Zobrazeno 1 - 10
of 816
pro vyhledávání: ''
Autor:
Marco, Valgimigli, Enrico, Frigoli, Dik, Heg, Jan, Tijssen, Peter, Jüni, Pascal, Vranckx, Yukio, Ozaki, Marie-Claude, Morice, Bernard, Chevalier, Yoshinobu, Onuma, Stephan, Windecker, Pim A L, Tonino, Marco, Roffi, Maciej, Lesiak, Felix, Mahfoud, Jozef, Bartunek, David, Hildick-Smith, Antonio, Colombo, Goran, Stanković, Andrés, Iñiguez, Carl, Schultz, Ran, Kornowski, Paul J L, Ong, Mirvat, Alasnag, Alfredo E, Rodriguez, Aris, Moschovitis, Peep, Laanmets, Michael, Donahue, Sergio, Leonardi, Pieter C, Smits, Nguyen Ngoc, Quang
Publikováno v:
New England journal of medicine, 385(18), 1643-1655. Massachussetts Medical Society
The appropriate duration of dual antiplatelet therapy in patients at high risk for bleeding after the implantation of a drug-eluting coronary stent remains unclear.One month after they had undergone implantation of a biodegradable-polymer sirolimus-e
Autor:
Ned Lewis, Shaun J. Grannis, Stephanie A. Irving, Eduardo Azziz-Baumgartner, Rachael M. Porter, Sarah Ball, Eric P. Griggs, Yan Zhuang, Matthew E Levy, Kristin Dascomb, Edward Stenehjem, Suchitra Rao, Maria Demarco, Jennifer R. Verani, Pat Shifflett, Ousseny Zerbo, Kristin Goddard, Malini B. DeSilva, Natalie Olson, Stephanie J. Schrag, Manjusha Gaglani, Catherine H Bozio, J.A Arndorfer, Lenee Blanton, Bruce Fireman, Allison L. Naleway, Mark G. Thompson, Karthik Natarajan, Michelle A. Barron, Nimish R. Valvi, Elizabeth A Rowley, Toan C. Ong, Nicola P. Klein, Nancy Grisel, Sue Reynolds, William F. Fadel, Palak Patel, Alicia M Fry, Jill M. Ferdinands, Brian E. Dixon, Jungmi Han, Elyse O. Kharbanda, Rebecca J. Birch, Andrea Steffens
Publikováno v:
The New England Journal of Medicine
Background There are limited data on the effectiveness of the vaccines against symptomatic coronavirus disease 2019 (Covid-19) currently authorized in the United States with respect to hospitalization, admission to an intensive care unit (ICU), or am
Autor:
Gregory D. Huhn, Dipak R. Patel, Bharat Mocherla, Daniel Skovronsky, Kenneth L. Custer, Paul Klekotka, Imad Shawa, Andrew E. Schade, Janelle Sabo, Nicole L. Kallewaard, Michael Durante, Andrew C. Adams, Timothy R. Holzer, Ajay Nirula, Joseph Boscia, Masoud Azizad, Jose Cardona, Princy Kumar, Chad Crystal, Lei Shen, Peter Chen, Russell Perry, Corey Hebert, Richard E. Higgs, Robert L. Gottlieb, Matan C. Dabora, Philip J. Ebert, Jacob Van Naarden, Gerard J. Oakley, Jason Morris, Michael Dougan, Awawu Igbinadolor, Barry Heller
Publikováno v:
The New England Journal of Medicine
Background Patients with underlying medical conditions are at increased risk for severe coronavirus disease 2019 (Covid-19). Whereas vaccine-derived immunity develops over time, neutralizing monoclonal-antibody treatment provides immediate, passive i
Autor:
Rosemary Greenwood, Katie Breheny, Ian Thomas, Nichola Cooper, Quentin Hill, Kate Talks, Rachel Rayment, Catherine Bagot, Charlotte A Bradbury, Jenny Ingram, Gillian Evans, Rebecca Kandiyali, Julie Pell
Publikováno v:
Bradbury, C A, Ingram, J, Kandiyali, R, Breheny, K & Greenwood, R 2021, ' Mycophenolate Mofetil for First-Line Treatment of Immune Thrombocytopenia ', New England Journal of Medicine, vol. 385, no. 10, pp. 885-895 . https://doi.org/10.1056/NEJMoa2100596
BACKGROUND Immune thrombocytopenia (ITP) is a rare autoimmune thrombocytopenia with associated bleeding risk and fatigue. Recommended first line ITP treatment is with high dose glucocorticoids but side effects, heterogeneous responses and high relaps
Autor:
Rosa Pando, Nazarii Kobyliak, Milica Marjanovic Petkovic, Ángel Michael Ortiz Zúñiga, Kevser Onbasi, Hans Prozesky, Neslihan Bascil Tutuncu, Tomasz Skowerski, Kelley Branch, Vladimir Rafalskiy, Fernando Lanas, Dedrick Jordan, Felix Jebasingh, Türkan Paşalı Kilit, Hertzel Gerstein, Miljanka Vuksanovic, Aleksandar Djukic
Publikováno v:
New England Journal of Medicine. 385:896-907
Background: \ud Four glucagon-like peptide-1 (GLP-1) receptor agonists that are structurally similar to human GLP-1 have been shown to reduce the risk of adverse cardiovascular events among persons with type 2 diabetes. The effect of an exendin-based
Autor:
Joel M Trugman, Jessica Ailani, Lawrence Severt, Rosa Miceli, Michelle Finnegan, Peter J. Goadsby, Richard B Lipton, Hua Guo
Publikováno v:
New England Journal of Medicine. 385:695-706
Atogepant is an oral, small-molecule, calcitonin gene-related peptide receptor antagonist that is being investigated for the preventive treatment of migraine.In a phase 3, double-blind trial, we randomly assigned adults with 4 to 14 migraine days per
Autor:
Dankiewicz J., Cronberg T., Lilja G., Jakobsen J. C., Levin H., Ullen S., Rylander C., Wise M. P., Oddo M., Cariou A., Belohlavek J., Hovdenes J., Saxena M., Kirkegaard H., Young P. J., Pelosi P., Storm C., Taccone F. S., Joannidis M., Callaway C., Eastwood G. M., Morgan M. P. G., Nordberg P., Erlinge D., Nichol A. D., Chew M. S., Hollenberg J., Thomas M., Bewley J., Sweet K., Grejs A. M., Christensen S., Haenggi M., Levis A., Lundin A., During J., Schmidbauer S., Keeble T. R., Karamasis G. V., Schrag C., Faessler E., Smid O., Otahal M., Maggiorini M., Wendel Garcia P. D., Jaubert P., Cole J. M., Solar M., Borgquist O., Leithner C., Abed-Maillard S., Navarra L., Annborn M., Unden J., Brunetti I., Awad A., McGuigan P., Olsen R. B., Cassina T., Vignon P., Langeland H., Lange T., Friberg H., Nielsen N. Collaborators, Erik Roman Pognuz, Umberto Lucangelo, Giorgio Berlot, Elisabetta Macchini.
Publikováno v:
Dankiewicz, J, Cronberg, T, Lilja, G, Jakobsen, J C, Levin, H, Ullen, S, Rylander, C, Wise, M P, Oddo, M, Cariou, A, Belohlavek, J, Hovdenes, J, Saxena, M, Kirkegaard, H, Young, P J, Pelosi, P, Storm, C, Taccone, F S, Joannidis, M, Callaway, C, Eastwood, G M, Morgan, M P G, Nordberg, P, Erlinge, D, Nichol, A D, Chew, M S, Hollenberg, J, Thomas, M, Bewley, J, Sweet, K, Grejs, A M, Christensen, S, Haenggi, M, Levis, A, Lundin, A, During, J, Schmidbauer, S, Keeble, T R, Karamasis, G V, Schrag, C, Faessler, E, Smid, O, Otahal, M, Maggiorini, M, Wendel Garcia, P D, Jaubert, P, Cole, J M, Solar, M, Lange, T, Nielsen, N & TTM2 Trial Invest 2021, ' Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest ', New England Journal of Medicine, vol. 384, no. 24, pp. 2283-2294 . https://doi.org/10.1056/NEJMoa2100591
Lange, T & TTM2 Trial Investigators 2021, ' Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest ', The New England Journal of Medicine, vol. 384, no. 24, pp. 2283-2294 . https://doi.org/10.1056/NEJMoa2100591
Lange, T & TTM2 Trial Investigators 2021, ' Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest ', The New England Journal of Medicine, vol. 384, no. 24, pp. 2283-2294 . https://doi.org/10.1056/NEJMoa2100591
Hypothermia or Normothermia after Cardiac ArrestThis trial randomly assigned patients with coma after out-of-hospital cardiac arrest to undergo targeted hypothermia at 33 degrees C or normothermia with treatment of fever. At 6 months, there were no s
Autor:
Jerald, Sadoff, Glenda, Gray, An, Vandebosch, Vicky, Cárdenas, Georgi, Shukarev, Beatriz, Grinsztejn, Paul A, Goepfert, Carla, Truyers, Hein, Fennema, Bart, Spiessens, Kim, Offergeld, Gert, Scheper, Kimberly L, Taylor, Merlin L, Robb, John, Treanor, Dan H, Barouch, Jeffrey, Stoddard, Martin F, Ryser, Mary A, Marovich, Kathleen M, Neuzil, Lawrence, Corey, Nancy, Cauwenberghs, Tamzin, Tanner, Karin, Hardt, Javier, Ruiz-Guiñazú, Mathieu, Le Gars, Hanneke, Schuitemaker, Johan, Van Hoof, Frank, Struyf, Macaya, Douoguih, Marcus, Zervos
Publikováno v:
New England Journal of Medicine. 384:2187-2201
The Ad26.COV2.S vaccine is a recombinant, replication-incompetent human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in a prefusion-stabilized conformation.In an internation
Autor:
Shabir A, Madhi, Vicky, Baillie, Clare L, Cutland, Merryn, Voysey, Anthonet L, Koen, Lee, Fairlie, Sherman D, Padayachee, Keertan, Dheda, Shaun L, Barnabas, Qasim E, Bhorat, Carmen, Briner, Gaurav, Kwatra, Khatija, Ahmed, Parvinder, Aley, Sutika, Bhikha, Jinal N, Bhiman, As'ad E, Bhorat, Jeanine, du Plessis, Aliasgar, Esmail, Marisa, Groenewald, Elizea, Horne, Shi-Hsia, Hwa, Aylin, Jose, Teresa, Lambe, Matt, Laubscher, Mookho, Malahleha, Masebole, Masenya, Mduduzi, Masilela, Shakeel, McKenzie, Kgaogelo, Molapo, Andrew, Moultrie, Suzette, Oelofse, Faeezah, Patel, Sureshnee, Pillay, Sarah, Rhead, Hylton, Rodel, Lindie, Rossouw, Carol, Taoushanis, Houriiyah, Tegally, Asha, Thombrayil, Samuel, van Eck, Constantinos K, Wibmer, Nicholas M, Durham, Elizabeth J, Kelly, Tonya L, Villafana, Sarah, Gilbert, Andrew J, Pollard, Tulio, de Oliveira, Penny L, Moore, Alex, Sigal, Alane, Izu, Peter, Zuidewind
Publikováno v:
The New England Journal of Medicine : NEJM / Publ. by the Massachusetts Medical Society
Background Assessment of the safety and efficacy of vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in different populations is essential, as is investigation of the efficacy of the vaccines against emerging SARS-CoV
Autor:
Rijn, R. van, Schurink, I.J., Vries, Y. de, Berg, A.P. van den, Cerisuelo, M.C., Murad, S.D., Erdmann, J.I., Gilbo, N., Haas, R.J. de, Heaton, N., Hoek, B. van, Huurman, V.A.L., Jochmans, I., Leeuwen, O.B. van, Meijer, V.E. de, Monbaliu, D., Polak, W.G., Slangen, J.J.G., Troisi, R.I., Vanlander, A., Jonge, J. de, Porte, R.J., DHOPE DCD Trial Investigators
Publikováno v:
New England Journal of Medicine, 384(15), 1391-1401. MASSACHUSETTS MEDICAL SOC
New England Journal of Medicine, 384(15), 1391-1401. Massachussetts Medical Society
New England Journal of Medicine, 384(15), 1391-1401. Massachussetts Medical Society
BACKGROUND: Transplantation of livers obtained from donors after circulatory death is associated with an increased risk of nonanastomotic biliary strictures. Hypothermic oxygenated machine perfusion of livers may reduce the incidence of biliary compl