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Autor:
Jolie Danial, Cecilia Bull, Olena Prykhodko, Dilip Kumar Malipatlolla, Marie Kalm, Rukaya Naama Walid, Spandana Masuram, Yohanna Eriksson, Sravani Devarakonda, Rita Grandér, Gunnar Steineck, Margareta Nyman, Ana Rascón, Ella Ittner, H. Georg Kuhn, Fei Sjöberg, Piyush M. Patel
Publikováno v:
Neuroscience. 475:137-147
We sought to determine whether radiation to the colorectum had an impact on parameters of hippocampal neurogenesis and, if so, whether it could be modulated by a fiber-rich diet. Male C57BL/6J mice were fed a diet containing bioprocessed oat bran or
Publikováno v:
Neuroscience. 472:157-166
Status epilepticus (SE) is a life-threatening neurological disorder that causes neuronal death and glial activation. Studies have explained the clinical side effects and lack of effectiveness of neurological disorder treatments based on sex-related d
Autor:
Anna A. Kovalenko, Alexander P. Schwarz, Maria V Zakharova, Olga E. Zubareva, Tatiana Y. Postnikova, Aleksey V. Zaitsev
Publikováno v:
Neuroscience. 468:1-15
Acute seizures can severely affect brain function and development. However, the underlying pathophysiological mechanisms are still poorly understood. Disturbances of the glutamatergic system are considered one of the critical mechanisms of neurologic
Publikováno v:
Neuroscience. 463:216-226
Objective: Cognitive dysfunction often accompanies diabetes. Both hypoglycemia and hyperglycemia cause cognitive dysfunctions. However, the underlying pathophysiology remains unclear. Recent evidence show that ferroptosis primarily triggers nerve cel
Autor:
Koh Shinoda, Yuya Sakimoto, Akie Yanai, Kanako Nozaki, Dai Mitsushima, Abu Md Mamun Tarif, Mir Rubayet Jahan, Koh-hei Masumoto, Nabiul Islam, Mako Ishida
Publikováno v:
Neuroscience. 440:15-29
Androgen receptor (AR) is abundantly expressed in the preoptico-hypothalamic area, bed nucleus of stria terminalis, and medial amygdala of the brain where androgen plays an important role in regulating male sociosexual, emotional and aggressive behav
Publikováno v:
Neuroscience
Fetal alcohol spectrum disorders (FASD) constitute a prevalent, yet preventable, developmental disorder worldwide. While a wealth of research demonstrates that altered function of hippocampus and prefrontal cortex may underlie behavioral impairments
Publikováno v:
Neuroscience. 428:140-153
Posttraumatic epilepsy (PTE) is a long-term negative consequence of traumatic brain injury (TBI) in which recurrent spontaneous seizures occur after the initial head injury. PTE develops over an undefined period during which circuitry reorganization
Autor:
Yong Huang, Nozomi Hishikawa, Toru Yamashita, Jingwei Shang, Yasuyuki Ohta, Kota Sato, Xia Liu, Xiaowen Shi, Mami Takemoto, Yumiko Nakano, Tian Feng, Ryuta Morihara, Koji Abe
Publikováno v:
Neuroscience. 416:126-136
Alzheimer's disease (AD) in the elderly is frequently accompanied by chronic cerebral hypoperfusion (CCH), which impairs the clearance of amyloid beta (Aβ) due to the dysfunction of the blood–brain barrier (BBB) and accelerates the AD pathology. S
Publikováno v:
Neuroscience. 415:18-30
Previous studies have focused on the effects of N-methyl-D-aspartate receptor (NMDAR) blockade on neonates, but little is known about the effect of the embryonic NMDAR blockade on offspring, especially the long-lasting effect, on behavior in adulthoo
Publikováno v:
Neuroscience. 481
Microglia serve as resident immune cells in the brain, responding to insults and pathological developments. They have also been implicated in shaping synaptic development and regulation. The present study examined microglial cell density in a number