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Autor:
Rolf M. Zinkernagel
Publikováno v:
New England Journal of Medicine. 345:1331-1335
With this article by Nobel laureate Rolf Zinkernagel, the Immunology series that began in July 2000 comes to an end. Zinkernagel's thesis concerns the influence of a mother's immunologic memory on the effectiveness of childhood vaccination and the su
Publikováno v:
New England Journal of Medicine. 310:1561-1566
A long-term follow-up of approximately 50,000 children who received the Hemophilus influenzae type b capsular polysaccharide vaccine in 1974 at three months to five years of age has shown good protective efficacy in those who received the vaccine at
Publikováno v:
New England Journal of Medicine. 270:870-874
THE effectiveness of artificial immunization in preventing influenza has been difficult to evaluate. A reduction in the incidence of disease occurs when inactivated vaccines containing the antigen of the prevalent type of influenza are applied before
Publikováno v:
New England Journal of Medicine. 278:227-232
Jeryl-Lynn strain (B level) live, attenuated mumps-virus vaccine was administered to 6283 initially susceptible children and 163 adults, including 132 males. There was no evident clinical reaction to the vaccine either in adults or in children includ
Publikováno v:
New England Journal of Medicine. 273:198-201
LIVE measles vaccine1 given without gamma globulin protects children from the clinical manifestations of natural measles even if given as late as three days after exposure.2 3 4 Krugman et al.5 have suggested that this early protective effect may be
Autor:
Rizalina Llanes-Rodas, Chien Liu
Publikováno v:
New England Journal of Medicine. 275:516-523
SEVERAL acute systemic viral illnesses have been associated with the presence of multinucleated giant cells or inclusion-bearing cells (or both) detected in nasal discharges1 and specimens of urine in human patients.2 3 4 5 6 7 Such cells have also b
Autor:
Pearay L. Ogra
Publikováno v:
New England Journal of Medicine. 284:59-64
Poliovirus antibody levels in nasopharynx and serum were studied before and after tonsillectomy and adenoidectomy in 40 children previously immunized with live poliovaccine. Before operation, γA poliovirus antibody was present in the nasopharynx of
Publikováno v:
New England Journal of Medicine. 289:1357-1359
Autor:
Stephen C. Schoenbaum
Publikováno v:
New England Journal of Medicine. 298:621-622
Inactivated influenza vaccine is the most widely used vaccine in the United States, with annual sales of approximately 15 to 20 million doses. It is also one of the least satisfactory immunizing ag...