Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leandro F. Vendruscolo"'
Autor:
Ehsan Shokri-Kojori, Leandro F. Vendruscolo, Corinde E. Wiers, Dardo Tomasi, Ryan E. Tyler, Elizabeth A Cabrera, Tyler Stodden, Gene-Jack Wang, Veronica Ramirez, Clara Freeman, Min Guo, Sukru B. Demiral, Jeih-San Liow, Yeon Joo Jang, Gregg Miller, Cheryl L. Morse, Elsa Lindgren, George F. Koob, Luke Park, Robert B. Innis, Victor W. Pike, Amna Zehra, Sung Won Kim, Nancy Diazgranados, Nora D. Volkow
Publikováno v:
Neuropsychopharmacology
Neuroinflammation appears to contribute to neurotoxicity observed with heavy alcohol consumption. To assess whether chronic alcohol results in neuroinflammation we used PET and [11C]PBR28, a ligand that binds to the 18-kDa translocator protein (TSPO)
Autor:
Emily G. Lowery-Gionta, Janaina C. M. Vendruscolo, Stephanie A. Carmack, Maury Cole, Brooke E. Schmeichel, Olivier George, George F. Koob, Brendan J. Tunstall, Leandro F. Vendruscolo, Sophia A. Vandewater, Michael A. Taffe
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 43, iss 4
Opioid misuse is at historically high levels in the United States, with inhalation (ie, smoking and vaping) being one of the most common routes of consumption. We developed and validated a novel preclinical model of opioid self-administration by inha
Autor:
Joel E. Schlosburg, George F. Koob, Daniel O Hernandez, Leandro F. Vendruscolo, Carrie L. Wade
Publikováno v:
Neuropsychopharmacology. 40:421-428
The abuse of prescription opioids that are used for the treatment of chronic pain is a major public health concern, costing ∼$53.4 billion annually in lost wages, health-care costs, and criminal costs. Although opioids remain a first-line therapy f
Autor:
Leandro F. Vendruscolo, Gery Schulteis, Scott Edwards, Paula E. Park, Jesse R. Schank, Kejun Cheng, Estelle Barbier, Nathan Juergens, George F. Koob, Kaushik K. Misra, Markus Heilig, Kenner C. Rice, Joel E. Schlosburg
Publikováno v:
Neuropsychopharmacology. 38:976-984
Genetic deletion of the neurokinin 1 receptor (NK1R) has been shown to decrease the reinforcing properties of opioids, but it is unknown whether pharmacological NK1R blockade has the same effect. Here, we examined the effect of L822429, a rat-specifi