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Autor:
Kimberly E. Iceman, Michael E. Harris
Publikováno v:
Neuroscience. 259:203-213
Serotonin/substance P synthesizing cells in the raphé nuclei of the brain are candidates for designation as central chemoreceptors that are stimulated by CO2/pH. We have previously demonstrated that these neurons are CO2-stimulated in situ. Evidence
Publikováno v:
Neuroscience. 259:53-62
Sensory input from the temporomandibular joint (TMJ) to neurons in superficial laminae at the spinomedullary (Vc/C 1–2 ) region is strongly influenced by estrogen status. This study determined if GABAergic mechanisms play a role in estrogen modulat
Publikováno v:
Neuroscience. 257:65-75
Progesterone is a known anticonvulsant, with its inhibitory effects generally attributed to its secondary metabolite, 5α,3α-tetrahydroprogesterone (THP), and THP's enhancement of GABAA receptor activity. Accumulating evidence, however, suggests tha
Publikováno v:
Neuroscience. 253:245-255
GABA is thought to function as a paracrine factor in adrenal medullary (AM) cells. Thus, we electrophysiologically and immunologically examined the properties of GABA A receptors (GABA A Rs) in guinea-pig AM cells. Bath application of GABA produced a
Publikováno v:
Neuroscience. 201:157-165
Glucose-sensitive neurons have been identified in a number of CNS regions including metabolic control centers of the hypothalamus. The location of these regions behind the blood-brain barrier restricts them to sensing central, but not circulating glu
Publikováno v:
Neuroscience. 167:920-928
The perifornical-lateral hypothalamic area (PF-LHA) has been implicated in the regulation of behavioral arousal. The PF-LHA predominantly contains neurons that are active during behavioral and cortical activation and quiescent during non-rapid eye mo
Publikováno v:
Neuroscience. 166:1194-1209
Tinnitus, also called phantom auditory perception, is a major health problem in western countries. As such, a significant amount of effort has been devoted to understanding its mechanisms, including studies in animals wherein a supposed "tinnitus sta
Autor:
Qiao-Jun Zhang, Yi Wang, Shouyang Wang, Wu Zhongheng, Li Chen, Jian-xin Liu, Z.H. Gui, Tingzhong Wang
Publikováno v:
Neuroscience. 159:850-861
Several studies have shown that the 5-hydroxytryptamine (serotonin, 5-HT) system is severely affected after degeneration of nigrostriatal dopaminergic neurons. In the present study, we examined the changes in the firing rate and firing pattern of the
Autor:
David L. Hill, J.E. Thomas
Publikováno v:
Neuroscience. 157:329-339
Prenatal dietary sodium restriction produces profound developmental effects on rat functional taste responses and formation of neural circuits in the brainstem. Converging evidence indicates that the underlying mechanisms for these effects are relate
Publikováno v:
Neuroscience. 157:414-423
Recent studies suggest that tumor necrosis factor-alpha (TNF) sensitizes primary afferent neurons, and thus facilitates neuropathic pain. Here, we separately examined the roles of tumor necrosis factor receptor (TNFR) 1 and 2 by parallel in vivo and