Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jean-Jacques Martin"'
Autor:
Marc Cruts, Albert Hofman, Geert Van Gassen, A. Wehnert, H Backhovens, Thomas Karlsson, Jessie Theuns, Jean-Jacques Martin, Sheng Yue Wang, Christine Van Broeckhoven, Rolf Adolfsson, Cornelia M. van Duijn
Publikováno v:
Neuroscience letters
Linkage analysis studies have indicated that the chromosome band 14q24.3 harbours a major gene for familial early-onset Alzheimer's disease (AD). Recently we localized the chromosome 14 AD gene (AD3) in the 6.4 cM interval between the markers D14S289
Publikováno v:
Neuroscience letters
A major gene for familial early-onset Alzheimer's disease (AD) has been localised to chromosome 14q24.3. The c-fos gene (FOS), localised to 14q24.3-q31, is a candidate for the AD gene since it may be involved in the transcription regulation of the am
Autor:
Patrick Cras, Jean-Jacques Martin, Inge Vanderhoeven, Christine Van Broeckhoven, Chris De Jonghe
Publikováno v:
Neuroscience letters
Presenilin-1 (PSEN1) mutations I143T and G384A give rise to severe early onset Alzheimers's disease in two extensively studied Belgian families, AD/A and AD/B. In this study we investigated the influence of the I143T and G384A mutations on PSEN1 prot
Autor:
Jean-Jacques Martin, Joke Beuten, Vincent Timmerman, Peter De Jonghe, Christine Van Broeckhoven, Els De Vriendt
Publikováno v:
Neuroscience letters
Molecular genetic analysis in a Belgian family with distal hereditary motor neuropathy type II (distal HMN II), demonstrated significant linkage of markers located at chromosome 12q24. The candidate region, extending from D12S86 to D12S340, includes
Autor:
H. Houlden, Marc Cruts, Richard Crook, Christine Van Broeckhoven, Jean Jacques Martin, H Backhovens, John Hardy
Publikováno v:
Neuroscience letters
A recent study has demonstrated an association of the apolipoprotein E allele ɛ4 (APOE*4) to familial and sporadic late-onset Alzheimer's disease (AD). Also, in late-onset AD families linked to chromosome 19, the onset age decreased when the number