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Autor:
Fei Luo, Huantao Wen, Qiang Wang, Wangming Zhang, Ning Wang, Nanxiang Li, Chen Jiazhi, Huang Shujie, Min Li, Yuzheng Wang, Jin-Yan Wang, Junbin Cai, Siyuan Lv
Publikováno v:
Neurosci Bull
Excessive theta (θ) frequency oscillation and synchronization in the basal ganglia (BG) has been reported in elderly parkinsonian patients and animal models of levodopa (L-dopa)-induced dyskinesia (LID), particularly the θ oscillation recorded duri
Autor:
Li Hu, Jian Cai, Yinggang Sun, Jiaxiang Wu, Fuxue Chen, Jijiang Wang, Shutian Zhang, Kokwin Ooi, Xuehai Wu, Danian Zhu, Chunmei Xia
Publikováno v:
Neuroscience Bulletin
Increased microglial activation and neuroinflammation within autonomic brain regions such as the rostral ventrolateral medulla (RVLM) have been implicated in stress-induced hypertension (SIH). Prorenin, a member of the brain renin-angiotensin system
Autor:
Xiang-Yang Xu, Yao Zhang, Teng Xu, Jun Hu, Shao-Juan Yang, Si Jin, Jian-Zhi Wang, Jia-Zhao Xie
Publikováno v:
Neurosci Bull
Hyperhomocysteinemia (Hhcy) is an independent risk factor for Alzheimer’s disease (AD), and insulin-resistance is commonly seen in patients with Hhcy. Liraglutide (Lir), a glucagon-like peptide that increases the secretion and sensitivity of insuli
Autor:
Wei Cui, Yi-Kang Hou, Guo-Qing Zhu, Hong-Bao Li, Bin Liang, Ying Li, Wen-Jie Xia, Hong-Li Gao, Huiyu Yang, Wensheng Chen, Ya-Nan Zhao, Zhi-Ming Yang, Qing Su, Yu-Ming Kang, Xiao-Jing Yu, Kai-Li Liu
Publikováno v:
Neuroscience Bulletin. 35:57-66
Metformin (MET), an antidiabetic agent, also has antioxidative effects in metabolic-related hypertension. This study was designed to determine whether MET has anti-hypertensive effects in salt-sensitive hypertensive rats by inhibiting oxidative stres
Publikováno v:
Neurosci Bull
Publikováno v:
Neuroscience Bulletin
The present study was designed to investigate the mechanisms by which P2X7 receptors (P2X7Rs) mediate the activation of vasopressinergic neurons thereby increasing sympathetic hyperactivity in the paraventricular nucleus (PVN) of the hypothalamus of
Publikováno v:
Neuroscience Bulletin. 34:457-464
Gamma band oscillation (GBO) and sensory gating (SG) are associated with many cognitive functions. Ketamine induces deficits of GBO and SG in the prefrontal cortex (PFC). However, the time-courses of the effects of different doses of ketamine on GBO
Publikováno v:
Neurosci Bull
In the present study, we investigated the mechanisms underlying the mediation of iron transport by L-type Ca(2+) channels (LTCCs) in primary cultured ventral mesencephalon (VM) neurons from rats. We found that co-treatment with 100 µmol/L FeSO(4) an
Publikováno v:
Neurosci Bull
Neuronal oscillations in the hippocampus are critical for many brain functions including learning and memory. The underlying mechanism of oscillation generation has been extensively investigated in terms of chemical synapses and ion channels. Recentl
Autor:
Meng Zhang, Yun-Feng Li, Meng-Meng Zhou, You Wan, Yuxin Yin, Honghai Wu, Feng-Yu Liu, Jia Liu, Ming Yi, Yanning Hou, Lemin Zheng
Publikováno v:
Neuroscience Bulletin. 32:311-322
Neurosteroids are synthesized in the nervous system from cholesterol or steroidal precursors imported from peripheral sources. These compounds are important allosteric modulators of γ-aminobutyric acid A receptors (GABAARs), which play a vital role