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Autor:
Vanessa Rouzier, Jean W. Pape
Publikováno v:
New England Journal of Medicine. 370:2067-2069
Despite evidence of the safety and efficacy of oral cholera vaccines, they were not included in the prevention package during the 2010 Haitian cholera epidemic. But some major obstacles to the use of OCVs in cholera outbreaks have since been overcome
Publikováno v:
New England Journal of Medicine. 370:195-197
Researchers have reported sequencing a fetal genome from cell-free fetal DNA in a pregnant woman's blood, heralding the possibility of performing whole-genome sequencing as early as the first trimester of pregnancy. This innovation raises ethical and
Autor:
James Olen Armitage
Publikováno v:
New England Journal of Medicine. 363:653-662
This article summarizes the issues involved in the treatment of patients with early-stage Hodgkin's lymphoma. Long-term follow-up reveals an increasing burden of complications in patients who received combined methods of treatment.
Autor:
M. Akhtar, Anthony Ogwu, Sajini Souda, E. Handelsman, Roger L. Shapiro, Joseph Makhema, Esther Tumbare, E. Moko, Loeto Mazhani, Claire Moffat, Myron Essex, Abstr Act, W. Snowden, Shahin Lockman, Sikhulile Moyo, U. Sharma, R. Tuomola, E. van Widenfelt, K. Mburu, Ibou Thior, Douglas Kitch, Kathleen M. Powis, S. Zwerski, Oluwemimo Jayeoba, Kenneth McIntosh, E. Lubega, Carolyn Wester, M. Martinez-Tristani, Jean Leidner, Aida Asmelash
Publikováno v:
New England Journal of Medicine. 362:2282-2294
The most effective highly active antiretroviral therapy (HAART) to prevent mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) in pregnancy and its efficacy during breast-feeding are unknown.We randomly assigned 560 HIV-1-infe
Autor:
Perri, Klass
Publikováno v:
New England Journal of Medicine. 362:1358-1361
Autor:
James M, Roberts, Leslie, Myatt, Catherine Y, Spong, Elizabeth A, Thom, John C, Hauth, Kenneth J, Leveno, Gail D, Pearson, Ronald J, Wapner, Michael W, Varner, John M, Thorp, Brian M, Mercer, Alan M, Peaceman, Susan M, Ramin, Marshall W, Carpenter, Philip, Samuels, Anthony, Sciscione, Margaret, Harper, Wendy J, Smith, George, Saade, Yoram, Sorokin, Garland B, Anderson, S, Tolivaisa
Publikováno v:
New England Journal of Medicine. 362:1282-1291
Oxidative stress has been proposed as a mechanism linking the poor placental perfusion characteristic of preeclampsia with the clinical manifestations of the disorder. We assessed the effects of antioxidant supplementation with vitamins C and E, init
Autor:
Michael W. Steffes, Kunihiro Matsushita, Elizabeth Selvin, Hong Zhu, Josef Coresh, Lynne E. Wagenknecht, Frederick L. Brancati, James S. Pankow
Publikováno v:
New England Journal of Medicine. 362:800-811
Fasting glucose is the standard measure used to diagnose diabetes in the United States. Recently, glycated hemoglobin was also recommended for this purpose.We compared the prognostic value of glycated hemoglobin and fasting glucose for identifying ad
Autor:
Christina R. Phares, Allen S. Craig, Melissa K. Van Dyke, Kathryn E. Arnold, Kathleen A. Shutt, Ruth Lynfield, Elizabeth R. Zell, Anne Schuchat, Janet C. Mohle-Boetani, Shelley M. Zansky, Ken Gershman, Lee H. Harrison, William Schaffner, Joseph Bareta, Craig Morin, Nancy L Spina, Susan Petit, Stephanie J. Schrag, Kathryn Wymore, Sandra N. Bulens, Ann Thomas
Publikováno v:
New England Journal of Medicine. 360:2626-2636
Group B streptococcal disease is one of the most common infections in the first week after birth. In 2002, national guidelines recommended universal late antenatal screening of pregnant women for colonization with group B streptococcus to identify ca
Autor:
Ashley Evans, Elizabeth Davis, William W. Andrews, Tina Simpson, Gretchen A. Cloud, Cynthia Flanigan, Meei Li Huang, Janie Hill, Changpin Zhang, Lawrence Corey, Robert F. Pass
Publikováno v:
New England Journal of Medicine. 360:1191-1199
Congenital infection with cytomegalovirus (CMV) is an important cause of hearing, cognitive, and motor impairments in newborns.In this phase 2, placebo-controlled, randomized, double-blind trial, we evaluated a vaccine consisting of recombinant CMV e
Autor:
K, Zaman, Eliza, Roy, Shams E, Arifeen, Mahbubur, Rahman, Rubhana, Raqib, Emily, Wilson, Saad B, Omer, Nigar S, Shahid, Robert F, Breiman, Robert E, Breiman, Mark C, Steinhoff
Publikováno v:
New England Journal of Medicine. 359:1555-1564
Background Young infants and pregnant women are at increased risk for serious consequences of influenza infection. Inactivated influenza vaccine is recommended for pregnant women but is not licensed for infants younger than 6 months of age. We assess