Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cheryl H. Arrowsmith"'
Autor:
Aiping Dong, Levon Halabelian, Cheryl H. Arrowsmith, Yanjun Li, Ute Kothe, Hong Zeng, Hong Wu, Julia Guegueniat
Publikováno v:
Nucleic Acids Research
Nucleic Acids Res
Nucleic Acids Res
The human pseudouridine synthase PUS7 is a versatile RNA modification enzyme targeting many RNAs thereby playing a critical role in development and brain function. Whereas all target RNAs of PUS7 share a consensus sequence, additional recognition ele
Autor:
Panagis Filippakopoulos, Dalia Barsyte-Lovejoy, Edyta Marcon, Elizabeth Henderson, Cheryl H. Arrowsmith, Jack Greenblatt, Ashley Hutchinson, Levon Halabelian, Alma Seitova, Danton Ivanochko, Pavel Savitsky, Evelyne Lima-Fernandes, Harshika Jain, Shili Duan
Publikováno v:
Nucleic Acids Research
Aberrant isoform expression of chromatin-associated proteins can induce epigenetic programs related to disease. The MDS1 and EVI1 complex locus (MECOM) encodes PRDM3, a protein with an N-terminal PR-SET domain, as well as a shorter isoform, EVI1, lac
Autor:
Jun Ding, Zhen Han, Cheryl H. Arrowsmith, Zhesi Zhu, Xiangkun Yang, Nawei Zhang, Minkui Luo, Jiabao Song, Hong Zeng, Levon Halabelian, Michael G. Bartlett, Maomao He, Yingming Zhao, Liza Ngo, Y. George Zheng
Publikováno v:
Nucleic Acids Research
Short-chain acylations of lysine residues in eukaryotic proteins are recognized as essential posttranslational chemical modifications (PTMs) that regulate cellular processes from transcription, cell cycle, metabolism, to signal transduction. Lysine b
Autor:
Bothayna Al-Gashgari, Alaguraj Veluchamy, Lorena V. Cortés-Medina, Wolfgang Fischle, Zhadyra Yerkesh, Abrar Aljahani, Dulat Azhibek, Sarah Kreuz, Alexander Lemak, Scott Houliston, Papita Mandal, Lixin Fan, Shili Duan, Cheryl H. Arrowsmith, Maria Tauber, Michelle S. Ong
Publikováno v:
Nucleic Acids Research
UHRF1 is an important epigenetic regulator associated with apoptosis and tumour development. It is a multidomain protein that integrates readout of different histone modification states and DNA methylation with enzymatic histone ubiquitylation activi
Autor:
Ruedi Aebersold, Yong Wei, Scott Houliston, Xianyang Fang, Yun-Xing Wang, Lilia Kaustov, Cheryl H. Arrowsmith, Hong Zeng, Hong Wu, Lixin Fan, Fengling Li, Masoud Vedadi, Alexander Lemak, Marco Faini, Shili Duan, Abdellah Allali-Hassani
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 47 (17)
Nucleic Acids Research, 47 (17)
Histone H3K4 methylation is an epigenetic mark associated with actively transcribed genes. This modification is catalyzed by the mixed lineage leukaemia (MLL) family of histone methyltransferases including MLL1, MLL2, MLL3, MLL4, SET1A and SET1B. The
Autor:
Linda Z. Penn, Sara Helander, Veronika Csizmok, Jonas Carlsson, Patrik Lundström, Cecilia Andrésen, Julie D. Forman-Kay, Alexander Lemak, Christophe Farès, Maria Sunnerhagen, Cheryl H. Arrowsmith
Publikováno v:
Nucleic Acids Research
The crucial role of Myc as an oncoprotein and as a key regulator of cell growth makes it essential to understand the molecular basis of Myc function. The N-terminal region of c-Myc coordinates a wealth of protein interactions involved in transformati
Autor:
Abdellah Allali-Hassani, Yahong Guo, Masoud Vedadi, Chao Qi, Jinrong Min, Patricia W. Pan, Nataliya Nady, Matthieu Schapira, Maria F. Amaya, Cheryl H. Arrowsmith, Aiping Dong, Randy J. Read, Melanie A. Adams-Cioaba, Haizhong Zhu
Publikováno v:
Nucleic Acids Research
The MBT repeat has been recently identified as a key domain capable of methyl-lysine histone recognition. Functional work has pointed to a role for MBT domain-containing proteins in transcriptional repression of developmental control genes such as Ho
Autor:
Marc S. Wold, Michael A. Kennedy, Cheryl H. Arrowsmith, Garry W. Buchko, Gary W. Daughdrill, Maria Victoria Botuyan, David F. Lowry
Publikováno v:
Nucleic Acids Research. 31:4176-4183
Replication protein A (RPA) is a heterotrimeric single-stranded DNA- (ssDNA) binding protein that can form a complex with the xeroderma pigmentosum group A protein (XPA). This complex can preferentially recognize UV-damaged DNA over undamaged DNA and