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Autor:
Dan-Avi Landau, Catherine J. Wu, Chip Stewart, Mara Rosenberg, Alyssa Macbeth, Mendy Miller, Amaro Taylor-Weiner, Gad Getz, Thomas J. Giordano, Niall J. Lennon, Esther Rheinbay
Publikováno v:
Nature methods
Comparison of sequencing data from a tumor sample with data from a matched germline control is a key step for accurate detection of somatic mutations. Detection sensitivity for somatic variants is greatly reduced when the matched normal sample is con