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Autor:
Ali Akbar Owji, Mohammad Ali Takhshid, Farideh Jalali Mashayekhi, Zahra Khoshdel, Somayeh Ahmadpour Jirandeh, Shahla Shojaei
Publikováno v:
Neuroscience. 422:54-64
The pancreatic peptide, Amylin (AMY), reportedly affects nociception in rodents. Here, we investigated the potential effect of AMY on the tolerance to morphine and on the expression of BDNF at both levels of protein and RNA in the lumbar spinal cord
Autor:
Gerald J. Obermair, M Urbanek, K Wegleiter, Ursula Kiechl-Kohlendorfer, Ruslan Stanika, Karina Wechselberger, Elke Griesmaier, Anna Posod, Eva Huber
Publikováno v:
Neuroscience. 352:88-96
Neonatal brain injury is a problem of global importance. To date, no causal therapies are available. A substance with considerable therapeutic potential is the endogenous neuropeptide secretoneurin (SN), which has proven to be beneficial in adult str
Autor:
Helena Domin, Danuta Jantas, Maria Śmiałowska, Łukasz Przykaza, Ewa Kozniewska, Paweł M. Boguszewski
Publikováno v:
Neuroscience. 344:305-325
It was postulated that neuropeptide Y (NPY)-ergic system could be involved in the ischemic pathophysiology, however, the role of particular subtypes of NPY receptors (YRs) in neuroprotection against ischemia is still not well known. Therefore, we inv
Autor:
Anna M. Czarnecka, Jolanta Konieczny, Lucyna Antkiewicz-Michaluk, Tomasz Lenda, Kinga Kamińska
Publikováno v:
Neuroscience. 340:308-318
A growing body of evidence indicates that impairment of the ubiquitin-proteasome (UPS) system in the substantia nigra (SN) plays an important role in the pathogenesis of Parkinson's disease (PD). The aim of our study was to compare two unilateral rat
Autor:
A. Haj-Mirzaian, S. Amiri, N. Kordjazy, M. Momeny, A. Razmi, M. Rahimi-Balaei, H. Amini-Khoei, H. Marzban, S.E. Mehr, S.H. Ghaffari, A.R. Dehpour
Publikováno v:
Neuroscience. 315:271-285
The neuroimmune-endocrine dysfunction has been accepted as one of fundamental mechanisms contributing to the pathophysiology of psychiatric disorders including depression and anxiety. In this study, we aimed to evaluate the involvement of hypothalami
Publikováno v:
Neuroscience. 311:130-137
The present study was to investigate whether baicalin can prevent repeated exogenous corticosterone injection-induced depressive-like behaviors and explore its possible mechanisms. After a 21-day treatment with baicalin (10 and 20 mg/kg), sucrose pre
Autor:
Qiao-Jun Zhang, H.H. Tan, Ling Zhang, X.L. Niu, Cheng-Xue Du, Li Bo Li, Jian-Xin Liu, Jiye Zhang
Publikováno v:
Neuroscience. 311:45-55
The role of serotonin7 (5-HT7) receptors in the regulation of depression is poorly understood, particularly in Parkinson's disease-associated depression. Here we examined whether 5-HT7 receptors in the prelimbic (PrL) sub-region of the ventral medial
Publikováno v:
Neuroscience. 305:225-237
Two neuropeptides, orexin-A and orexin-B (also called hypocretin-1 and -2), have been implicated in sleep/wake regulation, feeding behaviors via the activation of two subtypes of G-protein-coupled receptors: orexin 1 and orexin 2 receptors (OX1R and
Autor:
G.F. Da Silva, Mogens L. Glass, Norberto Garcia-Cairasco, T. de Oliveira Sergio, Ailton Spiacci, Hélio Zangrossi, Luiz Carlos Schenberg
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
It has been proposed that spontaneous panic attacks are the outcome of the misfiring of an evolved suffocation alarm system. Evidence gathered in the last years is suggestive that the dorsal periaqueductal gray (dPAG) in the midbrain harbors a hypoxi
Publikováno v:
Neuroscience. 300:53-62
Ghrelin is a potent orexigenic hormone that acts in the central nervous system to stimulate food intake via the growth hormone secretagogue receptor (GHSR) that is abundantly expressed in the ventral tegmental area (VTA). Not only does ghrelin modula