Zobrazeno 1 - 10
of 15
pro vyhledávání: '"35"'
Autor:
Ayyappasamy Sudalaiyadum Perumal, Yangbo Hu, Rishi K. Vishwakarma, Konstantin Brodolin, Zakia Morichaud
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2018, 46 (19), pp.10106-10118. ⟨10.1093/nar/gky714⟩
Nucleic Acids Research, Oxford University Press, 2018, 46 (19), pp.10106-10118. ⟨10.1093/nar/gky714⟩
Nucleic Acids Research, 2018, 46 (19), pp.10106-10118. ⟨10.1093/nar/gky714⟩
Nucleic Acids Research, Oxford University Press, 2018, 46 (19), pp.10106-10118. ⟨10.1093/nar/gky714⟩
International audience; The transcriptional activator RbpA associates with Mycobacterium tuberculosis RNA polymerase (MtbRNAP) during transcription initiation, and stimulates formation of the MtbRNAP-promoter open complex (RPo). Here, we explored the
Autor:
Nikolay Zenkin, John Harbottle
Publikováno v:
Nucleic Acids Research
Bacterial RNA polymerase is a potent target for antibiotics, which utilize a plethora of different modes of action, some of which are still not fully understood. Ureidothiophene (Urd) was found in a screen of a library of chemical compounds for abili
Publikováno v:
Nucleic acids research. 22(12)
DNA sequences upstream of the rrnB P1 core promoter (-10, -35 region) increase transcription more than 300-fold in vivo and in vitro. This stimulation results from a cis-acting DNA sequence, the UP element, which interacts directly with the alpha sub
Publikováno v:
Nucleic acids research. 20(4)
Transcription from the Escherichia coli rrnB P1 promoter is increased by a cis-acting sequence which extends upstream of the -35 hexamer to about -150 with respect to the transcription initiation site, the Upstream Activation Region (UAR). Activation
Autor:
Paul J. J. Hooykaas, Paul Fransz, Bert J. van der Zaal, Beatrice I. Lindhout, Tobias Meckel, Federico Tessadori
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 35(16), e107
Nucleic Acids Research, 35(16), 1-9. Oxford University Press
Nucleic Acids Research, 35(16), e107
Nucleic Acids Research, 35(16), 1-9. Oxford University Press
Several techniques are available to study chromosomes or chromosomal domains in nuclei of chemically fixed or living cells. Current methods to detect DNA sequences in vivo are limited to trans interactions between a DNA sequence and a transcription f
Autor:
Lucy P. Eperon, Igor Vorechovsky, Robert Weinmeister, Jana Kralovicova, Li Chen, Andrew J. Hudson, Ian C. Eperon
Publikováno v:
Nucleic Acids Research
The selection of 3΄ splice sites (3΄ss) is an essential early step in mammalian RNA splicing reactions, but the processes involved are unknown. We have used single molecule methods to test whether the major components implicated in selection, the p
Autor:
Ekaterina A. Bogdanova, Sofia Medvedeva, Olga Pavlova, Marko Djordjevic, Max Nagornykh, Andjela Rodic, Konstantin Severinov, Evgeny Klimuk
Publikováno v:
Nucleic Acids Research
C-proteins control restriction–modification (R–M) systems’ genes transcription to ensure sufficient levels of restriction endonuclease to allow protection from foreign DNA while avoiding its modification by excess methyltransferase. Here, we ch
Autor:
Grace Yim, Peter Axerio-Cilies, Charles J. Thompson, George B. Spiegelman, Artem Cherkasov, Michael Hsing, Ján Burian
Publikováno v:
Nucleic Acids Research
Tuberculosis therapeutic options are limited by the high intrinsic antibiotic resistance of Mycobacterium tuberculosis. The putative transcriptional regulator WhiB7 is crucial for the activation of systems that provide resistance to diverse antibioti
Publikováno v:
Nucleic Acids Research
Transcription is initiated when RNA polymerase recognizes the duplex promoter DNA in the closed complex. Due to its transient nature, the closed complex has not been well characterized. How the initial promoter recognition occurs may offer important
Publikováno v:
Nucleic Acids Research
Bacterial transcription factors often function as DNA-binding proteins that selectively activate or repress promoters, although the biochemical mechanisms vary. In most well-understood examples, activators function by either increasing the affinity o