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Autor:
Claudia Kühne, Osborne F. X. Almeida, Nils C. Gassen, Elmira Anderzhanova, Ioannis Sotiropoulos, Chrysoula Dioli, Anna Pissioti, Mazen R. Harb, Alexandre V. Patchev, C. Catania, Este Leidmaa, Rainer Stoffel, Shuang Yu, Mary Gazea, Susanne Moosecker
Publikováno v:
Neuroscience. 479:91-106
Like other members of the superfamily of nuclear receptors, the peroxisome proliferator-activated receptor γ (PPARγ), is a ligand-activated transcription factor known for its insulin-sensitizing actions in the periphery. Despite only sparse evidenc
Publikováno v:
Neuroscience. 468:199-210
Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a crucial regulator of neuronal development, neuronal survival, axonal regeneration, and synaptic plasticity. In this study we examined the potential role of PTEN in cognitive functio
Autor:
Aubrey M. Kelly, Ashley W. Seifert
Publikováno v:
Neuroscience
The nonapeptides vasopressin (VP) and oxytocin (OT) are present in some form in most vertebrates. VP and OT play critical roles in modulating physiology and are well-studied for their influences on a variety of social behaviors, ranging from affiliat
Publikováno v:
Neuroscience. 466:148-161
Anesthesia and surgery are associated with perioperative neurocognitive disorders (PND). Dexmedetomidine is known to improve PND in rats; however, little is known about the mechanisms. Male Sprague-Dawley rats were subjected to resection of the hepat
Autor:
Claire E. Manning, Vedrana Bali, Shantée N. Ayala Rosario, Minerva Rodriguez, Michelle S. Mazei-Robison, Sarah C. Simmons, Marie A. Doyle, Ali R. Stark, Alfred J. Robison
Publikováno v:
Neuroscience
Despite the high prevalence of major depressive disorder (MDD), understanding of the biological underpinnings remains limited. Rodent models suggest that changes in activity and output of dopamine (DA) neurons in the ventral tegmental area (VTA) are
Autor:
Kimbra A. Edwards, Susan L. Zup
Publikováno v:
Neuroscience. 463:184-196
Neuronal excitability and susceptibility to excitotoxic damage can be sex-specific, with neurons from males usually being more 'easily excitable' compared to neurons from females, especially during development. Increased excitability at an individual
Publikováno v:
Neuroscience
Activation of extracellular signal-regulated kinase 1 and 2 (ERK1/2) signaling in cardiovascular regulatory regions of the brain contributes to sympathetic excitation in myocardial infarction (MI)-induced heart failure (HF) by increasing brain renin-
Autor:
Nima Bakhtiari, Alireza Farnam, Alireza Sarkaki, Seyed Ali Mard, Javad Mahmoudi, Neda Yazdanfar
Publikováno v:
Neuroscience. 461:80-90
Maternal opioids abuse has some deleterious consequences on next generations. Besides, children's rearing conditions can affect the behavioral states and brain plasticity in their later life. In the present study, we investigated the effects of mater
Publikováno v:
Neuroscience
Neuroscience, Elsevier-International Brain Research Organization, 2021, 460, pp.130-144. ⟨10.1016/j.neuroscience.2021.01.015⟩
Neuroscience, Elsevier-International Brain Research Organization, 2021, 460, pp.130-144. ⟨10.1016/j.neuroscience.2021.01.015⟩
International audience; Attentional automatic processes and cerebral activity may differ between individuals with different weight statuses in the presence of food stimuli (e.g. odors, pictures). In the present study, we used an implicit olfactory pr
Autor:
Adam M. Goodman, Douglas A. Granger, David C. Knight, Nathaniel G. Harnett, Sylvie Mrug, Kimberly H. Wood, Muriah D. Wheelock
Publikováno v:
Neuroscience
The prefrontal cortex and limbic system are important components of the neural circuit that underlies stress and anxiety. These brain regions are connected by white matter tracts that support neural communication including the cingulum, uncinate fasc