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Publikováno v:
Neuro Oncol
The management of aggressive meningiomas remains challenging due to limited treatment options besides surgical removal and radiotherapy. High recurrence rates and lack of effective chemotherapies may be reasons for the unfavorable prognosis of these
Autor:
Franz Ricklefs, Manfred Westphal, Ines Stevic, Christian Mende, Sven O. Eicker, Jennifer Jones, Katrin Lamszus, Joshua A. Welsh
Publikováno v:
Neuro Oncol
BACKGROUND: Extracellular vesicles (EVs) play an important role in cell-cell communication in different types of tumors, carrying multiple layers of biological functional molecules, including proteins, RNA, DNA and lipids. We previously demonstrated
Publikováno v:
Neuro-Oncology. 20:vi73-vi73
KIF11 is a highly conserved motor protein, which plays an important role in cell division by separating the spindle poles. KIF11 have been reported to be involved in multiple cancer types including melanoma, retinoblastoma, and glioma. In our previou
Autor:
Anita Lal, Raimund Firsching, Werner Paulus, Christian Ewald, Christian Huebner, Rolf Kalff, Christian Mawrin, Matthias Evert, Daniela Haase, Gerburg Keilhoff, David H. Gutmann, Stefan Schmidl
Publikováno v:
Neuro-Oncology. 12:844-854
High levels of fatty acid synthase (FAS) expression have been reported in hormone receptor-positive tumors, including prostate, breast, and ovarian cancers, and its inhibition reduces tumor growth in vitro and in vivo. Similar to other hormone recept
Autor:
Ayushi Sahay, Prakash Shetty, Aliasgar Moiyadi, Rakesh Jalali, Tejpal Gupta, Sridhar Epari, Jayantsastri Goda, Vinayak Kadam
Publikováno v:
Neuro-Oncology. 19:vi133-vi133
Autor:
Otto Muzik, Edit Bosnyák, Kaushik Varadarajan, William J. Kupsky, Anthony R. Guastella, Csaba Juhász, Natasha L. Robinette, David O. Kamson, Sharon K. Michelhaugh, Sandeep Mittal
Publikováno v:
Neuro-Oncology.
Background. Increased tryptophan metabolism via the kynurenine pathway (KP) is a key mechanism of tumoral immune suppression in gliomas. However, details of tryptophan metabolism in meningiomas have not been elucidated. In this study, we evaluated in
Autor:
Marcel Chatel, Jean Christophe Gollmer, Alain Dubreuil, Annie Ladoux, Philippe Paquis, Christian Frelin, Jeanine Gioanni
Publikováno v:
Neuro-Oncology. 2:80-86
Growth of human malignant gliomas is stringently dependent on an angiogenic process that probably involves vascular endothelial growth factor (VEGF). Expressions of mRNA coding for the different forms of VEGF were analyzed in surgical specimens from
Publikováno v:
Neuro-Oncology. 17:viii4.5-viii5
INTRODUCTION: The body absorbs a wide variety of elements from the environment whose concentration in the blood is regulated by homeostatic mechanisms catalysed and regulated by enzymes and enzyme inhibitors. Trace elements act as cofactors in enzyme
Autor:
Scott Lindhorst, Naren L. Banik, Jerry J. Jaboin, Jeffery J. Raizer, Arabinda Das, Sunil J. Patel, William A. Vadergrift, Michele L Decandio, Vikram N. Samant, Pierre Giglio, Abhay K. Varma
Publikováno v:
Neuro-Oncology. 17:v130.2-v130
Meningiomas are the second most common brain tumor, with a small proportion of these tumors being atypical or malignant. The aggressive subtypes are characterized by a capacity for invasion of normal brain with frequent recurrence patterns. Effective
P01 * AN UNUSUAL CASE OF A METASTATIC ADENOCARCINOMA OF THE PROSTATE INTO AN INTRACRANIAL MENINGIOMA
Publikováno v:
Neuro-Oncology. 16:vi1-vi1
INTRODUCTION: Tumour to tumour metastatis is an unusual but well recognized phenomenon. We present a rare case of a metastatic prostatic adenocarcinoma into a meningioma. METHOD: A 58 year old right handed gentleman was referred to our neuro-oncology