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Autor:
Anna Rita Bentivoglio, Paolo Calabresi, Valerio Brunetti, Pietro Cortelli, Jessica Marotta, Giacomo Della Marca, Carla Piano, Danilo Genovese
Publikováno v:
Neurodegenerative Diseases. 21:79-86
Introduction: Autonomic dysfunction has been reported as one of nonmotor manifestations of both presymptomatic and manifest Huntington’s disease (HD). The aim of our study was to evaluate heart rate variability (HRV) during wake and sleep in a coho
Autor:
René Hurlemann, Oliver Kaut, Tamara Schaprian, Thomas Klockgether, Marcus Grobe-Einsler, Ina R. Vogt
Publikováno v:
Neurodegenerative diseases 20(2-3), 104-109 (2020). doi:10.1159/000510057
Background: Rivastigmine is an acetylcholine esterase inhibitor which is commonly used as therapy for dementia in Alzheimer’s disease and Parkinson’s disease (PD). Recently, a randomized controlled trial demonstrated a positive effect of rivastig
Autor:
Ashfaq Ahmad, Syed Amir Gillani, Humaira Iram, Muhammad Kashif, Asif Hanif, Muhammad Ali Mohseni Bandpei
Publikováno v:
Neurodegenerative Diseases. 20:90-96
Background: Parkinson’s disease (PD) is one of the most common neurological disorders, of insidious onset, with major motor symptomatology including bradykinesia, rest tremor, rigidity, and postural disturbances. Virtual reality (VR) and motor imag
Autor:
Jiadi Xu, Peter C.M. van Zijl, Hanzhang Lu, Wanli W. Smith, Lin Chen, Gongbo Guo, Chunming Gu, Christopher A. Ross, Hongshuai Liu, Jun Hua, Xiaofei He, Peiying Liu, Bo Ning, Wenzhen Duan, Zhiliang Wei, Adnan Bibic
Publikováno v:
Neurodegener Dis
Background: Parkinson’s disease (PD) is the second most common neurodegenerative disease and the most common movement disorder characterized by motor impairments resulting from midbrain dopamine neuron loss. Abnormalities in small pial arteries and
Autor:
Rita Nisticò, Andrea Quattrone, Paola Valentino, Aldo Quattrone, Franco Pucci, Alessia Sarica, Antonio Cerasa, Stefania Barone
Publikováno v:
Neurodegenerative diseases (Online) (2019). doi:10.1159/000503970
info:cnr-pdr/source/autori:Sarica A a, Valentino P c, Nisticò R b, Barone S c, Pucci F c, Quattrone A c, Cerasa A b, Quattrone A a,b/titolo:Assessment of the Corticospinal Tract Profile in Pure Lower Motor Neuron Disease: A Diffusion Tensor Imaging Study./doi:10.1159%2F000503970/rivista:Neurodegenerative diseases (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Sarica A a, Valentino P c, Nisticò R b, Barone S c, Pucci F c, Quattrone A c, Cerasa A b, Quattrone A a,b/titolo:Assessment of the Corticospinal Tract Profile in Pure Lower Motor Neuron Disease: A Diffusion Tensor Imaging Study./doi:10.1159%2F000503970/rivista:Neurodegenerative diseases (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
Aim: The aim of this study was to evaluate the corticospinal tract (CST) diffusion profile in pure lower motor neuron disease (pLMND) patients who at baseline did not show any clinical or electrophysiological involvement of upper motor neurons (UMN),
Autor:
Won Tae Yoon, Jin Whan Cho, Ji Hyun Choi, Jae Woo Kim, Beomseok Jeon, Oh Dae Kwon, Jee Young Lee, Seong Beom Koh, Hyeo Il Ma, Ho-Won Lee, Jong Min Kim, Hee Tae Kim, Jong Sam Baik
Publikováno v:
Neurodegenerative Diseases. 19:171-177
Introduction: Impulse control disorder (ICD) in Parkinson’s disease (PD) is a critical nonmotor symptom with personality or neuropsychiatric traits contributing to ICD. Objective: This study aimed to identify predictive traits for persistent or par
Autor:
Yangyang Duan, Feng Wang, Fengting Zhang, Haining Li, Shaoqing Lin, Andy Li, Hui Li, Luxuan Wang, Guowei Wang
Publikováno v:
Neurodegenerative Diseases. 19:204-210
Background: Parkinson’s disease (PD) is a neurodegenerative disease characterized by intracellular α-synuclein (α-Syn) deposition. Alternation of the α-Syn expression level in plasma or erythrocytes may be used as a potential PD biomarker. Howev
Publikováno v:
Neurodegenerative Diseases. 19:155-162
Introduction: We aimed to investigate the change of serum indirect bilirubin (IBIL) concentrations in patients with Parkinson’s disease (PD) and whether IBIL concentrations were associated with the motor subtypes of PD. Methods: A case-control stud
Publikováno v:
Neurodegenerative Diseases. 19:238-243
Background: Multiple system atrophy (MSA) patients present a variety of symptoms other than autonomic dysfunctions, parkinsonism, and cerebellar ataxia. The aim of this study was to evaluate the frequency of various motor and non-motor symptoms inc
Autor:
Marion Ortner, Scott Miners, Timo Grimmer, Hans Förstl, Robert Perneczky, Janine Diehl-Schmid, Christian Sorg, Alexander Kurz, Igor Yakushev, Oliver Goldhardt
Publikováno v:
Neurodegenerative Diseases. 19:43-50
Background: Neprilysin (NEP) cleaves amyloid-β 1–42 (Aβ42) in the brain. Hence, we aimed to elucidate the effect of NEP on Aβ42 in cerebrospinal fluid (CSF) and on in vivo brain amyloid load using amyloid positron emission tomography (PET) with