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Autor:
Michelle Roche, John P. Kelly, Aoife M. Thornton, Karen Smith, David P. Finn, Connie Sanchez, Daniel M. Kerr, Edel Hughes
Publikováno v:
Neuroscience. 444:9-18
The kappa opioid receptor (KOP) system modulates social play responding, however a paucity of studies have examined effects on social motivation and cognition in the absence of play. Prenatal exposure to the anti epileptic and mood stabiliser valproi
Autor:
Koh Shinoda, Yuya Sakimoto, Akie Yanai, Kanako Nozaki, Dai Mitsushima, Abu Md Mamun Tarif, Mir Rubayet Jahan, Koh-hei Masumoto, Nabiul Islam, Mako Ishida
Publikováno v:
Neuroscience. 440:15-29
Androgen receptor (AR) is abundantly expressed in the preoptico-hypothalamic area, bed nucleus of stria terminalis, and medial amygdala of the brain where androgen plays an important role in regulating male sociosexual, emotional and aggressive behav
Publikováno v:
Neuroscience. 440:196-209
Patients suffering with functional somatic pain syndromes such as temporomandibular disorders (TMD) and fibromyalgia syndrome (FMS) have some similar symptoms, but the underlying cause is still unclear. The purpose of this study was to investigate wh
Autor:
Jolanta Konieczny, Tomasz Lenda, Krystyna Ossowska, Klemencja Berghauzen-Maciejewska, Barbara Kosmowska, Jadwiga Wardas
Publikováno v:
Neuroscience. 429:106-118
The primary cause of harmaline tremor, which is a model of essential tremor (ET) in animals, is excessive activation of olivocerebellar glutamatergic climbing fibers. Our recent study indicated that 5′-chloro-5′-deoxy-(±)-N6-(±)-(endo-norborn-2
Publikováno v:
Neuroscience.
Ambient temperature changes trigger plastic biological responses. Cold temperature is detected by the somatosensory system and evokes perception of cold together with adaptive physiological responses. We addressed whether chronic cold exposure induce
Publikováno v:
Neuroscience
Dysregulation of GABAergic system is becoming increasingly associated with depression, psychiatric disorder that imposes severe clinical, social and economic burden. Special attention is paid to the fast-spiking parvalbumin-positive (PV+) interneuron
Publikováno v:
Neuroscience. 347:22-35
Synaptic pruning underlies the transition from an immature to an adult CNS through refinements of neuronal circuits. Our recent study indicates that pubertal synaptic pruning is triggered by the inhibition generated by extrasynaptic α4βδ GABA A re
Publikováno v:
Neuroscience. 339:525-537
The mesolimbic dopamine and opioid systems are postulated to influence the central control of physical activity motivation. We utilized selectively bred rats for high (HVR) or low (LVR) voluntary running behavior to examine (1) inherent differences i
Autor:
Megumi Ikegami, Chrismawan Ardianto, Junzo Kamei, Lizhe Yang, Hiroshi Nagase, Naomi Yonemochi, Takahiro Ohashi, Hiroko Ikeda
Publikováno v:
Neuroscience. 311:9-21
Opioid receptors, especially μ-opioid receptors, in the ventral tegmental area (VTA) and nucleus accumbens (NAcc) are reported to regulate food motivation. However, the roles of μ-, δ- and κ-opioid receptors are not fully understood. Moreover, si
Publikováno v:
Neuroscience. 310:541-548
Phoenixin (PNX) is a 14-amino acid amidated peptide (PNX-14) or an N-terminal extended 20-residue amidated peptide (PNX-20) recently identified in neural and non-neural tissue. Mass spectrometry analysis identified a major peak corresponding to PNX-1