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Publikováno v:
Neuroscience. 167:741-749
The estrogen-mimicking endocrine disrupter bisphenol A (BPA) which is used in the manufacture of plastic and epoxy resins, is one of the world's most heavily produced synthetic chemicals. BPA is detected in animal tissues, and its bio-accumulation ha
Publikováno v:
Neuroscience. 167:920-928
The perifornical-lateral hypothalamic area (PF-LHA) has been implicated in the regulation of behavioral arousal. The PF-LHA predominantly contains neurons that are active during behavioral and cortical activation and quiescent during non-rapid eye mo
Publikováno v:
Neuroscience. 166:1158-1166
Platelet-activating factor (PAF) is an important inflammatory lipid mediator affecting neural plasticity. In the present study, we demonstrated how PAF affects synaptic efficacy through activation of protein kinases in the rat hippocampal CA1 region.
Autor:
Jana Sánchez-Wandelmer, G. de la Pena, Alberto Canfrán-Duque, Franz Bracher, Miguel A. Lasunción, Antonia Martín-Hidalgo, Alberto Dávalos, Martin Giera, Rebeca Busto, Sonia Cano, Carlos Fernández-Hernando
Publikováno v:
Sánchez-Wandelmer, J, Dávalos, A, de la Peña, G, Cano, S, Giera, M A, Canfrán-Duque, A, Bracher, F, Martín-Hidalgo, A, Fernández-Hernando, C, Lasunción, M A & Busto, R 2010, ' Haloperidol disrupts lipid rafts and impairs insulin signaling in SH-SY5Y cells ', Neuroscience, vol. 167, no. 1, pp. 143-153 . https://doi.org/10.1016/j.neuroscience.2010.01.051
Neuroscience, 167(1), 143-153. Elsevier Limited
Neuroscience, 167(1), 143-153. Elsevier Limited
Haloperidol exerts its therapeutic effects basically by acting on dopamine receptors. We previously reported that haloperidol inhibits cholesterol biosynthesis in cultured cells. In the present work we investigated its effects on lipid-raft compositi
Publikováno v:
Neuroscience. 166:1194-1209
Tinnitus, also called phantom auditory perception, is a major health problem in western countries. As such, a significant amount of effort has been devoted to understanding its mechanisms, including studies in animals wherein a supposed "tinnitus sta
Publikováno v:
Neuroscience. 167:174-184
The protective effect of an iridoid catalpol extracted and purified from the traditional Chinese medicinal herb Rehmannia glutinosa on the neuronal degeneration of nigral-striatal dopaminergic pathway was studied in a chronic 1-methyl-4-phenyl-1,2,3,
Autor:
Tetsuro Ishii, Eiji Warabi, Akira Hara, Keiko Oikawa, Katsuhiko Tabuchi, Shuho Tanaka, Kentaro Hayashi, Toru Yanagawa, Bungo Nishimura, Tomofumi Hoshino
Publikováno v:
Neuroscience. 166:665-670
This study evaluated the protective role of p38 mitogen-activated protein kinase (p38 MAPK) inhibitors and sequestosome 1 (Sqstm1/A170/p62), a stress-induced signal modulator, in acoustic injury of the cochlea in mice. Two weeks after the exposure of
Publikováno v:
Neuroscience. 165:1429-1438
Amylin is a member of calcitonin or calcitonin gene-related peptide (CGRP) family. Immunohistochemical study revealed a dense network of amylin-immunoreactive (irAMY) cell processes in the superficial dorsal horn of the mice. Numerous dorsal root gan
Autor:
David N. Linsenbardt, Stephen L. Boehm
Publikováno v:
Neuroscience. 164:424-434
Recent studies have indicated a role for the endocannabinoid system in the behavioral and physiological effects of alcohol (ethanol), particularly ethanol seeking behaviors. However, its role in modulating binge-like intake and/or the mechanism by wh
Publikováno v:
Neuroscience. 164:667-675
Neuroinflammation of the CNS seems to participate in sensitizing effects of drugs of abuse such as psychostimulants and morphine. The nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha) plays a prominent role in several phy