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pro vyhledávání: '"Richard Salvi"'
Autor:
Chiemi Tanaka, Guang-Di Chen, Donald Henderson, Richard Salvi, Senthilvelan Manohar, Donald E. Coling, Bo Hua Hu
Publikováno v:
Neurobiology of aging. 33(8)
The biological mechanisms that give rise to age-related hearing loss (ARHL) are still poorly understood. However, there is growing recognition that oxidative stress may be an important factor. To address this issue, we measured the changes in the exp
Publikováno v:
Neurobiology of aging. 30(10)
The ahl locus, shown to be a strain-specific Cdh23 dimorphism, contributes to age-related hearing loss in many inbred mouse strains. A/J mice begin to lose hearing by 4 weeks of age, much earlier than C57BL/6J (B6) mice, although both strains have th
Publikováno v:
Neurobiology of aging. 20(1)
Age-related hearing loss in humans and many strains of mice is associated with a base-to-apex gradient of cochlear hair cell loss. To determine if copper/zinc superoxide dismutase (Cu/Zn SOD) deficiency influences age-related cochlear pathology, we c