Zobrazeno 1 - 10
of 17
pro vyhledávání: ''
Autor:
Won Tae Yoon, Jin Whan Cho, Ji Hyun Choi, Jae Woo Kim, Beomseok Jeon, Oh Dae Kwon, Jee Young Lee, Seong Beom Koh, Hyeo Il Ma, Ho-Won Lee, Jong Min Kim, Hee Tae Kim, Jong Sam Baik
Publikováno v:
Neurodegenerative Diseases. 19:171-177
Introduction: Impulse control disorder (ICD) in Parkinson’s disease (PD) is a critical nonmotor symptom with personality or neuropsychiatric traits contributing to ICD. Objective: This study aimed to identify predictive traits for persistent or par
Publikováno v:
Neurodegenerative Diseases. 19:155-162
Introduction: We aimed to investigate the change of serum indirect bilirubin (IBIL) concentrations in patients with Parkinson’s disease (PD) and whether IBIL concentrations were associated with the motor subtypes of PD. Methods: A case-control stud
Autor:
Ling-Ling Wang, Yiming Liu, Xiaotang Wang, Xiao-Mei Yao, Dong Wang, Tao Yue, Si Chen, Lei Zhang, Zhenxiang Zhao
Publikováno v:
Neurodegenerative Diseases. 17:251-260
Background: Growth differentiation factor 15 (GDF15) has been shown to be protective for dopaminergic neurons in animal and ex vivo experiments. However, little is known about its effect on the human body. Objective: This study investigated associati
Autor:
Ingrid S. Tarr, Roger Pamphlett, Shu Yang, Emily P. McCann, Garth A. Nicholson, Jennifer A. Fifita, Dominic B. Rowe, Ian P. Blair, Alison L. Hogan, Denis C. Bauer, Neil F. W. Saunders, Katharine Y. Zhang, Jasmin Galper, Kelly L. Williams
Publikováno v:
Neurodegenerative Diseases. 17:304-312
Background: Mutations in the genes encoding the heterogeneous nuclear ribonucleoproteins hnRNPA1 and hnRNPA2/B1 have been reported in a multisystem proteinopathy that includes amyotrophic lateral sclerosis (ALS) and inclusion body myopathy associated
Publikováno v:
Neurodegenerative Diseases. 11:1-12
Background: The dysfunction of protein degradation through the ubiquitin-proteasome system is now widely accepted as one of the causes of Alzheimer’s disease (AD), the pathological hallmarks of which are abnormal protein accumulation such as senile
Autor:
Didier Leys, Claude-Alain Maurage, Florence Pasquier, Jacques De Reuck, Charlotte Cordonnier, Vincent Deramecourt
Publikováno v:
Neurodegenerative Diseases. 9:170-175
Background: Cerebrovascular lesions are frequently observed in Alzheimer brains. Not all of them are due to cerebral amyloid angiopathy. Some of them are related to the severity of the degenerative process itself, implying additional vascular factors
Autor:
Beatrice Arosio, Mauro Maccarrone, Daniela Mari, Patrizia Romualdi, Claudio D'Addario, A. Bulbarelli, Bernardo Dell'Osso, Daniela Galimberti, Cristina Gussago, S. Bastias Candia, Elio Scarpini, L. Mastronardi, Carlo Altamura, Sanzio Candeletti, Luigi Bergamaschini, E. Lonati
Publikováno v:
Neurodegenerative Diseases. 10:207-211
Background: Neurofibrillary tangles and senile plaques are hallmarks of Alzheimer’s disease (AD) although the molecular basis of their coexistence remains elusive. The peptidyl-prolyl cis/trans isomerase Pin1 acts on both tau and amyloid precursor
Publikováno v:
Neurodegenerative Diseases. 10:179-182
Background: Olfactory deficits and executive dysfunction have been reported in Parkinson’s disease (PD). However, the association between these deficits has not been thoroughly examined. Methods: We studied 44 PD subjects and 17 age-matched control
Autor:
John P. John, Meera Purushottam, Srikala Bharath, Lakshminarayan Kota, Sanjeev Jain, Mathew Varghese, Harsha N. Halahalli, Palanimuthu T. Sivakumar, Odity Mukherjee, Bhavani Shankara Bagepally
Publikováno v:
Neurodegenerative Diseases. 10:145-148
Introduction: Apolipoprotein E4 (ApoE ε4) polymorphism is a known genetic risk factor for Alzheimer’s disease (AD). Objectives: To evaluate the role of ApoE ε4 on white matter structural integrity in AD. Methods: Subjects were 32 patients with pr
Autor:
Svetlana Pejoska, Michael Pontecorvo, Graeme O'Keefe, Daniel Skovronsky, Rachel S. Mulligan, Gareth Jones, Nobuyuki Okamura, Gaël Chételat, Victor L. Villemagne, Hank F. Kung, Colin L. Masters, Christopher C. Rowe, John Drago
Publikováno v:
Neurodegenerative Diseases. 10:161-165
Background: The noninvasive evaluation of nigrostriatal dopaminergic integrity by PET can provide useful information for the differential diagnosis between dementia with Lewy bodies (DLB) and Alzheimer’s disease (AD). Objectives: To evaluate the di