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Publikováno v:
Neurotoxicology and Teratology. 73:49-53
Objective In this study, we aimed to compare the analgesic and toxic effects of Venenum Bufonis (VB) with those of cinobufagin (CBG), a monomer isolated from VB, to provide the experimental basis for further research and development of VB. Methods Af
Publikováno v:
Neurotoxicology and Teratology. 73:67-75
Organophosphates insecticides (OPs) are common surface water contaminants in both urban and agricultural landscapes. Neurobehavioral effects on larval fish are known to occur at concentrations higher than those reported in the environment. The aim of
Autor:
Courtney Stanley, Kimberly S. Grant, Nina Isoherranen, Brenda Crouthamel, Rebekah Petroff, Sara Shum, Jing Jing, Noelle McKain, Thomas M. Burbacher
Publikováno v:
Neurotoxicology and Teratology. 72:10-21
Domoic Acid (DA) is a naturally-occurring excitotoxin, produced by marine algae, which can bioaccumulate in shellfish and finfish. The consumption of seafood contaminated with DA is associated with gastrointestinal illness that, in the case of high D
Publikováno v:
Neurotoxicology and Teratology. 71:32-40
Exposure to organophosphate (OP) compounds leads to behavioral alterations. To determine whether paraoxon has effects on anxiety, anxiety-like behaviors were assessed in paraoxon-exposed rats. Protein expression of glutamate transporters has also bee
Publikováno v:
Neurotoxicology and teratology. 87
Gestational exposure to methylmercury disrupts dopamine-mediated behavior and produces heightened sensitivity to monoamine agonists later in life. This has been reported and replicated following both pre- and post-natal exposure. Impacts of methylmer
Autor:
Nigel Paneth, Kurunthachalam Kannan, Nicole M. Talge, Alicynne N. Glazier-Essalmi, Courtney C. Carignan, Rajendiran Karthikraj, Rita S Strakovsky, Brooke Ingersoll, Douglas M. Ruden, Diana K Haggerty
Publikováno v:
Neurotoxicol Teratol
Background Prenatal exposure to environmental chemicals has been associated with Autism Spectrum Disorder (ASD) symptoms in some, but not all, studies, but most research has not accounted for other childhood behavior problems. Objectives To evaluate
Publikováno v:
Neurotoxicology and teratology. 84
Phosalone (Pln) is an organophosphorus pesticide acetylcholinesterase (AChE) inhibitor. Blockade of AChE amplifies ACh signaling that is related to depressive symptoms. The effects of Pln exposure were evaluated on depressive behavior in mice and the
Autor:
Mehmet Erman Erdemli, Eyup Altinoz, Harika Gozukara Bag, Sezin Demirtas, Birgul Yigitcan, Yusuf Turkoz, M. Arif Aladag
Publikováno v:
Neurotoxicology and Teratology. 67:37-43
Objectives The aim of this study is to elucidate the possible mechanism of neurotoxic effect of acrylamide (AA) applied during pregnancy on fetal brain development and to show the effect of N-acetylcysteine (NAC) on AA toxicity. Materials and methods
Publikováno v:
Neurotoxicology and Teratology. 66:132-138
Background Folates in their role as key one carbon donors, are essential for two major pathways: the synthesis of DNA and RNA precursors and DNA methylation. A growing body of evidence from epidemiological studies indicates a possible association bet
Autor:
Tomomi Workman, William C. Griffith, Toby B. Cole, Julie Ju Young Park, Sungwoo Hong, Elaine M. Faustman, Lucio G. Costa, Motohiro Shiotani, Thomas M. Burbacher
Publikováno v:
Neurotoxicology and Teratology. 64:8-19
Domoic acid (DA) is an algal toxin which has been associated with significant neurotoxicity in humans, non-human primates, rodents, and marine mammals. Developmental exposure to DA is believed to result in neurotoxicity that may persist into adulthoo