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Publikováno v:
Nephron. 146:190-196
Background: Hyperkalaemia with metabolic acidosis is common but under-reported following kidney transplantation. Calcineurin inhibitors, such as tacrolimus, are widely used in the management of transplant patients and are associated with the developm
Publikováno v:
Nephron
Elevated fibroblast growth factor 23 (FGF23) levels are markers and potential mediators, of adverse outcomes in acute kidney injury (AKI). We recently identified glycerol-3-phosphate (G-3-P), a glycolysis byproduct, as a kidney-derived factor that ci
Autor:
Roman Fiedler, Matthias Girndt, Frank Bernhard Kraus, Eric Seibert, Christof Ulrich, Bogusz Trojanowicz, Gabriele I. Stangl
Publikováno v:
Nephron Clin Pract
Introduction: Low serum testosterone is related to increased mortality in male dialysis patients. An association of vitamin D status with serum androgen levels with concordant seasonal variation has been described, but it is undecided whether vitamin
Publikováno v:
Nephron. 145:748-759
Background: We intended to investigate the function of circular RNA RasGEF domain family member 1B (circ_RASGEF1B) in lipopolysaccharide (LPS)-induced septic acute kidney injury (AKI) cell model and its associated mechanism. Methods: TCMK-1 cells wer
Publikováno v:
Nephron. 145:123-132
Introduction: In hospitalized patients, information on preadmission kidney function is often missing, impeding timely and accurate acute kidney injury (AKI) detection and affecting results of AKI-related studies. Objective: In this study, we provided
Autor:
Mehmet Bülbül, Evrim Kargın Çakıcı, Nilüfer Arda, Tülin Güngör, Eda Didem Kurt Şükür, Semanur Özdel, Fatma Yazılıtaş
Publikováno v:
Nephron. 144:222-227
Objectives: Familial Mediterranean fever (FMF) is a monogenic auto-inflammatory disease which might rarely cause glomerulopathy in patients. The aim of this study was to determine the clinical, demographic, and genetic characteristics and type of glo
Publikováno v:
Nephron. 144:255-260
Aims: This study aimed to investigate the association of single nucleotide polymorphisms (SNPs) within vascular endothelial growth factor (VEGF) gene and additional gene-environment interaction with renal cell carcinoma (RCC) risk. Methods: PCR-restr
Autor:
Farida Hanim Islahudin, Mohd Makmor-Bakry, Hanita Othman, Nor Asyikin Mohd Tahir, Shamin Mohd Saffian, Hamizah Abdul Manan, Abdul Halim Abdul Gafor
Publikováno v:
Nephron. 144:204-212
Background/Aims: G73A polymorphism in the CST3 gene of cystatin C has been associated with Alzheimer’s disease, age-related macular degeneration, and cardiovascular disease. However, studies investigating the influence of this genetic variability o
Autor:
Qingzhen Gao, Shan Zhang, Huili Jiang, Ruibin Zhang, Xiaoping Wang, Fang Liu, Xia Xue, Min Lu
Publikováno v:
Nephron. 144:84-95
Background: The protective effects of taurine supplementation on diabetic kidney disease (DKD) have been defined, but the mechanisms are not quite clear yet. TRPC6 has been shown to function in the homeostasis of podocytes, but whether TRPC6-modulate
Publikováno v:
Nephron. 144:506-508
Kidney diseases during chemotherapy treatment are variable, with different manifestations depending on the drugs used. Trifluridine/tipiracil is a treatment used in refractory metastatic digestive cancers. Its renal toxicity is poorly described. We r