohesperidin (NHP) could lower blood glucose and prevent obesity in mice. However, the direct effect of NHP on hepatic st
Publikováno v:
Nutrition & Diabetes, Vol 8, Iss 1, Pp 1-8 (2018)
Nutrition & Diabetes
Nutrition & Diabetes
OBJECTIVE Through dynamic means, etiological factors, including chronic inflammation and insulin resistance have the potential to perpetuate metabolic incidences such as type 2 diabetes and obesity. Abatement of such syndromes can be achieved by comp