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Autor:
Sonja Suntrup-Krueger, Tobias Ruck, Stefan Bittner, Sven G. Meuth, Tobias Warnecke, Paul Muhle, Inga Claus, Rainer Dziewas, Thomas Marian, Jens Burchard Schröder, Jens Minnerup
Publikováno v:
Neurosignals, Vol 25, Iss 1, Pp 74-87 (2017)
Background/Aims: Substance P (SP) is a neuropeptide, likely acting as a neurotransmitter in the pharyngeal mucosa enhancing the swallow and cough reflex. Pharyngeal Electrical Stimulation (PES) induces a temporary increase of salivary SP levels in he
Autor:
Verónica Pérez de la Cruz, Irma Gabriela González-Herrera, Abel Santamaría, Isaac Túnez, José Pedraza-Chaverri, Paul Carrillo-Mora, Inmaculada Tasset, Armando Luna-López, Mina Königsberg, Perla D. Maldonado, Syed F. Ali, Diana Elinos-Calderón
Publikováno v:
Neurosignals. 18:24-31
Tert-butylhydroquinone (tBHQ) is a xenobiotic with reported antioxidant properties. tBHQ has been shown to induce nuclear translocation of the transcription factor NF-E2-related factor 2 (Nrf2) to further activate the antioxidant response element (AR
Autor:
Qing Ping Yu, Xi Nan Yi, Rui Wang, Gui Xiang Zhang, Linfeng Zheng, Han Wang, Jian Wei Zhang, Qi Ben Wang, Yuanzhong Xu
Publikováno v:
Neurosignals. 18:49-56
Hepatocyte growth factor (HGF) and its receptor c-Met play pivotal roles in post-traumatic regeneration of the nervous system. However, following peripheral nerve injury, the role and regulation of the HGF/c-Met system is less clear. Therefore, using
Publikováno v:
Neurosignals, 13(5), 207-226
The awareness in specific brain centers of angina pectoris most often results from ischemic episodes in the heart. These ischemic episodes induce the release of a collage of chemicals that activate chemosensitive and mechanoreceptive receptors in the
Publikováno v:
Neurosignals. 12:71-77
Experimental evidence has been presented connecting melatonin with the prevention or treatment of gastrointestinal disorders either by the scavenging properties of active oxygen or by receptor-mediated stimulation of gene expression of neutralizing e
Publikováno v:
Neurosignals. 11:151-157
By using immunohistochemical staining for FOS protein in the spinal cord, the role of capsaicin receptors on the sciatic nerve was investigated. After topical application of capsaicin (1%) to the sciatic nerve, FOS-like immunoreactive (FOS-LI) neuron
Autor:
Marek Pawlikowski, Michal Karasek
Publikováno v:
Neurosignals. 8:75-78
The antiproliferative effects of melatonin and CGP 52608, an exogenous ligand for RZR/ROR receptors, are compared in the present paper. Both compounds exerted similar inhibitory effects on the proliferation of neoplastic cells in mouse colonic adenoc
Publikováno v:
Neurosignals. 8:256-260
We have developed an animal model of hypoxic preconditioning and assumed that oxygen radicals and their endogenous scavenging enzymes may play an important role in the preconditioning. To test this hypothesis, activities of superoxide dismutase (SOD)
Publikováno v:
Neurosignals. 7:45-54
A bidirectional flow of informations exists between the central nervous system and the immune system. Cytokines play a crucial role in this communication and exert several neuromodulatory actions. This short review considers some data concerning the
Autor:
Akira Warashina
Publikováno v:
Neurosignals. 7:307-320
Modulatory effects of the activation of either protein kinase C (PKC) by phorbol 12,13-dibutyrate (PDBu) or protein kinase A (PKA) by forskolin on stimulant-evoked secretory processes in the perfused rat adrenal medulla were studied. PDBu or forskoli