Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michael, Gill"'
Autor:
Kevin J. Mitchell, Stephen Shovlin, Michael Gill, Albert Sanfeliu, Aiden Corvin, Donna McAllister, Niall Mortimer, Stefania Bellini, Ines Molinos, Daniela Tropea
Publikováno v:
Neuroscience Letters. 621:111-116
Methyl-CpG binding protein 2 (MECP2) is a chromosome-binding protein that regulates the development and maintenance of brain circuits. Altered function of the protein product of MECP2 plays an important role in the etiology of many neurodevelopmental
Autor:
Graham E. Little, Michael Gill, Ines Molinos, Derek W. Morris, Gary Donohoe, Daniela Tropea, Aiden Corvin
Publikováno v:
Neuroscience Letters. 520:51-56
Insulin-like growth factor-1 (IGF1) and its active peptide (1-3)IGF1 modulate brain growth and plasticity and are candidate molecules for treatment of brain disorders. IGF1 N-terminal portion is naturally cleaved to generate the tri-peptide (1-3)IGF1
Autor:
William P. Gilks, Michael Gill, Derek W. Morris, Aiden Corvin, Elizabeth Cummings, Emma H. Allott, Gary Donohoe
Publikováno v:
Neuroscience Letters. 468:229-233
Schizophrenia is a heritable mental disorder with a complex genetic aetiology potentially implicating glutamatergic dysfunction. Following a search for functionally relevant genes with evidence of linkage to schizophrenia, we selected HOMER2 for as a
Autor:
Niamh Kenny, Gary Donohoe, Siobhan Schwaiger, Kevin A. McGhee, Michael Gill, Derek W. Morris, Kevin Murphy, Aiden Corvin, Jeanne Marie Nangle
Publikováno v:
Neuroscience Letters. 426:97-100
A series of genetic studies have identified the D-amino acid oxidase (DAO) gene as potentially contributing to schizophrenia susceptibility. An interacting gene, D-amino acid oxidase activator (DAOA) has also been implicated and it has been suggested
Autor:
Colm McDonald, John L. Waddington, Aiden Corvin, Timothy G. Dinan, April Hargreaves, Michael Gill, Gary Donohoe, Ciara Fahey, Francis A. O'Neill, Susan Moore, Kieran C. Murphy, Elizabeth Cummings, Derek W. Morris, E. O'Callaghan
Publikováno v:
Cummings, E, Donohoe, G, Hargreaves, A, Moore, S, Fahey, C, Dinan, T G, McDonald, C, O'Callaghan, E, O'Neill, F A, Waddington, J L, Murphy, K C, Morris, D W, Gill, M & Corvin, A 2013, ' Mood congruent psychotic symptoms and specific cognitive deficits in carriers of the novel schizophrenia risk variant at MIR-137 ', Neuroscience Letters, vol. 532, no. 1, pp. 33-38 . https://doi.org/10.1016/j.neulet.2012.08.065
Objective The Schizophrenia Psychiatric Genome-wide Association (GWAS) Consortium recently reported on five novel schizophrenia susceptibility loci. The most significant finding mapped to a micro-RNA, MIR-137, which may be involved in regulating the
Autor:
Matthew Hill, David Skuse, Richard Anney, Michael Gill, Lindsey Kent, Katherine E. Tansey, Astrid M. Vicente, Louise Gallagher, Lynne E Cochrane, Catarina Correia, Keeley J. Brookes
Publikováno v:
Neuroscience letters. 474(3)
Oxytocin (OXT) has been hypothesized to play a role in aetiology of autism based on a demonstrated involvement in the regulation of social behaviours. It is postulated that OXT reduces activation of the amygdala, inhibiting social anxiety, indicating
Autor:
Aiden Corvin, Siobhan Schwaiger, Jeanne Marie Nangle, Gary Donohoe, Michael Gill, Derek W. Morris
Publikováno v:
Neuroscience letters. 431(2)
Delineating relationships between susceptibility genes and clinical symptoms may be an important step in understanding the genetics of psychosis. Recent data suggests that the gene dysbindin (DTNBP1) may confer susceptibility across psychotic disorde
Publikováno v:
Neuroscience letters. 412(2)
Tryptophan Hydroxylase 2 (TPH2) is the rate-limiting enzyme in the biosynthesis of serotonin which is exclusively expressed in the brain. Recent molecular studies reported significant association between markers mapped to TPH2 and psychiatric conditi