Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jennifer A. Wargo"'
Autor:
Tina Cascone, Cheuk H. Leung, Annikka Weissferdt, Apar Pataer, Brett W. Carter, Myrna C. B. Godoy, Hope Feldman, William N. William, Yuanxin Xi, Sreyashi Basu, Jing Jing Sun, Shalini S. Yadav, Frank R. Rojas Alvarez, Younghee Lee, Aditya K. Mishra, Lili Chen, Monika Pradhan, Haiping Guo, Ansam Sinjab, Nicolas Zhou, Marcelo V. Negrao, Xiuning Le, Carl M. Gay, Anne S. Tsao, Lauren Averett Byers, Mehmet Altan, Bonnie S. Glisson, Frank V. Fossella, Yasir Y. Elamin, George Blumenschein, Jianjun Zhang, Ferdinandos Skoulidis, Jia Wu, Reza J. Mehran, David C. Rice, Garrett L. Walsh, Wayne L. Hofstetter, Ravi Rajaram, Mara B. Antonoff, Junya Fujimoto, Luisa M. Solis, Edwin R. Parra, Cara Haymaker, Ignacio I. Wistuba, Stephen G. Swisher, Ara A. Vaporciyan, Heather Y. Lin, Jing Wang, Don L. Gibbons, J. Jack Lee, Nadim J. Ajami, Jennifer A. Wargo, James P. Allison, Padmanee Sharma, Humam Kadara, John V. Heymach, Boris Sepesi
Publikováno v:
Nature Medicine. 29:593-604
Neoadjuvant ipilimumab + nivolumab (Ipi+Nivo) and nivolumab + chemotherapy (Nivo+CT) induce greater pathologic response rates than CT alone in patients with operable non-small cell lung cancer (NSCLC). The impact of adding ipilimumab to neoadjuvant N
Autor:
Elizabeth M. Park, Manoj Chelvanambi, Neal Bhutiani, Guido Kroemer, Laurence Zitvogel, Jennifer A. Wargo
Publikováno v:
Nature Medicine. 28:690-703
Microorganisms within the gut and other niches may contribute to carcinogenesis, as well as shaping cancer immunosurveillance and response to immunotherapy. Our understanding of the complex relationship between different host-intrinsic microorganisms
Autor:
Cheuk Hong Leung, Wayne L. Hofstetter, John V. Heymach, Alexandre Reuben, Myrna C.B. Godoy, Ara A. Vaporciyan, Padmanee Sharma, Yasir Elamin, Neda Kalhor, Robert R. Jenq, Junya Fujimoto, Tina Cascone, Anne S. Tsao, William N. William, Charles Lu, Frank E. Mott, Nadim J. Ajami, Don L. Gibbons, Jack A. Roth, David C. Rice, Luisa M. Solis, Hai T. Tran, Brett W. Carter, Lauren Averett Byers, Andrew Futreal, Lorenzo Federico, Annikka Weissferdt, Garrett L. Walsh, Reza J. Mehran, Chantale Bernatchez, George R. Blumenschein, Jennifer A. Wargo, Heather Lin, Cara Haymaker, Xiuning Le, Jonathan M. Kurie, Mehmet Altan, James P. Allison, Stephen G. Swisher, Edwin R. Parra, Boris Sepesi, Hitoshi Dejima, Frank V. Fossella, Jianjun Zhang, Bonnie S. Glisson, Mara B. Antonoff, Abdul Wadud Khan, Apar Pataer, Alejandro Francisco-Cruz, Ignacio I. Wistuba, Humam Kadara, J. Jack Lee, Ferdinandos Skoulidis
Publikováno v:
Nat Med
Ipilimumab improves clinical outcomes when combined with nivolumab in metastatic non-small cell lung cancer (NSCLC), but its efficacy and impact on the immune microenvironment in operable NSCLC remain unclear. We report the results of the phase 2 ran
Autor:
Christian U. Blank, Rodabe N. Amaria, Jennifer A. Wargo, Bart A. van de Wiel, Georgina V. Long, Hussein Abdul-Hassan Tawbi, Alexander C. Huang, Xiaowei Xu, Richard A. Scolyer, Tara C. Mitchell, Giorgos C. Karakousis, Alexander C.J. van Akkooi, Michael A. Davies, Andrew J. Spillane, Elisa A. Rozeman, Alexander M. Menzies, Robyn P. M. Saw, Michael T. Tetzlaff, Ahmad A. Tarhini, Thomas E. Pennington, Elizabeth M. Burton, Paolo A. Ascierto, Serigne Lo
Publikováno v:
Nature Medicine. 27:301-309
The association among pathological response, recurrence-free survival (RFS) and overall survival (OS) with neoadjuvant therapy in melanoma remains unclear. In this study, we pooled data from six clinical trials of anti-PD-1-based immunotherapy or BRA
Autor:
Gottumukkala S. Raju, Edwin Roger Parra, Jorge Blando, Matthew T. Campbell, Sumit K. Subudhi, Yinghong Wang, Hamzah Abu-Sbeih, Kati Choi, Jianjun Gao, Zhi-Dong Jiang, Beth A. Helmink, John R. Stroehlein, Chia-Chi Chang, James P. Allison, Diana H. Wiesnoski, Jennifer A. Wargo, Dipen M. Maru, Hebert L. DuPont, Robert R. Jenq, Christopher A. Sanchez, Michael T. Tetzlaff, Padmanee Sharma, Alejandro Francisco-Cruz, Vancheswaran Gopalakrishnan, Alexander J. Lazar
Publikováno v:
Nature Medicine. 24:1804-1808
We report the first case series of immune checkpoint inhibitors (ICI)-associated colitis successfully treated with fecal microbiota transplantation, with reconstitution of the gut microbiome and a relative increase in the proportion of regulatory T-c
Autor:
Neil D. Gross, Randal S. Weber, Wen-Jen Hwu, Jeffrey E. Lee, Shaojun Zhang, Courtney W. Hudgens, Vancheswaran Gopalakrishnan, Padmanee Sharma, Alexander J. Lazar, Rodabe N. Amaria, Merrick I. Ross, Amy C. Hessel, Christine N. Spencer, Lauren Simpson, Richard A. Ehlers, Jeffrey E. Gershenwald, Michael A. Davies, Michael K. Wong, Hussein Abdul-Hassan Tawbi, James P. Allison, Liberty Posada, Daniel K. Wells, Robin Kageyama, Sapna Pradyuman Patel, Isabella C. Glitza, Adi Diab, Denái R. Milton, Michael T. Tetzlaff, Richard E. Royal, Scott E. Woodman, Carol M. Lewis, Miles C. Andrews, Alexandre Reuben, Sangeetha M. Reddy, Lauren E. Haydu, Victor G. Prieto, Ehab Y. Hanna, Patrick Hwu, Elizabeth M. Burton, Janice N. Cormier, Jennifer A. Wargo, Anthony Lucci, Stephen Y. Lai, Jorge Blando, Linghua Wang
Publikováno v:
Nature medicine
Preclinical studies suggest that treatment with neoadjuvant immune checkpoint blockade is associated with enhanced survival and antigen-specific T cell responses over adjuvant treatment1; however, optimal regimens have not been defined. Herein, we re
Autor:
Christopher J. Logothetis, Curtis A. Pettaway, Jianjun Gao, Jianfeng Chen, Lewis Zhichang Shi, Eleni Efstathiou, Patricia Troncoso, Jennifer A. Wargo, Hong Chen, Jingjing Sun, John F. Ward, Manuel A. Sepulveda, Ignacio I. Wistuba, Luis M Vence, Hao Zhao, Padmanee Sharma, Jorge Blando, James P. Allison, Sumit K. Subudhi
Publikováno v:
Nature Medicine. 23:551-555
To date, anti-CTLA-4 (ipilimumab) or anti-PD-1 (nivolumab) monotherapy has not been demonstrated to be of substantial clinical benefit in patients with prostate cancer. To identify additional immune-inhibitory pathways in the prostate-tumor microenvi
Autor:
Edwin R. Parra, Hebert L. DuPont, Alexander J. Lazar, Kati Choi, Vancheswaran Gopalakrishnan, Diana H. Wiesnoski, Hamzah Abu-Sbeih, Padmanee Sharma, Chia-Chi Chang, Alejandro Francisco-Cruz, Zhi-Dong Jiang, James P. Allison, Yinghong Wang, Sumit K. Subudhi, Robert R. Jenq, Jennifer A. Wargo, John R. Stroehlein, Christopher A. Sanchez, Matthew T. Campbell, Gottumukkala S. Raju, Jorge Blando, Michael T. Tetzlaff, Beth A. Helmink, Dipen M. Maru, Jianjun Gao
Publikováno v:
Nature Medicine. 25:188-188
In the version of this article originally published, an author was missing from the author list. Alexander J. Lazar should have been included between Jorge M. Blando and James P. Allison. The author has been added to the list, and the author contribu
Autor:
Denái R. Milton, Michael T. Tetzlaff, Carol M. Lewis, Daniel K. Wells, Alexander J. Lazar, Anthony Lucci, Miles C. Andrews, Randal S. Weber, Lauren E. Haydu, Richard E. Royal, Liberty Posada, Christine N. Spencer, Stephen Y. Lai, Victor G. Prieto, Alexandre Reuben, Michael A. Davies, M. Wong, Rodabe N. Amaria, Ehab Y. Hanna, Patrick Hwu, Jeffrey E. Lee, Elizabeth M. Burton, Sapna Pradyuman Patel, Adi Diab, Vancheswaran Gopalakrishnan, Jorge Blando, Wen-Jen Hwu, Janice N. Cormier, Robin Kageyama, Padmanee Sharma, Jennifer A. Wargo, Jeffrey E. Gershenwald, Richard A. Ehlers, Merrick I. Ross, Amy C. Hessel, James P. Allison, Courtney W. Hudgens, Lauren Simpson, Scott E. Woodman, Linghua Wang, Neil D. Gross, Shaojun Zhang, Isabella C. Glitza, Sangeetha M. Reddy, Hussein Abdul-Hassan Tawbi
Publikováno v:
Nature Medicine. 24:1941-1941
In the version of this article originally published, there was an error in Fig. 1. In the neoadjuvant phase column, the n values for arms A and B were both reported to be 20. The n values for arms A and B were actually 12 and 11, respectively. Also,
Autor:
Rodabe N. Amaria, Sangeetha M. Reddy, Hussein A. Tawbi, Michael A. Davies, Merrick I. Ross, Isabella C. Glitza, Janice N. Cormier, Carol Lewis, Wen-Jen Hwu, Ehab Hanna, Adi Diab, Michael K. Wong, Richard Royal, Neil Gross, Randal Weber, Stephen Y. Lai, Richard Ehlers, Jorge Blando, Denái R. Milton, Scott Woodman, Robin Kageyama, Daniel K. Wells, Patrick Hwu, Sapna P. Patel, Anthony Lucci, Amy Hessel, Jeffrey E. Lee, Jeffrey Gershenwald, Lauren Simpson, Elizabeth M. Burton, Liberty Posada, Lauren Haydu, Linghua Wang, Shaojun Zhang, Alexander J. Lazar, Courtney W. Hudgens, Vancheswaran Gopalakrishnan, Alexandre Reuben, Miles C. Andrews, Christine N. Spencer, Victor Prieto, Padmanee Sharma, James Allison, Michael T. Tetzlaff, Jennifer A. Wargo
Publikováno v:
Nature Medicine. 24:1942-1942