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Autor:
Jolie Danial, Cecilia Bull, Olena Prykhodko, Dilip Kumar Malipatlolla, Marie Kalm, Rukaya Naama Walid, Spandana Masuram, Yohanna Eriksson, Sravani Devarakonda, Rita Grandér, Gunnar Steineck, Margareta Nyman, Ana Rascón, Ella Ittner, H. Georg Kuhn, Fei Sjöberg, Piyush M. Patel
Publikováno v:
Neuroscience. 475:137-147
We sought to determine whether radiation to the colorectum had an impact on parameters of hippocampal neurogenesis and, if so, whether it could be modulated by a fiber-rich diet. Male C57BL/6J mice were fed a diet containing bioprocessed oat bran or
Autor:
Amir Ghanbari, Seyyed Behnamodin Jame'ei, Parichehr Pasbakhsh, Zeinab Namjoo, Kazem Zibara, Showan Amani, Roya Aryanpour, Iraj Ragerdi Kashani, Reza Mahmoudi
Publikováno v:
Neuroscience. 463:116-127
Estrogen produces a beneficial role in animal models of multiple sclerosis (MS). The effect of 17β-estradiol therapy on microglia polarization and neuroinflammation in the corpus callosum of the cuprizone-induced demyelination model has not been elu
Publikováno v:
Neuroscience
Neuroscience, Elsevier-International Brain Research Organization, 2021, 453, pp.1-16. ⟨10.1016/j.neuroscience.2020.11.031⟩
Neuroscience, Elsevier-International Brain Research Organization, 2021, 453, pp.1-16. ⟨10.1016/j.neuroscience.2020.11.031⟩
International audience; A fundamental task for the auditory system is to process communication sounds according to their behavioral significance. In many mammalian species, pup calls became more significant for mothers than other conspecific and hete
Effects of Housing Conditions and Circadian Time on Baseline c-Fos Immunoreactivity in C57BL/6J Mice
Publikováno v:
Neuroscience
Analysis of expression of the immediate early gene c-Fos in neuronal populations is a commonly used method to assess changes in neuronal activity due to various factors of interest. However, different levels of c-Fos have been observed between contro
Autor:
Yong Huang, Nozomi Hishikawa, Toru Yamashita, Jingwei Shang, Yasuyuki Ohta, Kota Sato, Xia Liu, Xiaowen Shi, Mami Takemoto, Yumiko Nakano, Tian Feng, Ryuta Morihara, Koji Abe
Publikováno v:
Neuroscience. 416:126-136
Alzheimer's disease (AD) in the elderly is frequently accompanied by chronic cerebral hypoperfusion (CCH), which impairs the clearance of amyloid beta (Aβ) due to the dysfunction of the blood–brain barrier (BBB) and accelerates the AD pathology. S
Autor:
Keiichiro Tsunoda, Xiaowen Shi, Jingwei Shang, Toru Yamashita, Kota Sato, Mami Takemoto, Koji Abe, Yasuyuki Ohta, Namiko Matsumoto, Tian Feng, Nozomi Hishikawa, Xia Liu, Takahiro Kuchimaru, Ryo Sasaki, Emi Nomura, Koh Tadokoro, Shinae Kizaka-Kondoh
Publikováno v:
Neuroscience. 415:31-43
Hypoxia inducible factor-1α (HIF-1α) is a key transcription factor that maintains oxygen homeostasis. Hypoxic stress is related to the pathogenesis of amyotrophic lateral sclerosis (ALS), and impaired HIF-1α induces motor neuron degeneration in AL
Publikováno v:
Neuroscience. 481
Microglia serve as resident immune cells in the brain, responding to insults and pathological developments. They have also been implicated in shaping synaptic development and regulation. The present study examined microglial cell density in a number
Autor:
Jacqueline L. Vanderluit, Michiru Hirasawa, Kathleen E. Fifield, Joanna B. Raman-Nair, Todd M. Rowe
Publikováno v:
Neuroscience. 406:637-652
Obesity is associated with worse neurological outcomes following overt ischemic strokes. The majority of strokes however, are covert, small strokes that often evade detection. How obesity impacts the cellular response to covert strokes is unclear. He
Autor:
María Paula Cornejo, Franco Barrile, Mirta Reynaldo, Pablo Nicolás de Francesco, Mario Perello, Enrique Leo Portiansky
Publikováno v:
Neuroscience. 392:107-120
Ghrelin is a stomach-derived hormone that regulates rewarding behaviors and reinforcement by acting on the ventral tegmental area (VTA). The VTA is a complex midbrain structure mainly comprised of dopamine (DA) and gamma-aminobutiric acid (GABA) neur
Publikováno v:
Neuroscience. 388:448-459
Anxiety disorder is a major psychiatric disorder characterized by fear, worry, and excessive rumination. However, the molecular mechanisms underlying neural plasticity and anxiety remain unclear. Here, we utilized a mouse model of anxiety-like behavi