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Autor:
Nina Donner, Inga D. Neumann
Publikováno v:
Neuroendocrinology. 90:315-322
Chronic intracerebroventricular (icv) infusion of prolactin (PRL) into the cerebral ventricles and mimicking central hyperprolactinemia in lactation has recently been shown to reduce anxiety and neuronal as well as neuroendocrine responses to acute s
Publikováno v:
Neuroendocrinology. 89:200-209
The antiprogesterone mifepristone facilitates prolactin release, an effect enhanced by administration of the opioid antagonist naloxone. The present study explores ultrastructural changes in lactotropes after mifepristone and naloxone administration,
Autor:
Gabriella Uhereczky, Andrej Tillinger, Boris Mravec, Miklós Palkovits, Richard Kvetnansky, György M. Nagy, Ibolya Bodnár
Publikováno v:
Neuroendocrinology. 86:69-76
Subcutaneous injection of diluted formalin (0.2 ml of 4% solution/100 g BW) can influence the increase of plasma epinephrine levels in rats exposed to exteroceptive (handling, immobilization), as well as to interoceptive stressors (insulin-induced hy
Publikováno v:
Neuroendocrinology. 84:58-67
Background/Aims: During late pregnancy, the antiprogesterone mifepristone facilitates prolactin release. This effect is enhanced by administration of the opioid antagonist naloxone, suggesting an inhibitory-neuromodulatory role of the opioid system.
Publikováno v:
Neuroendocrinology. 80:11-20
Using a pharmacological approach, we explored potential mechanisms for the regulation of prolactin secretion by opioid peptides at the end of pregnancy in rats. On day 19 of pregnancy, intracereboventricular administration of the µ-opioid receptor a
Autor:
Oscar Gómez, José A. Balsa
Publikováno v:
Neuroendocrinology. 80:324-331
We have shown that pituitary vasoactive intestinal peptide (VIP) mediates the effects of estrogen on lactotrope hyperplasia, angiogenesis and hyperprolactinemia, and reduces the pituitary content of transforming growth factor beta β1 (TGF-β1, an in
Autor:
Marc E. Freeman, Michael T. Sellix
Publikováno v:
Neuroendocrinology. 77:59-70
Prolactin (PRL) secretion is inhibited by dopamine (DA) released from hypothalamic neuroendocrine neurons designated tuberoinfundibular (TIDA), tuberohypophyseal (THDA) and periventricular hypophyseal (PHDA) dopaminergic (DAergic) neurons. Since PRL
Autor:
Manuel Tena-Sempere, Rafael Alonso, José E. Sánchez-Criado, Carmina Bellido, Rafaela Aguilar, Juana Martín de las Mulas
Publikováno v:
Neuroendocrinology. 77:425-435
Tamoxifen (TX) is an antiestrogen with varying levels of antagonist/agonist activity on the reproductive axis of the rat. It has been reported that TX, in contrast to other selective estrogen receptor modulators (SERMs), increases the content of cyto
Publikováno v:
Neuroendocrinology. 68:172-179
The effects of chronic ovarian steroid treatment on the secretory activity of individual lactotropes and the mechanisms modulating their responsiveness to dopamine (DA) were studied. Female rats were ovariectomized (OVX) and implanted with Silastic c
Publikováno v:
Neuroendocrinology. 67:377-383
Changes in the concentrations of dopamine (DA) and its major metabolite, 3,4-dihydroxyphenylacetic acid (DOPAC), were characterized in the pituitary gland throughout the 4-day estrous cycle of the rat. Female rats were sacrificed at 2- to 3-hour inte