Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shamir R. Mehta"'
Autor:
Jack Hirsh, Stuart J. Connolly, Katy L. Simonsen, Sonia S. Anand, Guillaume Paré, Deepak L. Bhatt, Keith A.A. Fox, Salim Yusuf, Shamir R. Mehta, John W. Eikelboom
Publikováno v:
Paré, G, Mehta, S R, Yusuf, S, Anand, S S, Connolly, S J, Hirsh, J, Simonsen, K, Bhatt, D L, Fox, K A A & Eikelboom, J W 2010, ' Effects of CYP2C19 genotype on outcomes of clopidogrel treatment ', New England Journal of Medicine, vol. 363, no. 18, pp. 1704-14 . https://doi.org/10.1056/NEJMoa1008410
It has been suggested that clopidogrel may be less effective in reducing the rate of cardiovascular events among persons who are carriers of loss-of-function CYP2C19 alleles that are associated with reduced conversion of clopidogrel to its active met
Autor:
Shamir R, Mehta, Jean-Pierre, Bassand, Susan, Chrolavicius, Rafael, Diaz, John W, Eikelboom, Keith A A, Fox, Christopher B, Granger, Sanjit, Jolly, Campbell D, Joyner, Hans-Jurgen, Rupprecht, Petr, Widimsky, Rizwan, Afzal, Janice, Pogue, W C L, Wu
Publikováno v:
New England Journal of Medicine. 363:930-942
A b s t r ac t Background Clopidogrel and aspirin are widely used for patients with acute coronary syndromes and those undergoing percutaneous coronary intervention (PCI). However, evidencebased guidelines for dosing have not been established for eit
Autor:
Shamir R. Mehta
Publikováno v:
New England Journal of Medicine. 369:2263-2265
Primary percutaneous coronary intervention (PCI) has become the preferred method of reperfusion for patients with ST-segment elevation myocardial infarction (STEMI) when the procedure can be performed promptly by experts. Anticoagulation is important
Autor:
Warren J, Cantor, David, Fitchett, Bjug, Borgundvaag, John, Ducas, Michael, Heffernan, Eric A, Cohen, Laurie J, Morrison, Anatoly, Langer, Vladimir, Dzavik, Shamir R, Mehta, Charles, Lazzam, Brian, Schwartz, Amparo, Casanova, Shaun G, Goodman, J, Vincent
Publikováno v:
New England Journal of Medicine. 360:2705-2718
Background Patients with a myocardial infarction with ST-segment elevation who present to hospitals that do not have the capability of performing percutaneous coronary intervention (PCI) often cannot undergo timely primary PCI and therefore receive f
Autor:
Salim Yusuf, Gianni Tognoni, Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators, Susan Chrolavicius, Shamir R. Mehta, K K Fox, Zhao F
Publikováno v:
New England Journal of Medicine. 345:494-502
Background: Despite current treatments, patients who have acute coronary syndromes without ST-segment elevation have high rates of major vascular events. We evaluated the efficacy and safety of the antiplatelet agent clopidogrel when given with aspir