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Autor:
Jadambaa Tsolmo, Jutmaan Yanjmaa, Murneren Tunsag, Davaasambuu Ganmaa, Saranjav Ariunzaya, Polyna Khudyakov, Tserenkhuu Enkhtsetseg, Erdenebaatar Sumiya, Dorjnamjil Khulan, Garmaa Gantsetseg, Buyanjargal Uyanga, Ben J. Marais, Ankhbat Munkhzaya, Davaasambuu Enkhmaa, Donna Spiegelman, Baigali Delgerekh, Batbileg Bolortuya, James A Seddon, Ochirbat Batbayar, Bazarsaikhan Amarsaikhan, Adrian R. Martineau, Ganbaatar Erdenetuya, Xin Zhou
Publikováno v:
N Engl J Med
BACKGROUND: Vitamin D metabolites support innate immune responses to Mycobacterium tuberculosis. Data from phase 3, randomized, controlled trials of vitamin D supplementation to prevent tuberculosis infection are lacking. METHODS: We randomly assigne
Autor:
Angela, Schulz, Temitayo, Ajayi, Nicola, Specchio, Emily, de Los Reyes, Paul, Gissen, Douglas, Ballon, Jonathan P, Dyke, Heather, Cahan, Peter, Slasor, David, Jacoby, Alfried, Kohlschütter, Barbara, Csányi
Publikováno v:
New England Journal of Medicine. 378:1898-1907
Recombinant human tripeptidyl peptidase 1 (cerliponase alfa) is an enzyme-replacement therapy that has been developed to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease, a rare lysosomal disorder that causes progressive dementia in childre
Autor:
Bruce, Aylward, Philippe, Barboza, Luke, Bawo, Eric, Bertherat, Pepe, Bilivogui, Isobel, Blake, Rick, Brennan, Sylvie, Briand, Jethro Magwati, Chakauya, Kennedy, Chitala, Roland M, Conteh, Anne, Cori, Alice, Croisier, Jean-Marie, Dangou, Boubacar, Diallo, Christl A, Donnelly, Christopher, Dye, Tim, Eckmanns, Neil M, Ferguson, Pierre, Formenty, Caroline, Fuhrer, Keiji, Fukuda, Tini, Garske, Alex, Gasasira, Stephen, Gbanyan, Peter, Graaff, Emmanuel, Heleze, Amara, Jambai, Thibaut, Jombart, Francis, Kasolo, Albert Mbule, Kadiobo, Sakoba, Keita, Daniel, Kertesz, Moussa, Koné, Chris, Lane, Jered, Markoff, Moses, Massaquoi, Harriet, Mills, John Mike, Mulba, Emmanuel, Musa, Joel, Myhre, Abdusalam, Nasidi, Eric, Nilles, Pierre, Nouvellet, Deo, Nshimirimana, Isabelle, Nuttall, Tolbert, Nyenswah, Olushayo, Olu, Scott, Pendergast, William, Perea, Jonathan, Polonsky, Steven, Riley, Olivier, Ronveaux, Keita, Sakoba, Ravi, Santhana Gopala Krishnan, Mikiko, Senga, Faisal, Shuaib, Maria D, Van Kerkhove, Rui, Vaz, Niluka, Wijekoon Kannangarage, Zabulon, Yoti
Publikováno v:
Europe PubMed Central
New England Journal of Medicine
New England Journal of Medicine
BACKGROUND\ud \ud On March 23, 2014, the World Health Organization (WHO) was notified of an outbreak of Ebola virus disease (EVD) in Guinea. On August 8, the WHO declared the epidemic to be a "public health emergency of international concern."\ud \ud
Autor:
Christina Frank, Maria Wadl, Jakob P. Cramer, Matthias an der Heiden, Markus J Kemper, Dirk Werber, Rita Prager, Gérard Krause, Lisa A King, Bettina Rosner, Luise Müller, Udo Buchholz, Sabine Jordan, Alexander Zoufaly, Helen Bernard, Hus investigation team, Mona Askar, Anke Spode, Per Follin, Mirko Faber, Klaus Stark, Angelika Fruth
Publikováno v:
New England Journal of Medicine. 365:1771-1780
Background We describe an outbreak of gastroenteritis and the hemolytic–uremic syndrome caused by Shiga-toxin–producing Escherichia coli in Germany in May, June, and July, 2011. The consumption of sprouts was identified as the most likely vehicle
Autor:
Blümcke, I., Spreafico, R., Haaker, G., Coras, R., Kobow, K., Bien, C.G., Pfäfflin, M., Elger, C., Widman, G., Schramm, J., Becker, A., Braun, K.P.J., Leijten, F.S.S., Baayen, J.C., Aronica, E., Chassoux, F., Hamer, H., Stefan, H., Rössler, K., Thom, M., Walker, M.C., Sisodiya, S.M., Duncan, J.S., McEvoy, A.W., Pieper, T., Holthausen, H., Kudernatsch, M., Meencke, H.J., Kahane, P., Schulze-Bonhage, A., Zentner, J., Heiland, D., Urbach, H., Steinhoff, B.J., Bast, T., Tassi, L., Lo Russo, G., Ozkara, C., Oz, B., Krsek, P., Vogelgesang, S., Runge, U., Lerche, H., Weber, Y., Honavar, M., Pimentel, J., Arzimanoglou, A., Ulate-Campos, A., Noachtar, S., Hartl, E., Schijns, O.E.M.G., Guerrini, R., Barba, C., Jacques, T.S., Cross, J.H., Feucht, M., Mühlebner, A., Grunwald, T., Trinka, E., Winkler, P.A., Gil-Nagel, A., Toledano Delgado, R., Mayer, T., Lutz, M., Zountsas, B., Garganis, K., Rosenow, F., Hermsen, A., Örtzen, T.J. von, Diepgen, T.L., Avanzini, G., Aparicio, J., Bento, C., Beckervordersandforth, J., Buccoliero, A.M., Cabral, P., Chamadoira, C., Colon, A.J., Chabardès, S., Carpenter, S., Czech, T., Dressler, A., Deleo, F., Dílio, A., Dings, J., Devaux, B., De Tisi, J., De Bellescize, J., Ebner, A., Franke, K., Groeppel, G., Giordano, F., Gozzo, F., Garbelli, R., Guenot, M., García‐Morales, I., Gómez‐Angulo, J.C., Garcia, G., Hainfellner, J.A., Höfler, J., Hoogland, G., Hendriks, M.P.H., Hofman, P., Harding, B., Huppertz, H.J., Herms, J., Hilkman, D.M.W., Hamelin, S., Idema, S., Jansen, F.E., Jahodova, A., Keeley, A., Kalss, G., Kudr, M., Kroell, J., Kokkinos, V., Keo Kosal, P., Kalbhenn, T., Leitinger, M., Landré, E., Melo Pires, M., Matas, A., Mann, M.W., Ostrowsky‐Coste, K., Prinz, M., Puttinger, G., Peraud, A., Rangel Pinho, R., Romero, C., Rego, R., Rouhl, R.P.W., Ryvlin, P., Rumia, J., Rampp, S., Scholl, T., Schulz, R., Stone, T.J., Streichenberger, N., Tisdall, M., Turak, B., Taipa, R., Uzan, M., Kranen‐Mastenbroek, V. van, Varlet, P., Vlooswijk, M.C.G., Wagner, L., Weis, S.
Publikováno v:
New England Journal of Medicine, 377(17), 1648-1656. Massachussetts Medical Society
The New England Journal of Medicine, 377, 1648-1656
Blumcke, I, Spreafico, R, Haaker, G, Coras, R, Kobow, K, Bien, C G, Pfäfflin, M, Elger, C, Widman, G, Schramm, J, Becker, A, Braun, K P, Leijten, F, Baayen, J C, Aronica, E, Chassoux, F, Hamer, H, Stefan, H, Rössler, K, Thom, M, Walker, M C, Sisodiya, S M, Duncan, J S, McEvoy, A W, Pieper, T, Holthausen, H, Kudernatsch, M, Meencke, H J, Kahane, P, Schulze-Bonhage, A, Zentner, J, Heiland, D H, Urbach, H, Steinhoff, B J, Bast, T, Tassi, L, Lo Russo, G, Özkara, C, Oz, B, Krsek, P, Vogelgesang, S, Runge, U, Lerche, H, Weber, Y, Honavar, M, Pimentel, J, Arzimanoglou, A, Ulate-Campos, A, Noachtar, S, Hartl, E & EEBB Consortium 2017, ' Histopathological findings in brain tissue obtained during epilepsy surgery ', New England Journal of Medicine, vol. 377, no. 17, pp. 1648-1656 . https://doi.org/10.1056/NEJMoa1703784
New England Journal of Medicine, 377(17), 1648-1656. MASSACHUSETTS MEDICAL SOCIETY
The New England Journal of Medicine, 377, 17, pp. 1648-1656
New England Journal of Medicine, 377(17), 1648. Massachussetts Medical Society
New England journal of medicine, 377(17), 1648-1656. Massachussetts Medical Society
The New England Journal of Medicine, 377, 1648-1656
Blumcke, I, Spreafico, R, Haaker, G, Coras, R, Kobow, K, Bien, C G, Pfäfflin, M, Elger, C, Widman, G, Schramm, J, Becker, A, Braun, K P, Leijten, F, Baayen, J C, Aronica, E, Chassoux, F, Hamer, H, Stefan, H, Rössler, K, Thom, M, Walker, M C, Sisodiya, S M, Duncan, J S, McEvoy, A W, Pieper, T, Holthausen, H, Kudernatsch, M, Meencke, H J, Kahane, P, Schulze-Bonhage, A, Zentner, J, Heiland, D H, Urbach, H, Steinhoff, B J, Bast, T, Tassi, L, Lo Russo, G, Özkara, C, Oz, B, Krsek, P, Vogelgesang, S, Runge, U, Lerche, H, Weber, Y, Honavar, M, Pimentel, J, Arzimanoglou, A, Ulate-Campos, A, Noachtar, S, Hartl, E & EEBB Consortium 2017, ' Histopathological findings in brain tissue obtained during epilepsy surgery ', New England Journal of Medicine, vol. 377, no. 17, pp. 1648-1656 . https://doi.org/10.1056/NEJMoa1703784
New England Journal of Medicine, 377(17), 1648-1656. MASSACHUSETTS MEDICAL SOCIETY
The New England Journal of Medicine, 377, 17, pp. 1648-1656
New England Journal of Medicine, 377(17), 1648. Massachussetts Medical Society
New England journal of medicine, 377(17), 1648-1656. Massachussetts Medical Society
Item does not contain fulltext Background: Detailed neuropathological information on the structural brain lesions underlying seizures is valuable for understanding drug-resistant focal epilepsy. Methods: We report the diagnoses made on the basis of r
Autor:
Celia Alpuche-Aranda, Mauricio Hernandez, Mark A. Miller, Hugo López-Gatell, Gerardo Chowell, M Arantxa Colchero, Stefano M. Bertozzi
Publikováno v:
New England Journal of Medicine. 361:674-679
Background In the spring of 2009, an outbreak of severe pneumonia was reported in conjunction with the concurrent isolation of a novel swine-origin influenza A (H1N1) virus (S-OIV), widely known as swine flu, in Mexico. Influenza A (H1N1) subtype vir
Autor:
Ross McManus, Neil Walker, Patrick Dubois, Cisca Wijmenga, Kate Downes, Graham A. Heap, Joanna M. M. Howson, David A. van Heel, Karen A. Hunt, Jason D. Cooper, Vincent Plagnol, John A. Todd, David Clayton, Jennie H M Yang, Helen Stevens, Deborah J. Smyth
Publikováno v:
New England Journal of Medicine, 359(26), 2767-2777. MASSACHUSETTS MEDICAL SOC
Two inflammatory disorders, type 1 diabetes and celiac disease, cosegregate in populations, suggesting a common genetic origin. Since both diseases are associated with the HLA class II genes on chromosome 6p21, we tested whether non-HLA loci are shar
Autor:
Annie Reynolds, Joanne Berghout, Irena Kirillova, John B. Wallingford, Pierre Drapeau, Jonathan R. McDearmid, Zoha Kibar, Elena Torban, Melissa Mathieu, Patrizia De Marco, Julie M. Hayes, Elisa Merello, Philippe Gros, Valeria Capra
Publikováno v:
New England Journal of Medicine. 356:1432-1437
Neural-tube defects such as anencephaly and spina bifida constitute a group of common congenital malformations caused by complex genetic and environmental factors. We have identified three mutations in the VANGL1 gene in patients with familial types
Publikováno v:
New England Journal of Medicine. 343:1430-1438
The influence of the patterns of onset of multiple sclerosis and relapses of the disease on the time course of irreversible disability is controversial.In 1844 patients with multiple sclerosis who were followed for a mean (+/- SD) of 11 +/- 10 years,
Autor:
Stephanie J. Schrag, Lewis B. Lefkowitz, Arthur Reingold, Lee H. Harrison, James L. Hadler, Paul R. Cieslak, Monica M. Farley, Anne Schuchat, Richard Danila, Sara Zywicki
Publikováno v:
New England Journal of Medicine. 342:15-20
Background Group B streptococcal infections are a leading cause of neonatal mortality, and they also affect pregnant women and the elderly. Many cases of the disease in newborns can be prevented by the administration of prophylactic intrapartum antib