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Publikováno v:
Neurotoxicology and Teratology. 71:32-40
Exposure to organophosphate (OP) compounds leads to behavioral alterations. To determine whether paraoxon has effects on anxiety, anxiety-like behaviors were assessed in paraoxon-exposed rats. Protein expression of glutamate transporters has also bee
Publikováno v:
Neurotoxicology and Teratology. 61:7-16
Toluene is the main component of a variety of inhalants that are used for intoxication purposes. Alterations in memory have been reported in inhalant users; however, it is unclear whether these impairments could be reversed, and the mechanisms involv
Autor:
Frances M. D. Gulland, Colleen Reichmuth, Sophie Dennison, Andrew Rouse, Bill Van Bonn, Peter F. Cook
Publikováno v:
Neurotoxicology and Teratology. 57:95-105
Domoic acid is a naturally occurring algal toxin that causes neurological symptoms and mortality in exposed marine life. California sea lions (Zalophus californianus) are the most visible victims, and suffer epilepsy and progressive hippocampal atrop
Autor:
Beverly A. Huang, Robert J. DeLorenzo, Laxmikant S. Deshpande, Kristin F. Phillips, Robert E. Blair
Publikováno v:
Neurotoxicology and Teratology. 56:81-86
Organophosphate (OP) compounds which include nerve agents and pesticides are considered chemical threat agents. Currently approved antidotes are crucial in limiting OP mediated acute mortality. However, survivors of lethal OP exposure exhibit delayed
Autor:
Ana Cláudia Monteiro Braga, Ana Flávia Furian, Félix Alexandre Antunes Soares, A.B. Poersch, Michele Rechia Fighera, Luiz Fernando Freire Royes, F. Trombetta, Leandro Rodrigo Ribeiro, Camilla de Oliveira Lima, Fernando Dobrachinski, Mauro Schneider Oliveira, Naieli Schiefelbein Souto
Publikováno v:
Neurotoxicology and Teratology. 51:61-67
Fumonisin B1 (FB1) is a Fusarium spp. mycotoxin which constitutes a major public health issue because of its worldwide distribution and diversity of toxic effects.While the liver and kidney are considered the major target organs of FB1 toxicity in se
Autor:
Rahime Sekerci, Narin Derin, Eren Ogut, Mutay Aslan, Fatos Belgin Yildirim, Güven Akçay, Leyla Sati
Publikováno v:
Neurotoxicology and Teratology. 76:106839
Recent developments in the field of insecticide exposure have led to a renewed interest in alternative antioxidant therapy. The present study was to investigate the neuroprotective role of syringic acid (SA, 25 mg/kg/day) on the neurotoxicity and oxi
Autor:
Linda L. Chao, Yu Zhang
Publikováno v:
Neurotoxicology and teratology. 68
In early March 1991, shortly after the end of the Gulf War (GW), a munitions dump was destroyed at Khamisiyah, Iraq. Later, in 1996, the dump was found to have contained the organophosphorus (OP) nerve agents sarin and cyclosarin. We previously repor
Publikováno v:
Neurotoxicology and Teratology. 40:17-27
Polybrominated diphenyl ethers (PBDEs) are a group of chemicals widely used as flame retardants; the lower brominated forms (1–5 bromine atoms) are highly neurotoxic and are presently not in commercial use. The highest brominated, the decabromodiph
Publikováno v:
Neurotoxicology and Teratology. 33:297-302
In the present work, in vivo ROS formation and the activity of antioxidant enzymes in the hippocampus and the cerebellum of sodium metavanadate (NaVO₃) treated rats were studied. Rats were i.p. injected with 3 mg/kg bw/day (V₁ group) or with 7.2
Publikováno v:
Neurotoxicology and Teratology. 28:354-362
The phytoplankton-derived neurotoxin, domoic acid (DOM), frequently causes poisoning of marine animals and poses an increasing threat to public health through contamination of seafood. In this study, we used stereotactic microinjection technique to a