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Publikováno v:
Neuroscience
Sex differences in METH use exist among human METH users and in animal models of METH addiction. Herein, we tried to identify potential differences in gene expression between female and male rats after Methamphetamine self-administration (METH SA). R
Publikováno v:
Neuroscience
Highlights • Human hippocampal progenitor cells (HPCs) and tissue express classical sex hormone receptors. • Prolactin does not impact human HPCs maintained in a proliferative state. • Prolactin increases neuronal differentiation of human HPCs
Autor:
Sanjay Kumar, Stephen Beesley, Cameron D’Orio, Roshan Ailani, Mathew S. Crockett, Thomas Sullenberger
Publikováno v:
Neuroscience
Entrainment of the hippocampus by the medial entorhinal area (MEA) in Temporal Lobe Epilepsy (TLE), the most common type of drug-resistant epilepsy in adults, is believed to be mediated primarily through the perforant pathway (PP), which connects ste
Autor:
Koh Shinoda, Yuya Sakimoto, Akie Yanai, Kanako Nozaki, Dai Mitsushima, Abu Md Mamun Tarif, Mir Rubayet Jahan, Koh-hei Masumoto, Nabiul Islam, Mako Ishida
Publikováno v:
Neuroscience. 440:15-29
Androgen receptor (AR) is abundantly expressed in the preoptico-hypothalamic area, bed nucleus of stria terminalis, and medial amygdala of the brain where androgen plays an important role in regulating male sociosexual, emotional and aggressive behav
Autor:
Rafael Moura Maurmann, Pauline Maciel August, Karoline Dos Santos Rodrigues, Mariana Crestani Scortegagna, Cristiane Matté, B.G. dos Santos, Régis Hözer
Publikováno v:
Neuroscience. 437:196-206
Physical exercise practice has been increasingly recommended in the prevention and treatment of chronic diseases, causing a positive effect from body weight/fat loss to improved cognitive function. Maternal exercise seems to induce the same positive
Autor:
Hasan Alhaddad, Terry D. Hinds, Richard L. Bell, Darren M. Gordon, Youssef Sari, Erin Jarvis, Zachary A. Kipp
Publikováno v:
Neuroscience
Evidence suggests the hypothalamic–pituitary–adrenal (HPA) axis is involved in Alcohol Use Disorders (AUDs), which might be mediated by an imbalance of glucocorticoid receptor (GR), GRα and GRβ, activity. GRβ antagonizes the GRα isoform to ca
Publikováno v:
Neuroscience
Fetal alcohol spectrum disorders (FASD) constitute a prevalent, yet preventable, developmental disorder worldwide. While a wealth of research demonstrates that altered function of hippocampus and prefrontal cortex may underlie behavioral impairments
Publikováno v:
Neuroscience. 432:126-136
Post-traumatic stress disorder (PTSD) patients exhibit abnormal learning and memory. Axons from orexin neurons in the lateral hypothalamus innervate the hippocampus, modulating learning and memory via the orexin 1 and 2 receptors (OX1R and OX2R). How
Autor:
Ari L. Mendell, Kristen H. Jardine, Boyer D. Winters, Neil J. MacLusky, Samantha D. Creighton, Lauren Isaacs, Hayley A. Wilson
Publikováno v:
Neuroscience. 429:185-202
Recent work has suggested that 5α-reduced metabolites of testosterone may contribute to the neuroprotection conferred by their parent androgen, as well as to sex differences in the incidence and progression of Alzheimer’s disease (AD). This study
Publikováno v:
Neuroscience. 428:140-153
Posttraumatic epilepsy (PTE) is a long-term negative consequence of traumatic brain injury (TBI) in which recurrent spontaneous seizures occur after the initial head injury. PTE develops over an undefined period during which circuitry reorganization