Zobrazeno 1 - 10
of 1 306
pro vyhledávání: ''
Autor:
Claudia Kühne, Osborne F. X. Almeida, Nils C. Gassen, Elmira Anderzhanova, Ioannis Sotiropoulos, Chrysoula Dioli, Anna Pissioti, Mazen R. Harb, Alexandre V. Patchev, C. Catania, Este Leidmaa, Rainer Stoffel, Shuang Yu, Mary Gazea, Susanne Moosecker
Publikováno v:
Neuroscience. 479:91-106
Like other members of the superfamily of nuclear receptors, the peroxisome proliferator-activated receptor γ (PPARγ), is a ligand-activated transcription factor known for its insulin-sensitizing actions in the periphery. Despite only sparse evidenc
Autor:
Jolie Danial, Cecilia Bull, Olena Prykhodko, Dilip Kumar Malipatlolla, Marie Kalm, Rukaya Naama Walid, Spandana Masuram, Yohanna Eriksson, Sravani Devarakonda, Rita Grandér, Gunnar Steineck, Margareta Nyman, Ana Rascón, Ella Ittner, H. Georg Kuhn, Fei Sjöberg, Piyush M. Patel
Publikováno v:
Neuroscience. 475:137-147
We sought to determine whether radiation to the colorectum had an impact on parameters of hippocampal neurogenesis and, if so, whether it could be modulated by a fiber-rich diet. Male C57BL/6J mice were fed a diet containing bioprocessed oat bran or
Autor:
Yacouba Diagana, Yassine Chahirou, Aboubaker El Hessni, Ali Ouichou, Abdeljabbar Ennaciri, Adil El Midaoui, Inssaf Berkiks, Abdelhalem Mesfioui, Sidi Mohamed Coulibaly
Publikováno v:
Neuroscience. 476:1-11
Evidence suggests that oxidative stress plays an important role in the development of anxiety and depression. The aim of the present study was to investigate whether methyl donors supplementation could exert beneficial effects on hippocampal oxidativ
Publikováno v:
Neuroscience. 472:157-166
Status epilepticus (SE) is a life-threatening neurological disorder that causes neuronal death and glial activation. Studies have explained the clinical side effects and lack of effectiveness of neurological disorder treatments based on sex-related d
Publikováno v:
Neuroscience
Selective serotonin reuptake inhibitor (SSRI) antidepressants are widely prescribed to pregnant women suffering with depression, although the long-term impact of these medications on exposed offspring are poorly understood. Perinatal SSRI exposure al
Autor:
Anna A. Kovalenko, Alexander P. Schwarz, Maria V Zakharova, Olga E. Zubareva, Tatiana Y. Postnikova, Aleksey V. Zaitsev
Publikováno v:
Neuroscience. 468:1-15
Acute seizures can severely affect brain function and development. However, the underlying pathophysiological mechanisms are still poorly understood. Disturbances of the glutamatergic system are considered one of the critical mechanisms of neurologic
Publikováno v:
Neuroscience. 466:148-161
Anesthesia and surgery are associated with perioperative neurocognitive disorders (PND). Dexmedetomidine is known to improve PND in rats; however, little is known about the mechanisms. Male Sprague-Dawley rats were subjected to resection of the hepat
Publikováno v:
Neuroscience. 463:216-226
Objective: Cognitive dysfunction often accompanies diabetes. Both hypoglycemia and hyperglycemia cause cognitive dysfunctions. However, the underlying pathophysiology remains unclear. Recent evidence show that ferroptosis primarily triggers nerve cel
Publikováno v:
Neuroscience. 463:238-253
Clinical studies clearly indicate that early-life stress (ELS) may cause physical and mental health problems later in life. Therefore, the identification of universal biomarkers of ELS-related diseases is very important. The 70-kDa heat shock protein
Autor:
Nuno Sousa, Ioannis Sotiropoulos, Vasilios Kafetzopoulos, Christina Dalla, Katerina Antoniou, Nikolaos Kokras
Publikováno v:
Neuroscience. 454:85-93
The hippocampus-prefrontal cortex circuit plays a major role in stress and in the neurobiology of depression and its treatment. Disruption of this circuit by lesioning the thalamic nucleus reuniens (RE) has been shown to prevent the detrimental effec