Zobrazeno 1 - 10
of 4 295
pro vyhledávání: ''
Autor:
Hiroaki Goto, Laura Dima, Steven G. DuBois, Ricarda Norenberg, Jordan R. Hansford, Esther De La Cuesta, Juneko E. Grilley-Olson, Ingrid Øra, David S. Hong, Theodore W. Laetsch, Karsten Nysom, Joanna Stefanowicz, Martin Højgaard, Valentina Boni, Hyoung Jin Kang, Julia C. Chisholm, Makoto Tahara, Birgit Geoerger, François Doz, Soledad Gallego-Melcon, David S. Ziegler, Alexander Drilon, Cornelis M. van Tilburg, Hyun Cheol Chung, Anne Thorwarth, Igor T. Gavrilovic, Antoine Italiano, Michael Capra, Sébastien Perreault, Nicolas U. Gerber
Publikováno v:
Neuro-Oncology. 24:997-1007
Background Larotrectinib is a first-in-class, highly selective tropomyosin receptor kinase (TRK) inhibitor approved to treat adult and pediatric patients with TRK fusion-positive cancer. The aim of this study was to evaluate the efficacy and safety o
Autor:
Gerald A. Grant, Michael Zhang, Alireza Radmanesh, Thomas S. Jacques, Ozgur Oztekin, Samuel H. Cheshier, Stefan M. Pfister, Chang Y Ho, Robert Lober, Kristen W. Yeom, Edward Wang, Lydia T. Tam, Kshitij Mankad, Michael D. Taylor, Eric Chen, Jason N. Wright, Sarah A. Mattonen, Birgit Ertl-Wagner, Vijay Ramaswamy, Jordan Nemelka, Kristian Aquilina, Nicholas A Vitanza, Paul G. Fisher, Mourad Said, Emre Altinmakas, Alok Jaju, Derek Yecies, Sebastian Toescu, Michelle Han, Matthias W Wagner
Publikováno v:
Neuro-Oncology. 24:986-994
Background The risk profile for posterior fossa ependymoma (EP) depends on surgical and molecular status [Group A (PFA) versus Group B (PFB)]. While subtotal tumor resection is known to confer worse prognosis, MRI-based EP risk-profiling is unexplore
Autor:
Jane E. Minturn, Ayman El-Sheikh, Gustavo Sevlever, Michelle Monje-Deisseroth, Hetal Dholaria, Karen Tsui, Maryam Fouladi, Pratiti Bandopadhayay, Cynthia Hawkins, Scott L Coven, Lindsay Kilburn, Christopher L. Tinkle, David S. Ziegler, Eric Sandler, Yvan Samson, Jordan R. Hansford, Eric Bouffet, Sylvia Cheng, Sridharan Gururangan, Kathleen Dorris, Tim Hassall, Mohamed S. Zaghloul, Carl Koschmann, Sarah Leary, Mercedes Garcia Lombardi, Blaise V. Jones, Paul G. Fisher, Anthony Asher, Rachid Drissi, Blanca Diez, Kenneth J. Cohen, Jie Ma, Adriana Fonseca, Katie Black, Nicholas G. Gottardo, Stewart Goldman, Christine E. Fuller, Tabitha Cooney, Moatasem El-Ayadi, Adam Lane, Brooklyn Chaney, Mariko DeWire, Robert J. Greiner, Ute Bartels, Margot A Lazow, James L. Leach, Lars M. Wagner, Roger J. Packer
Publikováno v:
Neuro Oncol
Background Diffuse intrinsic pontine glioma (DIPG) remains a clinico-radiologic diagnosis without routine tissue acquisition. Reliable imaging distinction between DIPG and other pontine tumors with potentially more favorable prognoses and treatment c
Autor:
Sung Tae Kim, Minjung Seong, Tracy T. Batchelor, Ji Eun Park, Choong Gon Choi, Sung Soo Ahn, Lakshmi Nayak, Seung Koo Lee, Chong Hyun Suh, Kichang Han, Sang Min Lee, Seung Chai Jung, Jeffrey P. Guenette, Raymond Y. Huang, Seung Hong Choi, Ho Sung Kim, Sang Joon Kim, Jeong Hoon Kim
Publikováno v:
Neuro-Oncology. 24:482-491
Background We aimed to investigate the detection rate of body CT or PET/CT for sites of extracranial disease in patients with a new pathological diagnosis of CNS DLBCL and to identify factors associated with sites of extracranial disease. Methods An
Autor:
Martha Quezado, Hye-Jung Chung, Lola Saidkhodjaeva, Manoj Tyagi, Zhichao Wu, Sushma Nagaraj, Mark R. Gilbert, Andreas von Deimling, Rust Turakulov, Shannon Skarshaug, Michael Newford, Antonios Papanicolau-Sengos, Drew Pratt, Kenneth Aldape, Kayla O’Donnell, Abigail K. Suwala, Candice Perry, Svetlana Pack, Vineela Gangalapudi, Shirin Karimi, Farshad Nassiri, Yasin Mamatjan, Zied Abdullaev, Felix Sahm, Valerie Zgonc, Liqiang Xi, Gelareh Zadeh, Mark Raffeld, Kristin Valdez, Eytan Ruppin
Publikováno v:
Neuro Oncol
Background Accurate CNS tumor diagnosis can be challenging, and methylation profiling can serve as an adjunct to classify diagnostically difficult cases. Methods An integrated diagnostic approach was employed for a consecutive series of 1258 surgical
Autor:
Sherwin Tavakol, Elizabeth B. Claus, Rameen Beroukhim, Brian M. Alexander, Harish N. Vasudevan, David R. Raleigh, Sandro Santagata, Adrian M. Dubuc, Azra H. Ligon, Eduardo A Maury, Ossama Al-Mefty, Noah F. Greenwald, Samantha E Hoffman, Eleanor Woodward, Joseph Driver, Ian F. Dunn, Patrick Y. Wen, Ayal A. Aizer, Keith L. Ligon, Abrar Choudhury, Wenya Linda Bi, Farshad Nassiri, Varun Bhave, Kenneth Aldape, Stephen T. Magill, David A. Reardon, Malak Abedalthagafi, Gelareh Zadeh
Publikováno v:
Neuro-oncology, vol 24, iss 5
Background Meningiomas are the most common primary intracranial tumor in adults. Clinical care is currently guided by the World Health Organization (WHO) grade assigned to meningiomas, a 3-tiered grading system based on histopathology features, as we
Autor:
John Kelly, David Ben-Israel, Miran Skrap, Hugues Duffau, Jacob S. Young, Barbara Tomasino, Mitchel S. Berger, Tamara Ius, Maurizio Polano, Sam Ng
Publikováno v:
Neuro-Oncology
Neuro-Oncology, Oxford University Press (OUP), 2021, ⟨10.1093/neuonc/noab210⟩
Neuro Oncol
Neuro-Oncology, Oxford University Press (OUP), 2021, ⟨10.1093/neuonc/noab210⟩
Neuro Oncol
Background The role of surgery for incidentally discovered diffuse incidental low-grade gliomas (iLGGs) is debatable and poorly documented in current literature. Objective The aim was to identify factors that influence survival for patients that unde
Autor:
Michael E. Berens, Quinn T. Ostrom, Gi-Ming Wang, Jill S. Barnholtz-Sloan, Nirav Patil, Robert Lanese, Joshua B. Rubin, Justin D. Lathia, James R. Connor, Gino Cioffi, Carol Kruchko, Kristin Waite
Publikováno v:
Neuro-Oncology. 24:302-310
Background Gliomas are the most common type of malignant brain and other CNS tumors, accounting for 80.8% of malignant primary brain and CNS tumors. They cause significant morbidity and mortality. This study investigates the intersection between age
Publikováno v:
Neuro Oncol
Background Venous thromboembolism (VTE) occurs in up to 30% of patients with high-grade glioma (HGG). Concern for increased risk of intracranial hemorrhage (ICH) with therapeutic anticoagulation (AC) complicates VTE treatment. Some retrospective stud
Autor:
Gaspar J. Kitange, Katrina K. Bakken, Jann N. Sarkaria, Matthew L. Kosel, Brett L. Carlson, Caterina Giannini, Mark A. Schroeder, Paul A. Decker, Anne Schmitt-Hoffmann, Gautham Gampa, Felix Bachmann, Rachael A. Vaubel, Jenny L. Pokorny, Lihong He, Ann C. Mladek, Zeng Hu, Surabhi Talele, Paul M.J. McSheehy, William F. Elmquist, Danielle M. Burgenske, Heidi Lane, Jeanette E. Eckel-Passow
Publikováno v:
Neuro Oncol
Background Glioblastoma (GBM) is an incurable disease with few approved therapeutic interventions. Radiation therapy (RT) and temozolomide (TMZ) remain the standards of care. The efficacy and optimal deployment schedule of the orally bioavailable sma