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Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 33:455-465
Glut9 is highly expressed in the human kidney proximal convoluted tubular and plays a crucial role in the regulation of plasma urate levels. The gene effects were stronger among women. Our results show that 17-β-estradiol (E2) through ER (estrogen r
Autor:
Iwona Pelikant-Malecka, R. T. Smolenski, Mariola Olkowicz, Ewa M. Slominska, Małgorzata Swiatkowska-Freund, Ewa Kaniewska, Krzysztof Preis, Alicja Sielicka, Magdalena M. Gorska, Zofia Pankrac
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 33:342-346
Mechanisms of free radical injury involve chemical modification of proteins, lipid derivatives and nucleic acids and consequent loss of its function. However, specific targets and exact sequence of events has not been fully clarified. We determined w
Autor:
Irene V. Bijnsdorp, G.J. Peters
Publikováno v:
Bijnsdorp, I V & Peters, G J 2011, ' Deoxyribose protects against rapamycin-induced cytotoxicity in colorectal cancer cells in vitro ', Nucleosides, Nucleotides and Nucleic Acids, vol. 30, no. 12, pp. 1197-1202 . https://doi.org/10.1080/15257770.2011.602657
Nucleosides, Nucleotides and Nucleic Acids, 30(12), 1197-1202. Taylor and Francis Ltd.
Nucleosides, Nucleotides and Nucleic Acids, 30(12), 1197-1202. Taylor and Francis Ltd.
Thymidine phosphorylase (TPase) is also known as the platelet-derived endothelial cell growth factor (PD-ECGF) and plays a role in angiogenesis. Deoxyribose (dR; a downstream TPase-product) addition to endothelial cells may stimulate FAK and p70/S6k
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids
RNA interference (RNAi) mediated by siRNAs has proved to be a highly effective gene silencing mechanism with great potential for gene therapeutic applications. However, siRNA agents have been shown to exert non-target-related biological effects and t
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 25:1119-1123
Upregulated expression of eN has been found in the highly invasive human melanoma cell lines but neither in melanocytes nor in primary tumor cells. Membrane proteins associated with cell adhesion and metastasis: alpha5-, beta1-, beta3-integrins, and
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 25:1277-1281
B-cell chronic lymphocytic leukemia (B-CLL) is an adult-onset highly heterogeneous malignancy characterized by a cells resistance to apoptosis rather than to highly proliferative cells. In previous research, we evidenced an imbalance of purine metabo
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 25:1125-1128
Endothelial degradation of extracellular nucleotides is known to be an important mechanism in regulation of thrombosis, inflammation and immune response. It is possible that this pathway is a target for pleiotropic drugs such as atorvastatin. We stud
Autor:
Ann Saada-Reisch
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 23:1205-1215
Mitochondrial DNA (mtDNA) depletion syndromes (MDS) are a heterogeneous group of mitochondrial disorders, manifested by a decreased mtDNA copy number and respiratory chain dysfunction. Primary MDS are inherited autosomally and may affect a single org
Autor:
Valentin V. Vlassov, Evgeniy S. Morozkin, Pavel P. Laktionov, Elena Yu. Rykova, Olga E. Bryzgunova
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 23:927-930
Extracellular nucleic acids in cultures of A431 and HeLa cells were investigated. The data obtained demonstrate the presence of high weight DNA and RNA in the extracellular medium. Temporal changes of extracellular nucleic acids levels in growth medi
Autor:
Floyd F. Snyder, Stephen D. Hodges
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 23:1269-1274
A media has been developed which enables the assessment of mitochondrial function in fibroblasts by measuring proliferation as an end point.