Zobrazeno 1 - 10
of 86
pro vyhledávání: ''
Autor:
Jiao Lv, Qi Wan, Zhong-Yi Qian, Yong-Jie Huang, Lei Zhou, Zhi-Hao Mu, Pin Ye, Ying-Ying Zou, Wang Xie, Xiao-Peng Wang, Fang Wang, Xin-Jie Liu, Zhi-Hong Yang
Publikováno v:
Neurochemical research. 44(4)
Cognitive impairment in diabetes (CID) is a severe chronic complication of diabetes mellitus (DM). It has been hypothesized that diabetes can lead to cognitive dysfunction due to expression changes of excitatory neurotransmission mediated by N-methyl
Publikováno v:
Neurochemical research. 43(5)
Evidence indicates that experiencing early-life stress (ELS) is a risk factor for the development of mental disorders such as depression. Maternal separation stress (MS) is a valid animal model of ELS that caused to induce long-lasting effects on the
Publikováno v:
Neurochem Res
Anion channels and connexin hemichannels are permeable to amino acid neurotransmitters. It is hypothesized that these conductive pathways release GABA, thereby influencing ambient GABA levels and tonic GABAergic inhibition. To investigate this, we me
5-HT6 Receptor Agonist and Antagonist Against β-Amyloid-Peptide-Induced Neurotoxicity in PC-12 Cells
Publikováno v:
Neurochemical research. 42(5)
Beta-amyloid peptide (Aβ) induced neurotoxicity is considered as a hallmark of the pathogenesis of Alzheimer’s disease (AD). The present study demonstrated the neuroprotective role of 5-HT6 receptors against Aβ-induced neurotoxicity in PC-12 cell
Autor:
Kaichuang Si, Pengfei Fu, Wei Dan, Kunlun Wu, Yan Zhan, Quanhong Shi, Yuetao Wen, Yanfeng Xie
Publikováno v:
Neurochemical research. 42(8)
FK506, a calcineurin inhibitor, shows neuroprotective effects and has been associated with neurodegenerative diseases. Calcineurin A (CaNA), a catalytic subunit of calcineurin, mediates the dephosphorylation of various proteins. N-methyl-D-aspartate
Autor:
Di Wang, Yongfeng Zhang, Chunyue Wang, Dongxu Jia, Guangsheng Cai, Jiahui Lu, Zhang-Jin Zhang
Publikováno v:
Neurochemical research. 41(9)
The purpose of this study was to examine the effects of 18β-glycyrrhetinic acid (GA), a novel naturally derived agent, in suppressing prolactin (PRL) hyperactivity and reducing antipsychotic-induced hyperprolactinemia (hyperPRL) and the underlying m
Autor:
Fariba Khodagholi, Zahra Mansouri, Mohsen Majidi, Solaleh Khoramian Tusi, Zahra Mousavi, Nima Naderi
Publikováno v:
Neurochemical Research. 37:778-785
Most of the modulating effects of cannabinoids on pain are through putative cannabinoid CB1 and CB2 receptors. However, the involvement of other receptors is also suggested. Cannabinoid compounds with analgesic activity such as palmitoylethanolamide
Autor:
Yael Klin, Vivian I. Teichberg, Benjamin F. Gruenbaum, Sharon Ohayon, Eyal Sheiner, Shaun E. Gruenbaum, Yoram Shapira, Mathew Boyko, Barak Aricha-Tamir, Alexander Zlotnik
Publikováno v:
Neurochemical Research. 36:732-738
This study examines the effects of the activation of β1 and β2-adrenergic receptors on glutamate homeostasis in the blood of naive rats. Forty five male Sprague–Dawley rats were randomly assigned into one of seven treatment groups that were treat
Autor:
Shanaz Tejani-Butt, Irene Morganstern
Publikováno v:
Neurochemical Research. 35:1708-1715
The Wistar-Kyoto (WKY) rat strain has been described as an animal model of depressive behavior that consumes significantly greater amounts of alcohol compared to the Wistar (WIS) rat strain. Since the mesolimbic dopamine (DA) type-2 (D2) receptors me
Autor:
Maria Dorota Majewska, Teresa Bobrowicz, Paweł Mierzejewski, Mieszko Olczak, Michalina Duszczyk
Publikováno v:
Neurochemical Research
Thimerosal added to some pediatric vaccines is suspected in pathogenesis of several neurodevelopmental disorders. Our previous study showed that thimerosal administered to suckling rats causes persistent, endogenous opioid-mediated hypoalgesia. Here