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Autor:
Fernando D. Martinez
Publikováno v:
New England Journal of Medicine. 375:871-878
The conventional thinking about COPD is that exposures in adult life, such as smoking, lead to a low FEV1:FVC ratio, the physiological hallmark of COPD. In this review, the effect of early-life exposures on the lung that could lead to expiratory airf
Autor:
Paul Saenger
Publikováno v:
New England Journal of Medicine. 335:1749-1754
Publikováno v:
New England Journal of Medicine. 324:1710-1715
Management of abnormal genital bleeding in girls, adolescents and women, in pregnancy, and in postmenopausal women is reviewed under the headings of evaluation and treatment. In childhood all genital bleeding is clinically significant: it is due to a
Publikováno v:
New England Journal of Medicine. 292:278-281
Since it is still uncertain whether moderate degrees of alpha1-antitrypsin deficiency predispose to the development of lung disease, data obtained from a stratified random sample of white households in Tucson, Arizona, consisting of 2586 subjects ove
Autor:
Harold C. Stuart
Publikováno v:
New England Journal of Medicine. 236:507-513
Protein During Infancy and Childhood Requirements The primary function of protein in the diet is to provide the amino acids that are essential for the synthesis of tissue proteins characteristic of...
Autor:
Allan L. Drash
Publikováno v:
New England Journal of Medicine. 300:1211-1213
It has long been known that insulin-deficiency diabetes mellitus (IDDM) results from an inflammatory process of the islet tissue of the pancreas (insulitis), leading to essentially complete destruc...
Autor:
George F. Cahill
Publikováno v:
New England Journal of Medicine. 299:412-413
Central in the constellation of anatomic and physiologic abnormalities that make up the syndrome of diabetes mellitus in man is an absolute or relative deficiency in pancreatic beta-cell function. ...
Autor:
Castronovo Fp
Publikováno v:
New England Journal of Medicine. 315:1679-1680
Autor:
Brian E. Henderson, George Linden
Publikováno v:
New England Journal of Medicine. 286:760-761
In a review of the California Tumor Registry from 1950-1969, which records 1/3 of all cancer cases in California, there was an increase in the number of cancers of the vagina, corpus uteri, prostate, testis, and bladder (male) for the 10-19 year old